DCAPI1024 |
Cefditoren pivoxil |
Cefditoren pivoxil |
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DC8686 |
Cefetamet pivoxil hydrochloride |
Cefetamet pivoxil hydrochloride is an oral third generation cephalosporin antibiotic. |
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DC9358 |
Cefmenoxime (hydrochloride) |
Cefmenoxime hydrochloride is a third-generation cephalosporin antibiotic. |
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DCAPI1038 |
Cefoselis sulfate |
Cefoselis sulfate |
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DC20190 |
Cefoxitin |
Cefoxitin is a beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity. |
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DC8067 |
Cefozopran
Featured
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Cefozopran (SCE-2787) is a new parenteral cephalosporin, against experimental infections in mice. |
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DC9356 |
Cefpiramide (sodium) |
Cefpiramide sodium (SM-1652; Wy-44635) is a new Pseudomonas-active cephalosporin with a broad spectrum of antibacterial activity.
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DC8687 |
Cefpirome sulfate |
Cefpirome Sulfate is a fourth generation cephalosporin antibiotic. |
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DCAPI1033 |
Cefprozil hydrate (Cefzil) |
Cefprozil hydrate (Cefzil) |
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DC9355 |
Ceftibuten (dihydrate) |
Ceftibuten dihydrate is a third-generation cephalosporin antibiotic. |
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DC12245 |
Ceftizoxime |
Ceftizoxime is a bacterial inhibitor which acts by interfering with bacterial cell wall synthesis and inhibiting cross-linking of the peptidoglycan. |
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DCAPI1155 |
Celastrol
Featured
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Celastrol is a potent proteasome inhibitor for the chymotrypsin-like activity of a purified 20S proteasome with IC50 of 2.5 μM. |
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DCAPI1491 |
Celecoxib
Featured
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Celecoxib is a selective Cox-2 inhibitor (IC50 of 40 nM). Celecoxib shows low sensitivity against Cox-1 (IC50 of 15 μM). Celecoxib shows an anti-proliferative effect on nasopharyngeal carcinoma (NPC) cell lines including HNE1 (IC50of 32.86 μM) and CNE1-LM |
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DC7569 |
Z-LEHD-FMK |
Cell permeable fluoromethyl ketone (FMK)-derivatized peptides act as effective irreversible Caspase inhibitors with no cytotoxic effects and, therefore, are useful tools for studying Caspase activity. |
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DC7568 |
Z-DEVD-FMK
Featured
|
Cell-permeable, irreversible inhibitor of caspase-3/CPP32; inhibits tumor cell apoptosis. Neuroprotective in rat hippocampus following seizures in vivo. |
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DC9923 |
CeMMEC1
Featured
|
CeMMEC1 is a novel potent inhibitor of the second bromodomain of TAF1, binding neither the first nor the second bromodomain of BRD4. |
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DC23359 |
CeMMEC2 |
CeMMEC2 is a novel potent BRD4 inhibitor with IC50 of 0.9 uM, binds to both bromodomains of BRD4, comparably to (S)-JQ1.. |
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DC10357 |
Cenerimod |
Cenerimod (ACT-334441) is a potent and orally available sphingosine 1-phosphate 1 receptor (S1P1) agonist extracted from patent WO 2016184939 A1 and WO 2011007324 A1, example 1, with an EC50 of 2.7 nM. |
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DC10316 |
Cenicriviroc
Featured
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Cenicriviroc is an orally active, dual CCR2/CCR5 antagonist, and displays potent anti-inflammatory and aninfective activity. |
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DC21554 |
AS 703569 |
Cenisertib (AS 703569;R763) is a novel potent, orally available inhibitor of Aurora kinases, exhibits signifficant anti-proliferative activity against a wide range of tumor cells both in vitro and in vivo (A549 EC50=9 nM). |
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DC12318 |
Centanafadine hydrochloride (EB-1020 (hydrochloride)) |
Centanafadine (hydrochloride) is dual norepinephrine (NE)/dopamine (DA) transporter inhibitor, also inhibits serotonin transporter, with IC50s of 6 nM, 38 nM and 83 nM for human NE, DA and serotonin transporter , respectively. |
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DC12319 |
Centanafadine (EB-1020) |
Centanafadine is dual norepinephrine (NE)/dopamine (DA) transporter inhibitor, also inhibits serotonin transporter, with IC50s of 6 nM, 38 nM and 83 nM for human NE, DA and serotonin transporter , respectively. |
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DC10010 |
Centrinone
Featured
|
Centrinone is a selective and reversible inhibitor of polo-like kinase 4 (Plk4), a serine-threonine protein kinase that initiates centriole/centrosome assembly. |
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DC22796 |
CEP-1347 |
CEP-1347 (KT-7515) is a potent and selective MLK inhibitor that completely rescues motoneurons and inhibits JNK1 activation with IC50 of 20 nM. |
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DC8138 |
CEP-28122
Featured
|
CEP-28122 is a highly potent and selective orally active inhibitor of anaplastic lymphoma kinase with antitumor activity in experimental models of human cancers. |
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DC8777 |
CEP-32496 hydrochloride |
CEP-32496 Hcl is a highly potent inhibitor of BRAF(V600E/WT) and c-Raf with Kd of 14 nM/36 nM and 39 nM, also potent to Abl-1, c-Kit, Ret, PDGFRβ and VEGFR2, respectively; insignificant affinity for MEK-1, MEK-2, ERK-1 and ERK-2. |
|
DC8196 |
CEP-32496
Featured
|
CEP-32496 is a highly potent inhibitor of BRAF(V600E/WT) and c-Raf with Kd of 14 nM/36 nM and 39 nM, also potent to Abl-1, c-Kit, Ret, PDGFRβ and VEGFR2, respectively; insignificant affinity for MEK-1, MEK-2, ERK-1 and ERK-2. |
|
DC7099 |
CEP33779
Featured
|
CEP33779(< 3 μM) inhibits phosphorylation of downstream target signal transducer and activator of transcription 5(pSTAT5) of JAK2 in a concentration dependent manner in HEL92 cells. |
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DC8009 |
CEP-37440
Featured
|
CEP-37440 is a novel potent and selective Dual FAK/ALK inhibitor with IC50 s of 2.3 nM (FAK) and 120 nM(ALK cellular IC50 in 75% human plasma). |
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DC10337 |
CEP-40783
Featured
|
CEP-40783 is a potent, selective and orally available inhibitor of AXL and c-Met with IC50 values of 7 nM and 12 nM, respectively. |
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