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Other Targets

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Cat. No. Product Name Field of Application Chemical Structure
DC12055 DC1-SMe DC1-Sme is an antibody conjugate of phosphate prodrug of cytotoxic DNA alkylators for the targeted treatment of cancer.
DC12554 DC661 Featured DC661 (DC-661) is a novel dimeric chloroquine (CQ) that is capable of deacidifying the lysosome and inhibiting autophagy significantly better than HCQ, targets palmitoyl-protein thioesterase 1 (PPT1).
DC20175 Ripretinib (DCC-2618) Featured DCC-2618 is an orally bioavailable switch pocket control inhibitor of wild-type and mutated forms of the tumor-associated antigens (TAA) mast/stem cell factor receptor (SCFR) KIT and PDGFR-alpha, with IC50 values of 4 nM, 8 nM, 18 nM, 5 nM and 14 nM.
DC24137 DCVC DCVC (S-(1,2-dichlorovinyl)-L-cysteine) is an active metabolite of trichloroethylene.
DCAPI1304 D-Cycloserine D-Cycloserine
DC12593 DD-03-171 DD-03-171 is a small molecule, CGI1746-based BTK degrader (PROTAC, biochemical IC50=5.1 nM) that efficiently degrade C481S-BTK, exhibits enhanced anti-proliferative effects on mantle cell lymphoma (MCL) cells in vitro by degrading BTK, IKFZ1 and IKFZ3.
DC20947 DDD 85646 Featured DDD 85646 is a potent, specific, dual N-Myristoyltransferase NMT1/NMT2 inhibitor with IC50 of 17 nM/22 nM respectively.
DC12521 DDR1 inhibitor 2.45 DDR1 inhibitor 2.45 (Compound 2.45) is a novel potent, selective, bioavailable Discoidin Domain Receptor 1 (DDR1) inhibitor with IC50 of 29 nM, displays 64-fold selectivity over DDR2 in biochemical assays.
DC23844 DDR1 inhibitor 7rh DDR1 inhibitor 7rh is a potent, selective, ATP-competitive, orally available Discoidin domain receptor 1 (DDR1) inhibitor with IC50 of 6.8 nM in cell-free kinase assays.
DC7398 DDR1-IN-1 Featured DDR1-IN-1 is a potent and selective DDR1 receptor tyrosine kinase inhibitor with IC50/EC50 of 105 nM/87 nM; 4-fold less potent for DDR2 (IC50= 413 nM).
DC23857 DDR2-IN-5 DDR2-IN-5 is a potent, dual DDR2/SRC inhibitor with IC50 of 56/12 nM, potently suppresses DDR2 mutated cell lines HCC-366 and NCI-H2286 with IC50 of 0.44 uM and 0.29 uM..
DC12560 DDR-TRK-1 DDR-TRK-1 (DDR1 inhibitor 6j) is a potent, selective selective DDR1 inhibitor with IC50 of 9.4 nM, also potently inhibits TRK family with IC50 of 18-100 nM.
DC4193 Decitabine Featured Decitabine is a potent inhibitor of DNA methylation with IC50 of 438 nM and 4.38 nM in HL-60 and KG1a cells, respectively.
DC12144 Decursin ((+)-Decursin) Featured Decursin is an anticancer agent, with potential anti-inflammatory activity.
DC10822 Defensamide(MHP) Featured Defensamide, also known as MHP and methyl caprooyl tyrosinate, is an activator of sphingosine kinase (SPHK1), and significantly stimulates CAMP mRNA and protein production in KC.
DCAPI1107 Deferasirox (Exjade) Featured Deferasirox (Exjade)
DC7399 Deferitrin Featured Deferitrin (GT-56-252) is the first drug in a class of desferrithiocin-derived hexadentate iron chelators.
DC11332 Degarelix (acetate) Featured Degarelix is a synthetic gonadotropin-releasing hormone receptor (GNRHR) antagonist (IC50 = 3 nM in HEK293 cells expressing the human receptor).
DC9337 Deguelin Featured Deguelin, a naturally occurring rotenoid, is known to be an Akt inhibitor and to have an anti-tumor effect on several cancers; decrease levels of phosphorylated Akt.
DC5201 Dehydroepiandrosterone (DHEA) Dehydroepiandrosterone(DHEA) is a 19-carbon endogenous natural steroid hormone.
DC23727 Dehydromutactin Dehydromutactin is a small molecule inhibitor of RNA-binding protein Hu protein R (HuR) that interferes the HuR homodimerization with Kd of 40 nM.
DC12073 Dehydronitrosonisoldipine Dehydronitrosonisoldipine is a calcium channel antagonist.
DC10458 Delafloxacin(ABT-492) Featured Delafloxacin (RX-3341, ABT-492) is a fluoroquinolone antibiotic agent.
DC20116 Delafloxacin meglumine (ABT492 meglumine; RX-3341 meglumine; WQ-3034 meglumine) Featured Delafloxacin meglumine (ABT492 meglumine; RX-3341 meglumine; WQ-3034 meglumine) is a broad-spectrum fluoroquinolone antibiotic. Delafloxacin has a broad spectrum of activity that includes drug-resistant Staphylococcus aureus, Streptococcus pneumoniae, and
DC20772 Deleobuvir Deleobuvir (BI-207127, BI207127) is a potent, selective HCV NS5B polymerase inhibitor with IC50 of 50 nM against GT-1 HCV polymerase activity.
DC20948 Deltasonamide 2 Deltasonamide 2 (Deltasonamide-2) is a novel small molecule inhibitor of PDE6δ/KRas interaction with Kd of 385 pM.
DC26004 delta-Valerobetaine (hydrobromide) Featured Delta-Valerobetaine (hydrobromide) is a precursor of trimethylamine N-oxide (TMAO).
DC20949 Deltazinone 1 Deltazinone 1 (Deltazinone1) is a novel highly selective PDEδ inhibitor that inhibits PDEδ/Ras interaction with Kd of 8±4 nM.
DC10850 Dencichine Dencichin is a non-protein amino acid originally extracted from Panax notoginseng, and can inhibit HIF-prolyl hydroxylase-2 (PHD-2) activity.
DC7199 Denibulin (MN-029) Denibulin (MN-029) is a novel vascular-disrupting agent that reversibly inhibits microtubule assembly, resulting in disruption of the cytoskeleton of tumor vascular endothelial cells.

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