DCC5579 |
Yml220 |
Potent and selective microbicidal agent against wild type (wt) HIV-1, NNRTI-, NRTI-, PRI-resistant mutants |
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DCC5580 |
Ynt-1310 |
Water-soluble analog of YNT-707, acting as a potent orexin 1 receptor (OX1R) antagonist |
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DCC5581 |
Ynt-707 |
Novel potent orexin 1 receptor (OX1R) antagonist |
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DCC5582 |
Yoyo-1 |
DNA-intercalating dye as sensitive amyloid probe |
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DCC5583 |
Ysy01a |
Novel Proteasome Inhibitor, Enhancing Cisplatin Cytotoxicity in Cisplatin-Resistant Human Ovarian Cancer Cells, inducing cell cycle arrest on G2 phase in MCF-7 cells via ERα and PI3K/Akt pathways |
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DCC5584 |
Yt-146 |
Selective A 2A receptor agonist |
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DCC5585 |
Yu2534342249 |
Novel γ-lactam pyrazolidinone, targeting penicillin-binding proteins (PBPs) and incorporating a siderophore moiety to facilitate uptake into the periplasm, being effective against multidrug-resistant gram-negative Bacilli |
|
DCC5586 |
Yw2065 |
Novel inhibitor of Wnt signaling by stabilizing Axin-1, a scaffolding protein that regulates proteasome degradation of β-catenin |
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DCC5587 |
Yycg Inhibitor 16 |
Novel YycG inhibitor, inhibiting planktonic cells of E. faecalis, including the vancomycin- or linezolid-resistant strains |
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DCC5588 |
Yycg Inhibitor 62 |
Novel YycG inhibitor, significantly inhibited biofilm formation in static and dynamic conditions |
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DCC5589 |
Yz-2-90 |
Novel activator of JNK, binding directly to microtubules, inducing ERK-mediated mitotic arrest and subsequent apoptosis |
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DCC5590 |
Z118332870 |
Novel first-in-class inhibitor of BRD4 and EGFR kinase |
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DCC5591 |
Z1241145220 |
Novel potent ligand of σ2 receptor (K i =7nM) |
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DCC5592 |
Z1913661252 |
Novel riboswitch activator, binding ZTP riboswitches, and activating transcription more strongly than ZMP in vitro |
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DCC5593 |
Z4446724338 |
Novel potent dual σ1/2 ligand (σ1 K i =5nM, σ2 K i =3nM), showing anti-allodynic in a model of neuropathic pain |
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DCC5594 |
Z56965384 |
Novel USP10 inhibitor |
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DCC5595 |
Zarilamide |
Inhibitor of the nuclear division in germinating zoospore cysts of Phytophthora capsici via destruction of the microtubule cytoskeleton, and a consequent inhibition of mitosis |
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DCC5596 |
Zatosetron |
Serotonin 5-HT3 receptor antagonist |
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DCC5597 |
Zbh-1205 |
Novel camptothecin derivative, revealing potent antitumor activities mainly through cell apoptosis pathway, being more effective than CPT-11 and SN38 at inhibiting topoismerase-1 |
|
DCC5598 |
Zd1611 |
Endothelin Receptor Antagonist |
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DCC5599 |
Zd2138 |
Potent, orally active inhibitor of 5-lipoxygenase (5-LO) |
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DCC5600 |
Zd6126 |
Vascular targeting agent (VTA) |
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DCC5601 |
zd6169 |
Potassium channel opener |
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DCC5602 |
Zdhhc Substrate Peptide |
ZDHHC (zinc finger Asp-His-His-Cys) substrate peptide, a 15-mer peptide sequence from KRas4a plus two tryptophan residues |
|
DCC5603 |
Zdlt-1 |
Novel potent HDAC inhibitor with IC50 values for class I HDACs 1, 2, and 3 below 4 nM, and IC50 for HDAC6 at 6 nM. |
|
DCC5604 |
Z-don-val-pro-leu-ome |
Site specific inhibitor of tissue transglutaminase |
|
DCC5605 |
Zdwx-25 |
Novel daul inhibitor of GSK-3β (IC 50 = 71 nM) and DYRK1A (IC 50 = 103 nM) with good blood-brain barrier penetrability, inhibiting hyperphosphorylation of tau protein in okadaic acid (OKA)-induced SH-SY5Y cells |
|
DCC5606 |
Zfh7116 |
Novel inhibitor of pro-HGF activation |
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DCC5607 |
Zg-2033 |
Novel Potent and Orally Bioavailable Hypoxia-Inducible Factor 2α (HIF-2α) Agonist |
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DCC5608 |
Z-ggr-amc |
Fluorogenic peptide substrate for a direct fluorometric assay of urokinase, tissue-type plasminogen activator, trypsin and thrombin |
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