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Cat. No. Product Name Field of Application Chemical Structure
A104 Bemarituzumab Biosimilar(Anti-FGFR2 / CD332 Reference Antibody) Featured Bemarituzumab is a first-in-class, humanized IgG1 monoclonal antibody against FGFR2b (a FGF receptor). Bemarituzumab blocks fibroblast growth factors from binding and activating FGFR2b. Bemarituzumab has the potential for cancer research.
A105 Vofatamab Biosimilar(Anti-FGFR3 / CD333 Reference Antibody ) Featured Vofatamab (B-701) is an anti-FGFR3 monoclonal antibody (mAb). Vofatamab blocks activation of both the wildtype and genetically activated receptor. Vofatamab can be used in the research of metastatic urothelial carcinoma (mUC).
A106 U3-1784 Biosimilar(Anti-FGFR4 / CD334 Reference Antibody) Featured
A107 Radretumab Biosimilar(Anti-Fibronectin Reference Antibody) Featured
DC66691 L19TNF Featured
A109 Rosopatamab Biosimilar(Anti-FOLH1 / PSMA Reference Antibody) Featured Rosopatamab (HuJ591) is a humanized antiPSMA IgG1 monoclonal antibody that can be used in cancer research, especially prostate cancer. Rosopatamab can be linked to the low-energy beta-emitting radioisotope lutetium-177 (177Lu) through the bifunctional chelator DOTA-NHS ester to obtain a radioimmunoconjugate that targets malignant prostate cells with high efficiency.
A110 Pelgifatamab Biosimilar(Anti-FOLH1 / PSMA Reference Antibody) Featured Pelgifatamab (BAY-2315497) is a prostate-specific membrane antigen (PSMA) antibody. Pelgifatamab can be covalently linked to a binding moiety of 225Ac and used for metastatic castration-resistant prostate cancer (mCRPC) research.
A111 Mirvetuximab Biosimilar(Anti-FOLR1 / FRA Reference Antibody) Featured Mirvetuximab (M9346A) is an anti-FOLR1 (folate receptor 1) monoclonal antibody. Mirvetuximab is the antibody moiety of novel folate receptor alpha (FRα)-targeting ADC (Mirvetuximab soravtansine). Mirvetuximab soravtansine can be used in ovarian and other FRα-positive cancer research.
DC66695 Cofrogliptin Featured Cofrogliptin (HSK7653) (compound 2), a tetrahydropyran derivative, is a potent oral dipeptidyl aminopeptidase 4 (DPP-4) inhibitor with Long-acting antidiabetic efficacy. Cofrogliptin (compound 2) has a great potential for type 2 diabetes mellitus (T2DM) .
DC66696 (R)-2-Thioxothiazolidine-4-carboxylic acid-13C3 Featured (R)-2-Thioxothiazolidine-4-carboxylic acid-13C3 is the 13C-labeled (R)-2-Thioxothiazolidine-4-carboxylic acid. Radioactive isotopes labeled compounds can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified.
DC66697 2-Thioxothiazolidine-4-carboxylic Acid Featured
DC66698 STING agonist-12 Featured STING agonist-12 (Compound 53) is a potent, orally active human STING activator with an EC50 of 185 nM.
A619 Sacituzumab govitecan Featured Sacituzumab govitecan (IMMU-132) is an antibody-drug conjugate (ADC) targeting Trop-2 for delivery of SN-38. Sacituzumab govitecan shows anticancer activity.
DC66700 (S,R)-LSN3318839 Featured (S,R)-LSN3318839 is the stereoisomer of LSN3318839 (HY-142162). LSN3318839 is an orally active positive allosteric modulator of the glucagon-like peptide-1 receptor (GLP-1R).
DC66701 (3R,5S)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)pyrrolidin-3-ol Featured
A112 Farletuzumab Biosimilar(Anti-FOLR1 / FRA Reference Antibody) Featured Farletuzumab (MORAb-003) is a potent folate receptor-alpha (FRα) inhibitor. Farletuzumab is a humanized monoclonal antibody with high affinity for FRα. Farletuzumab possesses growth-inhibitory functions on cells overexpressing FRα. Farletuzumab can be used in research of cancer.
A114 Dompe patent anti-FOLR1 Biosimilar(Anti-FOLR1 / FRA Reference Antibody) Featured
A116 BMS-986012 Biosimilar(Anti-Fucosyl GM1 Reference Antibody) Featured
A130 Vantictumab Biosimilar(Anti-FZD Reference Antibody) Featured Vantictumab (OMP-18R5) is a fully human IgG2 monoclonal antibody. Vantictumab inhibits Wnt pathway signaling by binding to FZD1/2/5/7/8 receptors. Vantictumab is being studied against cancers such as metastatic HER2-negative breast cancer and metastatic pancreatic adenocarcinoma.
A131 U.Toronto patent anti-FZD7 Biosimilar(Anti-FZD7 Reference Antibody) Featured
DC60641 CD-005 Featured CD-005 is a low-molecular-weight gelator that can be used to prepare gels for proteins and vaccines. CD-005 can physically entrap proteins, preventing their irreversible aggregation, and maintain protein function for at least 4 weeks even at temperatures up to 50°C.
DC66707 Casdatifan Featured Casdatifanum is a hypoxia-inducible factor (HIF) inhibitor.
DC66708 BMS-986408 Featured BMS-986408 is a DGK inhibitor.
DC66709 BAY-2925976 Featured BAY-2925976 is an ARα2C antagonist.
DC66710 AZD4144 Featured AZD4144 is an NLRP3 inhibitor.
DC66711 CHF-6523 Featured CHF-6523 is an inhaled PI3Kδ inhibitor.
DC66712 BAY-2413555 Featured
DC66713 NVP-EVS459 Featured
DC60642 Compound 33 (HYOU1 inhibitor) Featured Compound 33 (HYOU1 inhibitor) is a first-in-class inhibitor of hypoxia up-regulated protein 1 (HYOU1) with EC50 of 3.2 μM/2.6 μM/16.1 μM/3.0 μM in WT-MIP3/WT-RANTES/hTNFtg-MIP3/hTNFtg-RANTES, respectively.
DC60643 BRD-810 Featured BRD-810 is a potent and selective MCL1 inhibitor with Kd of 0.3 nM (SPR) and IC50 of 0.4 nM (MCL1-Noxa HTRF), respectively. BRD-810 is a rapidly cleared inhibitor of MCL1 that has robust antitumor efficacy in hematological and solid tumor cancer models.

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