| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC8762 | BMS-265246 | BMS-265246 is a potent and selective CDK1/2 inhibitor for CDK1/cyclin B and CDK2/cyclin E with IC50 of 6 nM and 9 nM, respectively. |
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| DC8513 | BMS-3 Featured | BMS-3 is a potent inhibitor of the LIM kinase. It has IC50's of 5nM and 6 nM for LIMK1 and LIMK2 respectively. |
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| DC7375 | BMS-303141 Featured | BMS-303141 is a potent ATP-citrate lyase (ACL) inhibitor with IC50 value of 0.13 uM (human recombinant ACL). |
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| DC8457 | BMS-309403 Featured | BMS309403 is orally active, reducing atherosclerosis in mice lacking apoplipoprotein E. |
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| DC20808 | BMS-394136 | BMS-394136 is a potent, selective IKur/Kv1.5inhibitor, increases atrial action potential duration (APD) and prolongs AERP but not VERP in both rabbits and beagles.. |
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| DC20809 | BMS433771 | BMS433771 is a potent, orally active RSV fusion inhibitor, exhibits excellent potency against multiple laboratory and clinical isolates of both group A and B viruses with mean EC50 of 20 nM. |
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| DC23529 | BMS-457 | BMS-457 is a potent and selective CCR1 antagonist with binding IC50 of 0.8 nM, >1,000-fold selectivity against other CC family receptors. |
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| DC5037 | BMS-536924 Featured | BMS-536924 is an ATP-competitive IGF-1R inhibitor with IC50 of 100 nM, modest activity for Mek, Fak, and Lck with very little activity for Akt1, MAPK1/2. |
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| DC7007 | BMS-538203 | BMS-538203 is a highly efficient HIV integrase inhibitor and antiviral agent. |
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| DC23167 | BMS-564929 | BMS-564929 is a potent, selective androgen receptor modulator (SARM) that binds to AR with Ki of 2.11 nM. |
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| DC7897 | BMS-582949 HCl Featured | BMS-582949 is a dual action p38 Kinase Inhibitor. |
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| DC22033 | BMS-595 | BMS-595 (BMS595) is a novel potent, selective, ATP-competitive casein kinase 2 (CK2) inhibitor with IC50 of 1.3 nM (CKα). |
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| DC24131 | BMS-599626 hydrochloride | BMS-599626 (AC-480) is a potent, selective inhibitor of EGFR and HER2 with IC50 of 20 nM and 30 nM. |
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| DC3105 | BMS-599626 (AC480) Featured | BMS-599626 (AC480) is a selective and efficacious inhibitor of HER1 and HER2 with IC50 of 20 nM and 30 nM, respectively. |
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| DC7730 | Temsavir（BMS-626529） Featured | BMS-626529 is a novel small-molecule attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4+ T-cells. |
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| DC20805 | BMS-641988 | BMS-641988 is a potent, selective, nonsteroidal androgen receptor antagonist with Ki of 1.7 nM, MDA-MB-453 cell IC50 of 16 nM. |
|
| DC20811 | BMS-654457 | BMS-654457 is a potent, reversible and direct inhibitor of factor XIa (FXa) with Ki of 0.4 nM. |
|
| DC9252 | BMS-687453 Featured | BMS687453 is a potent and selective peroxisome proliferator activated receptor (PPAR) α agonist, with an EC50 of 10 nM for human PPARα and ∼410-fold selectivity vs human PPARγ in PPAR-GAL4 transactivation assays. |
|
| DC22034 | BMS-699 | BMS-699 (BMS699) is a novel potent, selective, ATP-competitive casein kinase 2 (CK2) inhibitor with IC50 of 0.1 nM (CKα). |
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| DC9700 | BMS-707035 Featured | BMS-707035 is a potent, specific, and reversible HIV-I integrase (IN) inhibitor that blocks HIV IN strand transfer activity. |
|
| DC3114 | Avagacestat (BMS-708163) Featured | BMS-708163 is a potent, selective γ-secretase inhibitor of Aβ40 and Aβ42 with IC50 of 0.3 nM and 0.27 nM, respectively. |
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| DC23482 | BMS-741672 | BMS-741672 is a potent, selective CCR2 antagonist for the treatment of neuropathic pain.. |
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| DC20813 | BMS-751324 | BMS-751324 is a novel clinical prodrug of BMS-582949, which is a highly selective p38α MAPK inhibitor with IC50 of 13 nM. |
|
| DC3126 | BMS754807 Featured | BMS-754807 is a potent and reversible inhibitor of IGF-1R/IR family kinases, inhibits IGF-1R, IR, Met, TrkA and TrkB with IC50 of 1.8 nM, 1.7 nM, 5.6 nM, 7.4 nM and 4.1 nM, respectively. |
|
| DC9861 | BMS-779788(XL-652) Featured | BMS-779788(XL652) is a novel small-molecule modulator of the Liver X Receptor (LXR), a nuclear hormone receptor implicated in a variety of cardiovascular and metabolic disorders. |
|
| DC9638 | BMS-794833 | BMS-794833 is a potent ATP competitive inhibitor of Met/VEGFR2 with IC50 of 1.7/15 nM; also inhibits Ron, Axl and Flt3 with IC50 of <3 nM; a prodrug of BMS-817378. |
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| DC20814 | BMS-795311 | BMS-795311 is a potent and orally available CETP inhibitor with IC50 of 3.8 nM, inhibits cholesteryl ester (CE) transfer with IC50 of 0.22 uM. |
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| DC7089 | BMS-806 (BMS 378806) | BMS-806 (BMS 378806) is a small molecule gp120/CD4 inhibitor with an IC50 of median 5 nM. |
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| DC10494 | BMS813160 Featured | BMS-813160 is a dual CCR2/CCR5 chemokine antagonist. |
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| DC12670 | BMS-817378 free base Featured | BMS-817378 is a prodrug of the dual Met/VEGFR-2 inhibitor BMS-794833. |
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