| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC7543 | Bromosporine Featured | Bromosporine is a broad spectrum bromodomain inhibitor. Accelerates FRAP recovery of BRD4 and CREBBP in cells at a concentration of 1 μM. |
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| DC12633 | Bromotriazine | Bromotriazine (BTZ) is a covalent probe against bromodomain containing proteins with selectively targeting non-catalytic, highly conserved amino acid residues.. |
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| DC9141 | Brompheniramine hydrogen maleate | Brompheniramine maleate is a histamine H1 receptors antagonist. |
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| DC23385 | BRPF1B TRIM24-IN-34 | BRPF1B TRIM24-IN-34 is a selective BRPF1B/TRIM24 dual inhibitor that binds with KD of 137 and 222 nM, respectively. |
|
| DC10913 | Brusatol | Brusatol (NSC 172924, (+)-Brusatol) is a quassinoid extracted from Brucea Esters, can inhibit HIF-1 signaling pathway, also is a potent Nrf2 inhibitor. |
|
| DC11038 | Bryostatin 1 Featured | Bryostatin 1 (NSC 339555) is a macrocyclic lactone derived from a marine invertebrate, fuctions as an activator of PKC with high binding affinity (Ki=1.35 nM). |
|
| DC10954 | BS148 | BS148 (BS-148) is a potent, selective σ2 receptor agonist with pKi of 7.71, displays 25-fold selectivity over σ1. |
|
| DC9846 | BS-181 Featured | BS-181 is a highly selective CDK7 inhibitor with IC50 of 21 nM. ; >40-fold selective for CDK7 than CDK1, 2, 4, 5, 6, or 9. |
|
| DC8101 | BS-181 hydrochloride Featured | BS-181 is a highly selective CDK7 inhibitor with IC50 of 21 nM. ; >40-fold selective for CDK7 than CDK1, 2, 4, 5, 6, or 9. |
|
| DC8517 | BS194 Featured | BS-194 is a selective and potent CDK inhibitor, which inhibits CDK2, CDK1, CDK5, CDK7, and CDK9 with IC50 values of 3, 30, 30, 250, and 90 nM respectively. |
|
| DC7378 | BSI-201 | BSI-201 (Iniparib; NSC-746045) is a PARP1 inhibitor with demonstrated effectiveness in triple-negative breast cancer (TNBC). |
|
| DC12380 | BSJ-03-123 Featured | BSJ-03-123 is a potent, CDK6-selective small-molecule degrader (PROTAC) that uniquely enables rapid pharmacological interrogation of CDK6-dependent functions. |
|
| DC10460 | BT-11 Featured | BT-11 is an orally active and selective LANCL2 modulator. |
|
| DC10164 | BTB-1 Featured | BTB-1 is a small molecule inhibitor of the mitotic motor protein Kif18A. |
|
| DC20199 | BTK inhibitor 1;Compound 27 Featured | BTK inhibitor 1 (Compound 27) |
|
| DC26026 | Btk inhibitor 2 | Btk inhibitor 2 is a Bruton's tyrosine kinase (BTK) inhibitor extracted from patent US 20170224688 A1. |
|
| DC12432 | BTK inhibitor 4b | BTK inhibitor 4b is a potent, highly selective inhibitors of BTK with IC50 of 4.2 and 0.9 nM against activated and unactivated BTK, respectively. |
|
| DC11065 | BTK PROTAC 10 | BTK PROTAC 10 is a novel potent PROTAC for BTK with DC50 of 1.1 nM in cultured Ramos cells. |
|
| DC11064 | BTK PROTAC 9 | BTK PROTAC 9 is a novel potent PROTAC for BTK with DC50 of 5.9 nM in cultured Ramos cells, requires simultaneous engagement of BTK and CRBN to effectively degrade BTK. |
|
| DC11431 | BTK-030 | BTK-030 is a novel BTK inhibitor. |
|
| DC23870 | BTK-IN-23 | BTK-IN-23 is a highly potent and selective Btk inhibitor with IC50 of 3 nM. |
|
| DC23413 | BTRX335140 Featured | BTRX-335140 (CYM-53093, BTRX335140, CYM53093) is a potent, selective, orally active κ opioid receptor (KOR) antagonist with IC50 of 0.8 nM. |
|
| DC12456 | BTT-266 Featured | BTT-266 (BTT266) is a voltage-gated CaV2.2 calcium channel inhibitor that disrupts the CaVα·CaVβ3 protein-protein interaction, directly binds to CaVβ3 with Kd of 3.6 uM. |
|
| DC12457 | BTT-369 | BTT-369 (BTT369) is a voltage-gated CaV2.2 calcium channel inhibitor that disrupts the CaVα·CaVβ3 protein-protein interaction with Ki of 2.0 uM in FP assays. |
|
| DC11252 | BTX161 | BTX161 is a thalidomide analog that mediates degradation of CKIα better than lenalidomide in human AML cells and activates DDR and p53, while stabilizing the p53 antagonist MDM2. |
|
| DC23703 | BTYNB Featured | BTYNB is a potent and selective inhibitor of IMP1 binding to c-Myc mRNA with IC50 of 5 uM. |
|
| DC9704 | Unii-G55ZH52P57 Featured | BTZ043 is a inhibitor of decaprenyl-phosphoribose-epimerase (DprE1), It can display nanomolar bactericidal activity against Mycobacterium tuberculosis in vitro. |
|
| DCAPI1392 | BTZ043 racemate Featured | BTZ043 racemate is a decaprenylphosphoryl-β-D-ribose 2-epimerase (DprE1) inhibitor acting as a new antimycobacterial agent that kill Mycobacterium tuberculosis. |
|
| DC22041 | BTZO-1 Featured | BTZO-1 is a cardioprotective agent and Macrophage migration inhibitory factor (MIF) activator, binds to MIF with Kd of 68.6 nM, regulates ARE-mediated gene expression. |
|
| DC22042 | BTZO-15 | BTZO-15 is an active BTZO-1 derivative for ARE-activation with a favorable ADME-Tox profile, induces expression of heme oxygenase-1 (HO-1) and inhibits NO-induced cell death in IEC-18 cells. |
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