| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC73887 | 4BPPNit | 4BPPNit is a small molecule significantly augmented glycosylation of α-dystroglycan, in part through upregulation of LARGE1 glycosyltransferase gene expression. |
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| DC73888 | 4-Sulfocalix[6]arene hydrate | 4-Sulfonic calix[6]arene is a potent AIM2 inflammasome inhibitor that work by binding competitively to the DNA binding site, dose dependently inhibits AIM2-dependent cell death and IL-1β release. |
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| DC73889 | 4-Sulfocalix[8]arene hydrate | 4-Sulfonic calix[8]arene is a potent AIM2 inflammasome inhibitor that work by binding competitively to the DNA binding site, dose dependently inhibits AIM2-dependent cell death and IL-1β release. |
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| DC73890 | 5M-8OH-Q Featured | 5M-8OH-Q is a specific small molecule inhibitor of UDP-glucose glycoprotein glucosyltransferase (UGGT), binds a CtUGGTGT24 “WY” conserved surface motif conserved across UGGTs (Kd=47 uM) but not present in other GT24 family glycosyltransferases. |
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| DC73891 | 7-Fluorotryptamine | 7-fluorotryptamine (7FTA) is a potent synthetic agonist of GPRC5A with EC50 of 7.2 uM for inducing GPRC5A-mediated β-arrestin recruitment. |
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| DC73892 | 7-Fluorotryptamine hydrochloride | 7-fluorotryptamine (7FTA) is a potent synthetic agonist of GPRC5A with EC50 of 7.2 uM for inducing GPRC5A-mediated β-arrestin recruitment. |
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| DC73893 | AD-5584 | AD-5584 is a potent, brain permeable human Acetyl-CoA synthetase 2 (ACSS2) inhibitor, a key metabolic enzyme involved in regulating fatty acid synthesis and protein acetylation in tumor cells. |
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| DC73894 | AD-8007 | AD-8007 is a potent, brain permeable human Acetyl-CoA synthetase 2 (ACSS2) inhibitor, a key metabolic enzyme involved in regulating fatty acid synthesis and protein acetylation in tumor cells. |
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| DC73895 | AE 51310 | AE 51310 is a small-molecule inhibitor of Opsin 4/melanopsin (OPN4), has antitumor potential in patient-derived xenograft (PDX) tumors in mice.. |
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| DC73897 | AGF347 | AGF347 (AGF-347) is a small molecule inhibitor targeting mitochondrial C1 metabolism at SHMT2 (in vitro Ki=2.19 uM), also directly targers the purine biosynthetic enzymes GARFTase (Ki=3.13 uM) and AICARFTase (Ki=3.72 uM), and SHMT1 (Ki=2.91 uM). |
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| DC73898 | AGI-25696 Featured | AGI-25696 (AGI 25696) is a potent and selective inhibitor of methionine adenosyltransferase MAT2A, blocks the growth of MTAP-deleted tumors in vivo. |
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| DC73899 | AK-3280 | AK-3280 (AK 3280, GDC 3280, RG 6069) is an orally available, potential novel anti-fibrotic small molecule under investigation for the treatment of interstitial lung diseases. |
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| DC73900 | AKST1220 | AKST1220 is a potent, specific leukotriene A4 hydrolase (LTA4H) inhibitor, improves hippocampal dependent memory. |
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| DC73901 | Alrefimotide | Alrefimotide (Telomerase reverse transcriptase 660-689 peptide antigen). |
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| DC73902 | AM9053 (AM 9053) | AM9053 (AM 9053) is a potent, selective inhibitor of N-Acylethanolamine acid amidase (NAAA) with IC50 of 30 nM, with limited effect on FAAH activity (IC50>100 uM). |
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| DC73903 | Antabactin | Antabactin (ANT) is a highly potent pan-abscisic acid (ABA) receptor antagonist with EC50 of 760 nM and picomolar dissociation constant, disrupts signaling by preventing receptor-PP2C interactions. |
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| DC73904 | AP736 | AP736 is a damantyl benzylbenzamide derivative with anti-melanogenic effects in melanocytes in vitro, acts via the downregulation of tyrosinase, TRP-1 and MITF expression. |
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| DC73905 | APC655 | APC655 is a potent activator of protein folding and unfolded protein response (UPR) modulator, APC655 activates ATF6 pathway and chaperone expression. |
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| DC73906 | AQIM-I | AQIM-I is a highly potent small molecule survivin inhibitor by targeting ILF3/NF110, binds to ILF3/NF110 with KD value of 163 nM in SPR assays, has broad-spectrum antitumor activity. |
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| DC73907 | ARL67156 | ARL67156 (FPL 67156) is a selective inhibitor of ecto-ATPase, ARL67156 is a competitive inhibitor of NTPDase1 (CD39), NTPDase3 and NPP1, with Kis of 11, 18 and 12 μM, respectively. |
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| DC73908 | ART899 | ART899 (ART-899) is a potent, specific allosteric inhibitor of DNA polymerase theta (Polθ), specifically inhibits Polθ MMEJ activity with IC50 of 180 nM, shows with improved in vivo stability compared to ART558. |
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| DC73909 | ARUK2001607 Featured | ARUK2001607 is a potent, selective and brain penetrant PI5P4Kγ inhibitor with binding KD of 7.1 nM, pIC50 of 7.1 (PI5P4Kγ+). |
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| DC73910 | ARUK200282 | ARUK200282 is a potent, isoform-selective PI5P4Kα inhibitor with pIC50 of 8.0, selective over PI5P4Kβ and PI5P4Kγ. |
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| DC73911 | ARUK2002821 | ARUK2002821 is a potent, selective PI5P4Kα inhibitor with pIC50 of 8.0, >1000-fold selective over PI5P4Kγ. |
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| DC73912 | ARUK2007145 | ARUK2007145 is a potent, selective and cell-active PI5P4Kα/γ dual inhibitor with pIC50 of 7.3/8.1, resepctively, shows no activity against PI5P4Kβ. |
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| DC73913 | ASB17061 | ASB17061 (ASB-17061) is an orally active, selective chymase inhibitor with IC50 of 0.03 uM and 0.02 uM for mMCP-4 and human chymase, respecitvely. |
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| DC73914 | ASN 90 | ASN90 is a potent, selective, substrate-competitive O-GlcNAcase (OGA) inhibitor with IC50 of 10.2 nM. |
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| DC73915 | ASP7967 | ASP7967 (ASP-7967) is a cell-permeable and low-toxic compound of RNA aptamer AC17-4 with SPR binding Kd of 12 nM, activates gene expression (>10-fold) in aptazyme-based riboswitches with EC50 of 2.3 uM. |
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| DC73916 | AZ13792138 | AZ13792138 is a highly potent, selective inhibitor of MTH1 (NUDT1) with Kd/IC50 of 0.4/0.5 nM. |
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| DC73917 | BCL3ANT | BCL3ANT (NSC-659509) is a small molecule inhibitor of Bcl-3-mediated cyclin D1 expression, reduces cyclin D1 luciferase activity in Bcl-3-overexpressing melanoma cells with IC50 of 40.4 uM. |
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