| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC20940 | Alprazolam | Alprazolam (D-65MT, U 31889) is a triazolobenzodiazepine agent with anxiolytic, sedative-hypnotic and anticonvulsant activities. |
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| DC26001 | Alprenolol Featured | Alprenolol is a non-selective beta blocker as well as 5-HT1A receptor antagonist. |
|
| DCAPI1328 | Alprostadil(Caverject) Featured | Alprostadil(Caverject) is a prostanoid receptor ligand, with Kis of 1.1 nM, 2.1 nM, 10 nM, 33 nM and 36 nM for mouse EP3, EP4, EP2, IP and EP1, respectively. Prostaglandin E1 induces vasodilation and inhibits platelet aggregation. Prostaglandin E1 can be used as a vasodilator for the research of peripheral vascular diseases. |
|
| DC12656 | Alrestatin Featured | Alrestatin is an AKR (aldose reductase) inhibitor, which attaches molecules to the active site of the NADP+/enzyme complex in a stacked formation. |
|
| DC8366 | ALS22335 Featured | ALS-22335 is an anti-virus compound. |
|
| DC23098 | ALS-8112 | ALS-8112 is a potent, selective RSV polymerase inhibitor, the 5'-triphosphate of ALS-8112 (ALS-8112-TP) inhibits RSV polymerase(IC50=20 nM) without appreciable inhibition of human DNA and RNA polymerases. |
|
| DC23144 | ALS-8176 | ALS-8176 (Lumicitabine) is the 3',5'-di-O-isobutyryl prodrug of ALS-8112 5'-triphosphate (ALS-8112-TP), which is a potent, selective RSV polymerase inhibitor with IC50 of 20 nM. |
|
| DC9838 | Alsterpaullone Featured | Alsterpaullone is a potent ATP-competitive and cell cycle cyclin-dependent kinase inhibitor, that is reported to be the most active Paullone. |
|
| DC8072 | Altiratinib(DCC-2701) Featured | Altiratinib is a MET/TIE2/VEGFR2/TRK (A,B,C) kinase inhibitor in Phase 1 clinical development for the treatment of invasive solid tumors including glioblastoma. |
|
| DCAPI1290 | Altretamine (Hexalen) | Altretamine (Hexalen) |
|
| DC7079 | Alvelestat (AZD9668) Featured | Alvelestat (AZD9668) is a novel, oral inhibitor of neutrophil elastase (NE) with the pIC50 of 7.9 for Human NE. |
|
| DCAPI1250 | Alverine Citrate | Alverine citrate is a drug used for functional gastrointestinal disorders. |
|
| DC8606 | Alvimopan monohydrate | Alvimopan(LY 246736; ADL 8-2698) is a peripherally acting mu-opioid receptor (PAM-OR, IC50= 1.7 nM) antagonist for accelerating gastrointestinal recovery after surgery. |
|
| DC8605 | Alvimopan dihydrate | Alvimopan(LY 246736; ADL 8-2698) is a peripherally acting mu-opioid receptor (PAM-OR, IC50= 1.7 nM) antagonist for accelerating gastrointestinal recovery after surgery. |
|
| DC10209 | ALW-II-41-27 Featured | ALW-II-41-27 is a novel Eph receptor tyrosine kinase inhibitor, used for cancer treatment. |
|
| DC23849 | ALW-II-49-7 | ALW-II-49-7 (DDR2-IN-1) is a potent, selective DDR2 inhibitor with IC50 of 18.6 nM, also shows ability to inhibit DDR1 and Ephrin-family kinases (IC50=40 nM for EphB2). |
|
| DC11840 | ALX-1393 | ALX-1393 (ALX 1393, ALX1393) is a potent, specific GlyT2 inhibitor with Ki of <1 uM. |
|
| DC23604 | ALX-5407 hydrochloride Featured | ALX-5407 is a potent, selective, orally active inhibitor of GlyT1 glycine transporter with IC50 of 3 nM. |
|
| DC11301 | ALZ-801 Featured | ALZ-801 is a potent and orally available small-molecule β-amyloid (Aβ) anti-oligomer and aggregation inhibitor, valine-conjugated prodrug of Tramiprosate with substantially improved PK properties and gastrointestinal tolerability compared with the parent compound. ALZ-801 is an advanced and markedly improved candidate for the treatment of alzheimer’s disease. |
|
| DC22431 | AM432 sodium | AM 432 is potent, selective, orally active prostaglandin D2 receptor (DP2/CRTH2) antagonist with binding IC50 of 6 nM for hDP2. |
|
| DC11182 | AM-0216 | AM-0216 (Amgen16) is a highly potent inhibitor of NF-κB inducing Kinase (NIK) with Ki of 2 nM, selectively decrease viability of MMCLs in which NFkB activity is NIK-dependent. |
|
| DC11289 | AM-0466 Featured | AM-0466 is a potent and selective NaV1.7 Inhibitor (Nav 1.7 IC50 = 21 nM; Nav 1.5 IC50 =>30.0 uM. PXR = 22% @10 uM; CYP 2C9 IC50 = 4.6 uM; CYP3A4 TDI IC50 =>50.0 uM.). |
|
| DC11181 | AM-0561 | AM-0561 (AM0561) is a highly potent inhibitor of NF-κB inducing Kinase (NIK) with Ki of 0.3 nM.. |
|
| DC8621 | AM095 Featured | AM095 is a potent LPA1 receptor antagonist with IC50 values of 0.98 and 0.73 μM for recombinant human or mouse LPA1 respectively. |
|
| DC8622 | AM095 free acid Featured | AM095 is a potent LPA1 receptor antagonist with IC50 values of 0.98 and 0.73 μM for recombinant human or mouse LPA1 respectively. |
|
| DC9909 | AM2099 Featured | AM-2099 is a potent and selective NaV1.7 Inhibitor. |
|
| DC12230 | AM211 Featured | AM211 is a potent, selective and orally bioavailable prostaglandin D2 (PGD2) receptor type 2 (DP2) antagonist |
|
| DC9830 | AM-2394 Featured | AM-2394 is a potent and selective Glucokinase agonist (GKA), which catalyzes the phosphorylation of glucose to glucose-6-phosphate. |
|
| DC8765 | AM251 Featured | AM251 is a potent CB1 receptor antagonist (IC50 = 8 nM, Ki = 7.49 nM) that displays 306-fold selectivity over CB2 receptors; also potent GPR55 agonist (EC50 = 39 nM). |
|
| DC23485 | AM-5262 | AM-5262 is a potent full GPR40 (FFA1) agonist with EC50 of 81 nM. |
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