| DC22531 |
Naquotinib |
Naquotinib (ASP-8273) is a potent, irreversible, mutant-selective inhibitor of EGFR (IC50=8-33 nM for (L858R, exon 19 deletion, L858R/T790M, and del19/T790M)). |
|
| DC22526 |
Naquotinib mesylate |
Naquotinib (ASP-8273) is a potent, irreversible, mutant-selective inhibitor of EGFR (IC50=8-33 nM for (L858R, exon 19 deletion, L858R/T790M, and del19/T790M)). |
|
| DCAPI1460 |
Naratriptan hydrochloride |
Naratriptan Hydrochloride is a triptan drug which is used for the treatment of migraine headaches. |
|
| DC20700 |
Naronapride |
Naronapride (ATI-7505) is a potent, selective and orally active 5-HT4 receptor agonist with Ki of 1.4 nM. |
|
| DC21361 |
N-aryl benzimidazole |
N-aryl benzimidazole (NAB) is a small molecule that strongly and selectively protects diverse cell types from α-syn toxicity, promotes endosomal transport events dependent on the E3 ubiquitin ligase Rsp5/Nedd4 in wild-type yeast cells.. |
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| DC23157 |
Naspm trihydrochloride
Featured
|
Naspm is a selective antagonist of Ca2+-permeable AMPA receptors, blocks GluR2-lacking AMPARs, suppresses current responses induced by kainate in type II neurons with IC50 of 0.33 uM. |
|
| DC9341 |
Naspm
Featured
|
Naspm(1-Naphthylacetyl spermine) is a potent and selective Ca2+ permeable AMPA receptor(Ca-perm AMPAR) blocker.
IC50 value:
Target: CP-AMPAR blocker
Naspm is a selective blocker of Ca(2+)-permeable GluA2-lacking AMPA receptors, reduced MNNG-induced CA1 |
|
| DCAPI1337 |
Natamycin(Pimaricin) |
Natamycin(Pimaricin) |
|
| DC9063 |
Nateglinide |
Nateglinide is an insulin secretagog agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). |
|
| DCAPI1056 |
Nattokinase
Featured
|
Nattokinase, Natto fermentation is a potent fibrinolytic enzyme. Nattokinase can break down blood clots by directly hydrolyzing fibrin and plasmin substrate. Nattokinase can be used for the research of cardiovascular diseases. |
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|
| DC26021 |
6,8(2H,7H)-Isoquinolinedione,7-(acetyloxy)-5-chloro-3-(3,5-dimethyl-1,3-heptadienyl)-7-methyl- (9CI)
Featured
|
Natural product derived from fungal source. |
|
| DC8666 |
Nav1.7-IN-2 |
Nav1.7-IN-2 is an inhibitor of voltage-gated sodium channels (Nav), in particular Nav 1.7, with IC50 of 80 nM. |
|
| DC20025 |
Nav1.7-IN-3 |
Nav1.7-IN-3 is a selective, orally bioavailable voltage-gated sodium channel Nav1.7 inhibitor with an IC50 of 8 nM. Pain relief. Limited CNS penetration. |
|
| DC11971 |
NAV-2729（Grassofermata）
Featured
|
NAV 2729 (NAV2729) is a chemical potentiator for mRNA-LNPs, increasing the delivery efficiencies of mRNA-LNPs in vitro and in vivo. |
|
| DC20472 |
Naxillin
Featured
|
Naxillin is the first non-auxin-like molecule that promotes root branching, activates a subset of auxin-induced transcripts, including AUX/IAA, SAUR and PIN families; induces auxin response in the basal meristem; represents a valuable tool to further decipher the molecular networks involved in lateral root branching. |
|
| DC9790 |
Nazartinib(EGF816)
Featured
|
Nazartinib(EGF816) is a novel covalent inhibitor of mutant-selective EGFR; overcomes T790M-mediated resistance in NSCLC. |
|
| DC21362 |
NBC19 |
NBC19 is a potent inhibitor of NLRP3 inflammasome, inhibits nigericin-induced ASC speck formation in post-differentiated THP1 cells with IC50 of 60 nM.. |
|
| DC9476 |
NBD-556
Featured
|
NBD-556 is small molecule mimetic of CD4, NBD-556 recognizes the HIV-1 envelope protein gp120 and induces restructuring of gp120 analogous to CD4 binding.
|
|
| DC9477 |
NBD-557 |
NBD-557 is a potentially HIV-1 inhibitor.
|
|
| DC7209 |
NBI42902 |
NBI-42902 is a potent inhibitor of peptide radioligand binding to the human GnRH receptor (K(i) = 0.56 nm). |
|
| DC23638 |
NBQX disodium |
NBQX disodium is the water soluble disodium salt of NBQX, which is a potent, selective and competitive AMPA receptor (AMPAR) antagonist with IC50 of 0.15 uM. |
|
| DC11406 |
NBQX
Featured
|
NBQX is a potent aminomethylphosphonic acid receptor (AMPAR) antagonist with an IC50 of 0.7 ± 0.1 μM. |
|
| DC21364 |
NC-001
Featured
|
NC-001 (NC 001, NC001, az-NC-001) is a potent, specific, cell-permeable inhibitor of immunoproteasome caspase-like sites (β1i and β1), does not correlate with inhibition of chymotrypsin-like sites.. |
|
| DC21366 |
NC-043 |
NC-043 (15-Oxospiramilactone) is a diterpenoid derivative inhibitor of Wnt/β-catenin signaling that interferes with the β-catenin/TCF4 association. |
|
| DC9770 |
NCB-0846
Featured
|
NCB-0846 is a novel,first-in-class,orally TNIK inhibitor with an IC50 value of 21 nM,that have shown strong anti-tumor efficacy against several cancer models. |
|
| DC22316 |
NCC007
Featured
|
NCC007 is a novel CKIα and CKIδ dual inhibitor. NCC007 that showed stronger period effects (0.32 μM for 5 h period lengthening) in a cellbased circadian assay. |
|
| DC23377 |
NCD-25 |
NCD-25 is a novel potent, selective LSD1 inhibitor with IC50 of 0.48 uM, exerts highly selective inhibitory activity on LSD1 but no other enzymes, such as MAO.. |
|
| DC23353 |
NCD-38 |
NCD-38 is a novel potent, selective LSD1 inhibitor with IC50 of 0.59 uM, exerts highly selective inhibitory
activity on LSD1 but no other enzymes, such as MAO (IC50>100 uM). |
|
| DC21369 |
NCGC 00067819
Featured
|
NCGC 00067819 is a small molecule compound that potentiates CREB signaling with EC50 of 16 nM in the primary screen and 79 nM in the CHO CRE-β-lactamase confirmation assay. |
|
| DC23699 |
NCGC00071837 |
NCGC00071837 (PDE4-IN-5A) is a potent, selective PDE4 inhibitor with IC50 of 24 and 18 nM for PDE4A and PDE4D, respectively, weak inhibition for PDE4B (IC50=0.54 uM) and inactive for PDE1/3/5/7/9/10/11. |
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