| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC10432 | CDD3506 | CDD3506 is used for elevating high density lipoprotein cholesterol (HDL) by inducing hepatic cytochrome P450IIIA (CYP3A) activity. |
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| DC22051 | CDD-450 | CDD-450 is an unique inhibitor that selectively blocks p38α activation of proinflammatory kinase MAPK-MK2 while sparing p38α activation of PRAK and ATF2. |
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| DC8361 | CDDO(Bardoxolone; RTA 401) Featured | CDDO is a synthetic oleanane triterpenoid that blocks the cellular synthesis of inducible nitric oxide synthase and inducible COX-2 in INF-γ-activated mouse macrophages with an IC50 value of 0.4 nM. |
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| DC12026 | CDDO-2P-Imidazolide Featured | CDDO-2P-Im is a new analogue of CDDO-Imidazolid,showing better bioactive than CDDO-Imidazolid. |
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| DC12027 | CDDO-3P-Imidazolide Featured | CDDO-3P-Im is a new analogue of CDDO-Imidazolid,showing better bioactive than CDDO-Imidazolid. |
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| DC12025 | CDDO imidazolide Featured | CDDO-imidazolide is a potent inducer of heme oxygenase-1 and Nrf2/ARE signaling,with potent antiproliferative, differentiating, and anti-inflammatory activities. |
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| DC9277 | C-DIM12 Featured | C-DIM12 is a novel synthetic activator of Nurr1. |
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| DC10792 | DIM-C-pPhOCH3(C-DIM5) Featured | C-DIM5 is a Nur77 agonist. Activation of the orphan nuclear receptor Nur77 by C-DIM5 is associated with decreased cancer cell survival, |
|
| DC11158 | CDK12 inhibitor 2 | CDK12 inhibitor 2 is a potent, selective, non-covalent CDK12 inhibitor with IC50 of 52 nM, displays >192-fold selectivity over CDK2/7/8/9. |
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| DC11872 | CDK12 inhibitor E9 S-isomer | CDK12 inhibitor E9 S-isomer (E9, CDK12-IN-E9) is a clinical analog of THZ1 and a selective, covalent CDK12 inhibitor that is not susceptible to ABC transporter-mediated drug efflux. |
|
| DC20334 | CDK2 inhibitor 73 Featured | CDK2 inhibitor 73 is a potent, selective CDK2 inhibitor with IC50 of 44 nM for CDK2/cyclin A, displays 2,000-fold selectivity over CDK1/cyclin B (IC50=86 uM).. |
|
| DC8596 | Cdk4/6 Inhibitor IV | Cdk4/6 Inhibitor IV is a cell-permeable triaminopyrimidine compound acting as a reversible and ATP-competitive inhibitor of Cdk4/6 (IC50 = 1.5 µM and 5.6 µM for Cdk4/D1 and Cdk6/D1, respectively) |
|
| DC20921 | CDK5 inhibitor 20-223 | CDK5 inhibitor 20-223 (CP 668863) potent, selective, ATP-competitive CDK2/5 inhibitor with IC50 of 6.0 and 8.8 nM for CDK2/CyclinE and CDK5/p35, with little to no activity against CDK1/4/6/7/9. |
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| DC12528 | CDK9 inhibitor HH1 Featured | CDK9 inhibitor HH1 is a novel potent, highly selective CDK9 inhibitor.. |
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| DC20335 | CDK9-IN-8 Featured | CDK9-IN-8 is a highly potent, selective CDK9 inhibitor with IC50 of 12 nM, shows good selectivity in CDKs kinase profiling assay against CDK kinases and cell proliferation inhibition. |
|
| DC9478 | CDK9-IN-1 | CDK9-IN-1 is a novel, selective CDK9 inhibitor for the treatment of HIV infection. |
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| DC23138 | CDK-I73 Featured | CDKI-73 is a potent CDK9 inhibitor with Ki of 4 nM, shows cytotoxicity against a broad CLL samples with mean LD50 of 80 nM. |
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| DC9390 | CDK-IN-2 Featured | CDK-IN-2 is a potent and sepecific CDK inhibitor. |
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| DC11393 | CDM-NAG Featured | CDM-NAG is a useful tool compound to deliver the siRNA. |
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| DC10948 | CDN1163 Featured | CDN1163 (CDN-1163) is a small molecule, allosteric activator of SERCA2, dose-dependently increases the Vmax of SERCA2 Ca2+-ATPase activity in ER microsomes; increases Ca2+-ATPase activity and significantly enhances Ca2+ uptake into the ER, attenuates H2O2-stimulated cell death in HEK cells; improves glucose homeostasis and metabolic parameters, increases glucose tolerance in ob/ob mice; CDN1163 reduces lipid accumulation and decreases lipogenesis in obese mice livers. |
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| DC20879 | CDP-840 | CDP-840 (CDP840. |
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| DC20880 | CDP-840 hydrochloride | CDP-840 (CDP840. |
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| DC23463 | CDPPB Featured | CDPPB is a potent, selective, brain penetrant positive allosteric modulator of mGlu5 receptor with EC50 of 10 nM and 20 nM for human and rat mGluR5, respectively. |
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| DC22446 | CE-224535 | CE-224535 (PF-04905428) is a potent and selective P2X7 receptor antagonist with IC50 of 1.4 nM (inhibition of the release of lL-1b from monocytes stimulated by ATP). |
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| DC20881 | CE-245677 | CE-245677 is a potent, selective, orally active, dual Tie2/Trk kinase inhibitor with IC50 of 4.7 nM, 1 nM for Tie2 and TrkA/B, respectively. |
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| DC20336 | CE3F4 Featured | CE3F4 is a potent, noncompetitive EPAC1 inhibitor that blocks EPAC1-induced Rap1 activation both in cell-free systems and in intact cells and did not influence protein kinase A holoenzyme activity. |
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| DC23912 | Cecropin B | Cecropin B is an antimicrobial peptide with MICs(0.5 to 16 ug/ml) against Gramnegative strains. |
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| DC20987 | Cedazuridine Featured | Cedazuridine (E7727) is a novel cytidine deaminase inhibitor, and a componet of ASTX727 for treatment of hematologic malignancies.. |
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| DC3170 | Cediranib Featured | Cediranib (AZD2171) is a highly potent VEGFR2 inhibitor with IC50 of 0.5 nM, also inhibits Flt1/4 with IC50 of 5 nM/≤3 nM. |
|
| DCAPI1386 | Cefdinir (Omnicef) | Cefdinir (Omnicef) |
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