| DC8712 |
Deoxycorticosterone acetate
Featured
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Deoxycorticosterone acetate is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as a precursor to aldosterone. |
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| DC10308 |
Deoxycytidine triphosphate |
Deoxycytidine triphosphate (dCTP), a nucleoside triphosphate, is a raw material in DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing. |
|
| DC21402 |
Deoxynyboquinone |
Deoxynyboquinone, also known as DNQ, is a potent inducer of cancer cell death. DNQ potently induces death of cancer cells in culture, with IC(50) values between 16 and 210 nM. In addition, unlike the experimental therapeutic elesclomol, DNQ is still able to induce cancer cell death under hypoxic conditions. This mechanistic understanding of DNQ will allow for a more comprehensive evaluation of the potential of direct ROS generation as an anticancer strategy, and DNQ itself has potential as a novel anticancer agent. |
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| DC23791 |
Deoxyspergualin |
Deoxyspergualin is a derivative of the antitumor antibiotic spergualin that binds specifically to Hsc70, also inhibits poly(rC) binding protein 2 (PCBP2).. |
|
| DC24197 |
Derenofylline(SLV320)
Featured
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Derenofylline(SLV320) is a potent and selective adenosine A1 receptor antagonist (Ki values are 1, 200, 398 and 3981 nM at human A1, A3, A2A and A2B receptors respectively). |
|
| DC11055 |
Desmethyl dabrafenib
Featured
|
Desmethyl dabrafenib (GSK2167542, Dabrafenib metabolite M8) is the desmethyl- metabolic byproduct of Dabrafenib, ameliorates developmental pathologies of Kabuki Syndrome in vivo.. |
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| DCAPI1287 |
Desonide |
Desonide |
|
| DC11331 |
Desoximetasone |
Desoximetasone is a glucocorticoid. |
|
| DC9631 |
Desvenlafaxine (succinate hydrate) |
Desvenlafaxine succinate hydrate is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI). |
|
| DC20273 |
Deuterated AZ5104
Featured
|
Deuterated AZ5104 is a potent EGFR inhibitor. |
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| DCAPI1025 |
Dexamethasone
Featured
|
Dexamethasone is a potent synthetic member of the glucocorticoid class of steroid drugs used as an anti-inflammatory and immunosuppressant. |
|
| DC10231 |
D panthenol |
Dexpanthenol is an alcoholic analogue of D-pantothenic acid and cholinergic agent. |
|
| DCAPI1475 |
Dexrazoxane Hydrochloride |
Dexrazoxane Hydrochloride |
|
| DCAPI1431 |
Dextromethorphan hydrobromide |
Dextromethorphan hydrobromide |
|
| DC9093 |
Dextromethorphan HBr |
Dextromethorphan hydrobromide hydrate is an antitussive drug. |
|
| DC23104 |
D-Fagomine |
D-Fagomine (Fagomine) is a a mild glycosidase inhibitor, inhibits Amyloglucosidase (A.niger), β-Glucosidase (bovine), and Isomaltase (yeast) with Ki of 4.8 uM, 39 uM, and 70 uM, respectively. |
|
| DC22187 |
DFMO |
DFMO (Ornithine Decarboxylase inhibitor DFMO) is an irreversible inhibitor of ornithine decarboxylase (ODC), inhibits polyamine biosynthesis. |
|
| DC22074 |
DFP00173
Featured
|
DFP00173 (DFP-00173) is a potent and selective aquaporin-3 (AQP3) inhibitor, inhibits glycerol permeability in
erythrocytes with IC50 of 0.2 uM.. |
|
| DC24079 |
DG-172 dihydrochloride
Featured
|
DG-172 is a novel PPARβ/δ-selective ligand showing high binding affinity (IC50= 27 nM) and potent inverse agonistic properties. |
|
| DC20357 |
D-G23 |
D-G23 is a small molecule that inhibits RAD52-mediated ssDNA annealing with IC50 of 5.8 uM, binds to RAD52 with Kd of 34 uM and inhibits D-loop formation with IC50 of 7.2 uM in vitro. |
|
| DC23686 |
DGAT1-IN-1 |
DGAT1-IN-1 is a potent DGAT1 inhibitor with IC50 of < 10 nM.. |
|
| DC20358 |
DGAT2 inhibitor 2 |
DGAT2 inhibitor 2 is a novel potent, selective DGAT2 inhibitor with IC50 of 6 nM (hDGAT2), shows no significant activity for DGAT1 (IC50>20 uM). |
|
| DCAPI1274 |
D-glutamine |
D-glutamine is a D type stereoisomer of glutamine which is one of the 20 amino acids encoded by the standard genetic code. |
|
| DC20953 |
DH-376 |
DH-376 is a highly potent dual DAGLα/β inhibitor with IC50 of 6 nM and 3-8 nM, respectively. |
|
| DC20937 |
D-I03 |
D-I03 (D-103) is a small molecule that inhibits RAD52-mediated ssDNA annealing with IC50 of 5 uM, binds to RAD52 with Kd of 25.8 uM and inhibits D-loop formation with IC50 of 8 uM in vitro. |
|
| DC20954 |
DI-404 |
DI-404 is a highly potent, peptidomimetic inhibitor of DCN1-UBC12 protein-protein interaction that bind to DCN1 protein with Kd of 6.9 nM, selectively inhibits the neddylation of cullin 3 over other cullin members. |
|
| DC23201 |
Diarylpropionitrile
Featured
|
Diarylpropionitrile (DPN) is a non-steroidal estrogen receptor β(ERβ) selective ligand, demonstrates the neuroprotective effects against 10 0M Aβ1-42-induced oxidative stress and inflammation in primary rat cortical cell culture. |
|
| DC23747 |
Diazepinomicin |
Diazepinomicin (TLN 4601. |
|
| DC20153 |
Dibutyl phthalate
Featured
|
Dibutyl phthalate is a commonly used plasticizer commonly found in some food packaging materials, personal care products, and the coating of oral medications. May cause toxicity and adverse neurobehavioral effects. |
|
| DC8394 |
Dibutyryl-cAMP (Bucladesine)
Featured
|
Dibutyryl-cAMP (Bucladesine) is a cell-permeable PKA activator by mimicing the action of endogenous cAMP. |
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