DC7668 |
CL-387785
Featured
|
CL-387785(EKI785; WAY-EKI 785) is an irreversible inhibitor of EGFR with IC50 of 370+/-120 pM; is able to overcome resistance caused by the T790M mutation on a functional level. |
|
DC20910 |
CL-82198 hydrochloride |
CL-82198 is a potent, selective inhibitor of MMP-13 (89% inhibition at 10 ug/mL), displays no activity at MMP-1, MMP-9 and TACE, significantly reduces the migration of LS174 cells by 55% at 10 uM.. |
|
DC4205 |
Cladribine |
Cladribine (Leustatin, Litak, 2CDA) is an adenosine deaminase inhibitor for U266, RPMI8226, and MM1.S cells with IC50 of approximately 2.43 μM, 0.75 μM, and 0.18 μM, respectively. |
|
DC12292 |
Cl-amidine hydrochloride
Featured
|
Cl-amidine (hydrochloride) is a peptidylarginine deminase (PAD) inhibitor, with an IC50 5.9 μM for PAD4. |
|
DC9725 |
Cl-amidine
Featured
|
Cl-amidine is a cell-permeable compound that acts as a pan PAD inhibitor (IC50 = 0.8 µM, 6.2 µM and 5.9 µM for PAD1, PAD3, and PAD4, respectively) in enzymatic assays. |
|
DC9868 |
Clanfenur
Featured
|
Clanfenur is a substituted benzoylphenylurea and an analogue of the pesticide diflubenzuron with potential antineoplastic activity. |
|
DC8937 |
Clarithromycin |
Clarithromycin is a macrolide antibiotic and a CYP3A4 inhibitor. |
|
DC12407 |
Class I and IIB HDAC inhibitor 42 |
Class I and IIB HDAC inhibitor 42 is a novel potent, selective class I and IIB inhibitor (HDAC1 Ki=0.27 nM) for topical treatment of cutaneous t-cell lymphoma.. |
|
DC7387 |
Clemizole Hydrochloride
Featured
|
Clemizole is a H1 histamine receptor antagonist.Recently, researchers have identified that clemizole hydrochloride can inhibit NS4B's RNA binding and hepatitis C virus (HCV) replication. |
|
DC8832 |
Clemizole (free base)
Featured
|
Clemizole is a H1 histamine receptor antagonist.Recently, researchers have identified that clemizole hydrochloride can inhibit NS4B's RNA binding and hepatitis C virus (HCV) replication. |
|
DC9380 |
Cleviprex
Featured
|
Clevidipine(Clevidipine) is a short-acting dihydropyridine calcium channel antagonist (IC50= 7.1 nM, V(H) = -40 mV ) under development for treatment of perioperative hypertension.
|
|
DCAPI1085 |
Clevudine (Levovir)
Featured
|
Clevudine (Levovir) is an antiviral drug for the treatment of hepatitis B,showed potent activity against COVID-19(SARS-COV-2) . |
|
DCAPI1113 |
Clindamycin HCl (Dalacin) |
Clindamycin HCl (Dalacin) |
|
DCAPI1131 |
Clindamycin phosphate |
Clindamycin phosphate |
|
DC10204 |
Clinofibrate |
Clinofibrate (S-8527) is a hypelipidemic agent and a HMG-CoA reductase inhibitor. |
|
DC10242 |
5-Chloro-8-hydroxy-7-iodoquinoline |
Clioquinol is an orally bioavailable, lipophilic, copper-binding, halogenated 8-hydroxyquinoline with antifungal, antiparasitic and potential antitumor activities. |
|
DC21722 |
CLK-IN-T3
Featured
|
CLK inhibitor T3 (T3) is a highly potent, selective, and cell-based stable CDC-like kinase (CLK) inhibitor with 0.67, 15 and 110 nM for CLK1,2 and 3, respectively. |
|
DC11004 |
CLK2 inhibitor Indazole1 |
CLK2 inhibitor Indazole1 is a novel potent, selective inhibitor of CLK2 with IC50 of 2.7 nM, 60-fold selectivity over PKA and >600-fold selectivity over a panel of 34 kinases. |
|
DC23464 |
Clobenpropit |
Clobenpropit (VUF-9153) is a highly potent histamine H3 antagonist/inverse agonist with pA2 value of 9.93, also displays partial agonist activity at H4 receptors. |
|
DC23440 |
Clobenpropit dihydrobromide |
Clobenpropit (VUF-9153) is a highly potent histamine H3 antagonist/inverse agonist with pA2 value of 9.93, also displays partial agonist activity at H4 receptors. |
|
DCAPI1133 |
Clobetasol propionate |
Clobetasol propionate |
|
DC12304 |
Clocapramine hydrochloride hydrate (3-Chlorocarpipramine hydrochloride hydrate) |
Clocapramine hydrochloride hydrate is an antagonist of the D2 and 5-HT2A receptors. |
|
DCAPI1428 |
Clofarabine
Featured
|
Clofarabine(Clolar; Clofarex) inhibits the enzymatic activities of ribonucleotide reductase (IC50 = 65 nM) and DNA polymerase. IC50 Value: 65 nM Target: in vitro: Clofarabine is a second generation purine nucleoside analog with antineoplastic activity. It |
|
DC9156 |
Clofazimine |
Clofazimine is a fat-soluble iminophenazine dye, has a marked anti-inflammatory effect, has been used in combination with other antimycobacterial drugs to treat AIDS and Crohn's disease. |
|
DC8681 |
Clofentezine |
Clofentezine, a growth inhibitor, has sublethal effects on life-table parameters of Tetranychus urticae Koch females. |
|
DC9183 |
Clomiphene citrate |
Clomifene Citrate is a selective estrogen receptor modulator. |
|
DC9081 |
Clomipramine HCL |
Clomipramine HCl is a serotonin transporter (SERT), norepinephrine transporter (NET) dopamine transporter (DAT) blocker with Ki of 0.14, 54 and 3 nM, respectively. |
|
DC9021 |
Clonidine hydrochloride |
Clonidine Hydrochloride is a centrally acting alpha-agonist hypotensive agent. |
|
DC3147 |
Clopidogrel hydrogensulfate |
Clopidogrel (Plavix) is an oral, thienopyridine class antiplatelet agent. |
|
DCAPI1417 |
Clopidogrel |
Clopidogrel is an irreversible inhibitor of the P2Y12 receptor, which is responsible for initiating signal transduction via a GPCR. The signal cascade initiates platelet aggregation and thus clopidogrel has the effect of “thinning” the blood. |
|