| DC9129 |
Gabexate mesylate |
Gabexate Mesylate is a Factor X inhibitor. |
|
| DCAPI1037 |
Gadodiamide (Omniscan)
Featured
|
Gadodiamide is a gadolinium-based contrast agent used in MR imaging procedures to assist in the visualization of blood vessels. Target: OthersGadodiamide(Omniscan) is a gadolinium-based contrast agent used in MR imaging procedures to assist in the visualization of blood vessels. Gadodiamide is a contrast medium for cranial and spinal magnetic resonance imaging (MRI) and for general MRI of the body after intravenous administration. The product provides contrast enhancement and facilitates visualisation of abnormal structures or lesions in various parts of the body including the central nervous system (CNS). A recent review takes the question of toxicity caused by loss of gadolinium from the complex. "The challenge for nephrologists includes (a) evidence of transmetallation, such as gadolinium deposits in bone, increased urinary zinc excretion, iron-transferrin dissociation or 'spurious hypocalcemia' in exposed people"。 |
|
| DC11053 |
GAK inhibitor 49
Featured
|
GAK inhibitor 49 is a potent, selective, ATP-competitive inhibitor of cyclin G-associated kinase (GAK, cell IC50=56 nM) with favourable NAK family selectivity (AAK1, STK16, BMP2K). |
|
| DC9859 |
GAL-021
Featured
|
GAL-021 is a new intravenous BKCa-channel blocker. |
|
| DC12228 |
Galactose 1-phosphate |
Galactose 1-phosphate is an intermediate in the galactose metabolism and nucleotide sugars. |
|
| DC12305 |
Galactose 1-phosphate Potassium salt |
Galactose 1-phosphate Potassium salt is is an intermediate in the galactose metabolism and nucleotide sugars |
|
| DC7861 |
(-)-Narwedine
Featured
|
Galantamine(Narwedin) is a competitive and reversible cholinesterase(AChE) inhibitor. |
|
| DC9090 |
Galanthamine hydrobromide |
Galanthamine hydrobromide is a long-acting, centrally active acetylcholinesterase(AChE) inhibitor (IC50 = 410 nM) and allosteric potentiator at neuronal nicotinic ACh receptors. |
|
| DC21038 |
Galvestine-1 |
Galvestine-1 is a small molecule MGDG (monogalactosyldiacylglycerol) synthase inhibitor with IC50 of 10 uM by competing with diacylglycerol binding. |
|
| DC11071 |
Gambogenic acid |
Gambogenic acid (GNA) is a polyprenylated xanthone isolated from gamboge, shows potent antitumor activity and can effectively inhibit the survival and proliferation of cancer cells. |
|
| DC10133 |
Gambogic Acid
Featured
|
Gambogic Acid activates caspases with EC50 of 0.78-1.64 μM and competitively inhibits Bcl-xl, Bcl-2, Bcl-w, Bcl-B, Bfl-1 and Mcl-1 with IC50 of 1.47 μM, 1.21 μM, 2.02 μM, 0.66 μM, 1.06 μM and 0.79 μM, respectively. |
|
| DC12090 |
Gamitrinib TPP |
Gamitrinib TPP is a GA mitochondrial matrix inhibitor. |
|
| DC9640 |
gamma-secretase modulator 3 |
gamma-secretase modulator 3 is a gamma-secretase modulator. |
|
| DC21197 |
Ganaplacide
Featured
|
Ganaplacide (KAF156, GNF-156) is a novel antimalarial clinical candidate that shows blood schizonticidal activity with IC50 of 6-17.4 nM against P falciparum drug-sensitive and drug-resistant strains. |
|
| DCAPI1357 |
Ganciclovir |
Ganciclovir |
|
| DC7320 |
Ganetespib(STA-9090)
Featured
|
Ganetespib(STA-9090) is a unique triazolone-containing Hsp90 inhibitor with an IC50 of 4 nM in OSA 8 cells. |
|
| DC8877 |
Ganirelix
Featured
|
Ganirelix is a man-made form of a protein that reduces the amount of certain hormones in the body, including estrogen. |
|
| DC9453 |
GANT 58 |
GANT 58 is a novel and potent Gli antagonist that inhibits GLI1-induced transcription (IC50 = 5 uM). |
|
| DC7129 |
GANT61(NSC 136476)
Featured
|
GANT 61(NSC 136476) is a small molecule inhibitor of Gli1 and Gli2. |
|
| DC20388 |
GAPDS
Featured
|
GAPDS is a small molecule that targets the glycolytic enzyme glyceraldehyde 3-phosphate dehydrogenase (GAPDH). |
|
| DC23398 |
Garcinol |
Garcinol (Camboginol) is a potent, natural inhibitor of histone acetyltransferases (HATs) p300 (IC50=7 uM) and PCAF (IC50=5 uM) both in vitro and in vivo. |
|
| DC26031 |
Gardiquimod trifluoroacetate
Featured
|
Gardiquimod trifluoroacetate is a specific TLR7 agonist which can also inhibit HIV-1 reverse transcriptase. |
|
| DC8929 |
Garenoxacin |
Garenoxacin is a quinolone antibiotic for the treatment of Gram-positive and Gram-negative bacterial infections. |
|
| DC8893 |
Garenoxacin Mesylate hydrate |
Garenoxacin mesylate hydrate is a novel oral des-fluoro(6) quinolone with potent antimicrobial activity, against common respiratory pathogens, including resistant strains. |
|
| DC11122 |
GAT-100 |
GAT-100 (GAT100) is a potent, selective CB1R negative allosteric modulator (NAM) with cAMP EC50 and β-arr EC50 of 174 nM and 2.1 nM, does not exhibit inverse agonism. |
|
| DC11119 |
GAT-211 |
GAT-211 (GAT211) is a selective cannabinoid 1 receptor (CB1R) positive allosteric modulator with pKb of 7.26, Arrestin2 EC50 of 775 nM. |
|
| DC11741 |
GB-110 |
GB-110 is a potent, non-peptidic agonist of PAR2 that selectively induces PAR2-mediated intracellular Ca(2+) release in HT29 cells with EC50 of 0.28 uM. |
|
| DC22098 |
GB1107 |
GB1107 (GB-1107, GB 1107) is a potent, selective, orally active inhibitor of Galectin-3 (Gal-3) with Kd of 37 nM (human Galectin-3). |
|
| DC21040 |
GB-83 |
GB-83 is a selective, reversible PAR2 (Protease-activated receptor 2) antagonist with IC50 of 2 uM. |
|
| DC11740 |
GB-88 |
GB-88 is a selective, orally available PAR2 antagonist that inhibits PAR2 activated Ca(2+) release with IC50 of 2 uM. |
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