| A514 |
Romosozumab Biosimilar（Anti-SOST / Sclerostin Reference Antibody）
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Romosozumab is a humanized monoclonal anti-sclerostin antibody, it promotes bone formation and inhibits bone resorption by inhibiting sclerostin. Romosozumab can be used for the research of osteoporosis. |
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| A515 |
Sonepcizumab Biosimilar（Anti-Sphingosine-1-phosphate Reference Antibody）
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Sonepcizumab (LT 1009) is a fully human anti-S1P monoclonal antibody. Sonepcizumab has the potential for the research of metastatic renal cell carcinoma (mRCC). |
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| A516 |
Expression DD patent anti-SIP Biosimilar（Anti-Sphingosine-1-phosphate Reference Antibody）
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| A517 |
Bexmarilimab Biosimilar（Anti-STAB1 Reference Antibody）
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Bexmarilimab (FP-1305) is a potent humanized anti-CLEVER-1 IgG4-antibody with an IC50 value of 4.51 nM. Bexmarilimab is capable of inducing a phenotypic M2 to M1 immune switch of tumor-associated macrophages. Bexmarilimab can be used in research of cancer. |
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| A518 |
vandortuzumAb Biosimilar（Anti-STEAP1 Reference Antibody）
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| A519 |
Genentech patent anti-STOP-1 Biosimilar（Anti-STOP1 Reference Antibody）
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| A520 |
Indatuximab Biosimilar（Anti-Syndecan-1 / CD138 Reference Antibody）
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| A521 |
Genentech patent anti-TAT226 Biosimilar（Anti-TAT226 Reference Antibody）
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| A522 |
Zagotenemab Biosimilar（Anti-Tau Reference Antibody）
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Zagotenemab (LY3303560) is a humanised anti-tau antibody that selectively binds and neutralises tau deposits in the brain. Zagotenemab can be used in Alzheimer's disease research. |
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| A523 |
Tilavonemab Biosimilar（Anti-Tau Reference Antibody）
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Tilavonemab (ABBV-8E12) is a humanized anti-tau antibody that targets the extracellular form of pathological tau protein aggregates by binding to the N-terminal 25-30 amino acid residues of tau protein. Tilavonemab blocks the ability of human and mouse neurons to take up tau aggregates, reduces the loss of brain volume, slows the progression of tau pathology, and improves cognitive abilities in transgenic mice expressing mutant human tau. Tilavonemab is used in Alzheimer's disease research. |
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| A524 |
Semorinemab Biosimilar（Anti-Tau Reference Antibody）
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Semorinemab (RG 6100) is an anti-Tau humanized IgG4 monoclonal antibody, targets the N-terminal portion of the Tau protein (amino acid residues 6-23). Semorinemab binds with human Tau with a Kd value of 3.8 nM. Semorinemab can be used for the research of Alzheimer's Disease. |
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| A525 |
Bepranemab Biosimilar（Anti-Tau Reference Antibody ）
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Bepranemab (UCB 0107) is a humanized, full-length IgG4 monoclonal antibody that binds to a central tau epitope (amino acids 235-250). Bepranemab can be used for Alzheimer’s disease (AD) research. |
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| A526 |
Gosuranemab Biosimilar（Anti-Tau Reference Antibody）
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Gosuranemab (BMS-986168) is a humanised IgG4 anti-tau monoclonal antibody. Gosuranemab binds to human N-terminal tau residues 15-22. Gosuranemab has the potential for the research of alzheimer’s disease (AD). |
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| A527 |
LY3022859 Biosimilar（Anti-TBFbR2 Reference Antibody）
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| A528 |
TOL101 Biosimilar（Anti-TCR Reference Antibody）
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| A529 |
NKTT320 Biosimilar（Anti-TCR Reference Antibody）
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| A530 |
Ontuxizumab Biosimilar（Anti-TEM1 / Endosialin / CD248 Reference Antibody）
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Ontuxizumab (MORAb-004) is a humanized IgG1/κ anti-endosialin (TEM-1 or CD248) monoclonal antibody with antitumor effects. Ontuxizumab can be used for the research of cancer. |
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| A531 |
Fox Chase patent anti-TEM7R Biosimilar（Anti-TEM7R / PLXDC2 Reference Antibody）
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| A532 |
Tenatumomab Biosimilar(Anti-Tenascin C Reference Antibody)
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Tenatumomab (ST2146) is a murine monoclonal antibody against tenascin-C. And tenascin-C, the large extracellular glycoprotein, is overexpressed in cancer. Tenatumomab has been used for Pretargeted Antibody Guided Radioimmunoresearch (PAGRIT), and delivering radionuclides to tumors via PAGRIT and direct 131Iodine labeling approach. |
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| A533 |
Marstacimab Biosimilar(Anti-TFPI Reference Antibody)
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Marstacimab (PF-06741086) is an anti-tissue factor pathway inhibitor (TFPI) monoclonal antibody. Marstacimab can be used for the research of hemophilia. |
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| A534 |
Befovacimab Biosimilar(Anti-TFPI Reference Antibody)
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Befovacimab (BAY 1093884) is a fully human monoclonal IgG2 antibody able to bind to tissue factor pathway inhibitor (TFPI). Befovacimab can be used for haemophilia A/B research. |
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| A535 |
Jr-141 Biosimilar(Anti-TfR Reference Antibody)
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Pabinafusp alfa (JR-141) is a transferrin receptor-targeting antibody consisting of Iduronate 2-sulfatase (HY-P76399) and an anti-human transferrin receptor antibody. Pabinafusp alfa is blood-brain permeable and prevents heparan sulfate (HS) deposition in the central nervous system of mucopolysaccharidosis II (MPS II) mice. Pabinafusp alfa improves learning and prevents central nervous system neuronal damage in mice. |
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| A536 |
SRK181 Biosimilar（Anti-TGFb1 Reference Antibody）
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| A537 |
Fresolimumab Biosimilar（Anti-TGFb1 Reference Antibody）
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Fresolimumab (GC1008) is a human monoclonal antibody against TGF-β that neutralizes all mammalian active subtypes of TGF-β. The binding affinity of Fresolimumab to TGF-β2 is 1.8 nM. Fresolimumab radiolabeled with 89Zr can be used for PET analysis of TGF-β expression, antibody uptake and organ distribution. Fresolimumab can be used in the study of cancer, osteogenesis imperfecta, fibrosis and kidney disease. |
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| A538 |
M7824 Biosimilar（Anti-TGFb1 Reference Antibody）
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Bintrafusp alfa (M 7824) is a first-in-class bifunctional fusion protein composed of the extracellular domain of TGF-βRII fused to a human IgG1 mAb blocking programmed cell death ligand. Bintrafusp alfa can be used for the research of cancer. |
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| A539 |
Nisevokitug Biosimilar（Anti-TGFb1 Reference Antibody）
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Nisevokitug (NIS-793) is a human, IgG2λ antibody targeting TGF-β (TGFB1/TGFB2). Nisevokitug is expressed by CHO-K1 cells. |
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| A540 |
Genzyme patent anti-TGF-β Biosimilar（Anti-TGFb1 Reference Antibody）
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| A541 |
Zampilimab Biosimilar（Anti-TGM2 / Transglutaminase 2 Reference Antibody）
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Zampilimab (UCB-7858) is a monoclonal antibody against transglutaminase 2 (TG2). Zampilimab has potential application in renal transplant. |
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| A542 |
Regeneron patent anti-TIE-2 Biosimilar（Anti-TIE2 / CD202b Reference Antibody）
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| A543 |
Tiragolumab Biosimilar（Anti-TIGIT Reference Antibody）
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Tiragolumab is an immune checkpoint inhibitor binding to T-cell immunoglobulin and ITIM domain (TIGIT). Tiragolumab, alone or in combination with the PD-L1 inhibitor Atezolizumab (HY-P9904), may be effective against multiple solid malignancies-most notably non-small cell lung cancer (NSCLC). |
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