| DCAPI1495 |
Aliskiren Hemifumarate
Featured
|
Aliskiren hemifumarate(CGP 60536) is a direct renin inhibitor with IC50 of 1.5 nM. |
|
| DC23405 |
Alizapride |
Alizapride (MS 5080) is a dopamine D2 antagonist with prokinetic and antiemetic effects used in the treatment of nausea and vomiting.. |
|
| DC23489 |
Alizapride hydrochloride |
Alizapride (MS 5080) is a dopamine D2 antagonist with prokinetic and antiemetic effects used in the treatment of nausea and vomiting.. |
|
| DC23092 |
Alizarin |
Alizarin has a selective and effective inhibitory activity towards cancerous cells, it acts through the inhibition of ERK phosphorylation and cell cycle arrest in the S-phase. |
|
| DC9338 |
ALK inhibitor 1
Featured
|
ALK inhibitor 1 is a novel and selective inhibitor for the ALK kinase. |
|
| DC9339 |
ALK inhibitor 2
Featured
|
ALK inhibitor 2 is a novel and selective inhibitor for the ALK kinase. |
|
| DC10582 |
Diroximel Fumarete(ALKS-8700)
Featured
|
ALKS-8700 also known as diroximel fumarate, is a prodrug of monomethyl fumarate in a controlled-release formulation that rapidly and efficiently converts to MMF in the body. |
|
| DC11495 |
Allitinib
Featured
|
Allitinib (AST-1306, ALS1306)) is a novel potent, selective irreversible EGFR and HER2 inhibitor with IC50 of 0.5 and 3 nM in cell-free assays. |
|
| DC8106 |
ALLM (Calpain Inhibitor) |
ALLM (Calpain Inhibitor) is cell-permeable, peptide aldehyde inhibitor of calpains and cathepsins. |
|
| DC8570 |
ALLO-1
Featured
|
ALLO-1 is a SMO antagonist that inhibits both wild-type (IC50 = 50 nM) and mutant SMO, including the D473H SMO mutant (IC50s = 300-1000 nM). |
|
| DC21668 |
ALLO-2
Featured
|
ALLO-2 is a potent small molecule Smoothened (Smo) antagonist that inhibits Smo agonist Hh-Ag1.5-induced luciferase expression in TM3-Gli-Luc cells with IC50 of 6 nM. |
|
| DC12226 |
Alloepipregnanolone |
Alloepipregnanolone, a pregnane with anesthetic, hypnotic, and sedative properties, interferes with the development of rapid tolerance to the anxiolytic effect of ethanol. |
|
| DC10311 |
Allopregnanolone
Featured
|
Allopregnanolone is a progesterone metabolite. Allopregnanolone is an allosteric modulator of the GABA receptor. |
|
| DC8945 |
Allopurinol |
Allopurinol (Zyloprim) is a xanthine oxidase inhibitor with an IC50 of 7.82±0.12 μM. |
|
| DC10303 |
Allopurinol riboside |
Allopurinol riboside, a metabolite of allopurinol, shows potent activities against parasites. |
|
| DCAPI1097 |
Allopurinol Sodium (Aloprim)
Featured
|
Allopurinol sodium is a potent xanthine oxidase inhibitor (IC50 values of 0.2 to 50 μM). Allopurinol sodium can be used for the research of hyperuricemia and gout. Antileishmanial effect[1][2]. |
|
| DC20171 |
Alloxazine;Isoalloxazine |
Alloxazine is an A2 receptor antagonist, which is approximately 10-fold more selective for the A2B receptor than for the A2A receptor. |
|
| DC12060 |
all-trans-4-Oxoretinoic acid |
all-trans-4-Oxoretinoic acid, an active metabolite of vitamin A, induces gene transcription via binding to nuclear retinoic acid receptors (RARs). |
|
| DC7692 |
Almorexant HCl (Act-078573)
Featured
|
Almorexant(ACT078573) is a potent and competitive dual orexin 1 receptor (OX1)/orexin 2 receptor (OX2) antagonist with Ki values of 1.3 and 0.17 nM for OX1 and OX2, respectively. |
|
| DCAPI1478 |
Almotriptan |
Almotriptan |
|
| DC8284 |
Almotriptan Malate(PNU180638)
Featured
|
Almotriptan Malate is a 5-HT1B/1D-receptor agonist used to treat migraine. |
|
| DC11887 |
Alobresib (GS-5829)
Featured
|
Alobresib is a novel BET bromodomain inhibitor with antineoplastic activity.. |
|
| DC11931 |
Alofanib
Featured
|
Alofanib ((RPT-835) is a potent, selective, allosteric FGFR2 inhibitor that significantly inhibits bFGF-induced proliferation of HUVEC cells with IC50 of 11 nM |
|
| DCAPI1579 |
Alogliptin |
Alogliptin |
|
| DC5076 |
Alogliptin Benzoate
Featured
|
Alogliptin is an orally administered, anti-diabetic drug in the DPP-4 inhibitor class. A randomized clinical trial reporting in 2011 aimed to determine the efficacy and safety of alogliptin versus placebo and voglibose among newly diagnosed Type 2 diabete |
|
| DC10234 |
Alosetron Hydrochloride |
Alosetron Hydrochloride is the hydrochloride salt form of alosetron, a potent and selective 5-HT3 receptor antagonist. |
|
| DC10735 |
Alovudine
Featured
|
Alovudine is a DNA polymerase subunit gamma-1 (POLG) inhibitor, shows promise for treating AML. |
|
| DC9920 |
alpha-Hederin
Featured
|
alpha-hederin is a water-soluble pentacyclic triterpenoid saponin, possessing several biological properties such as antispasmodic, moliscicidic, anthelmithic and inhibiting cell proliferation. |
|
| DC23079 |
α-mangostin
Featured
|
Alpha-Mangostin has neuroprotective, anti-cancer, antifungal, neuroprotective, renoprotective, antioxidant and anti-inflammatory activities. |
|
| DC20940 |
Alprazolam |
Alprazolam (D-65MT, U 31889) is a triazolobenzodiazepine agent with anxiolytic, sedative-hypnotic and anticonvulsant activities. |
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