| DCAPI1513 |
Nefopan hydrochloride |
Nefopanhydrochloride |
|
| DC8194 |
PP3
Featured
|
Negative control for the Src kinase inhibitor PP2. |
|
| DC8290 |
(S)-PFI-2 HCl
Featured
|
Negative control of (R)-PFI 2 hydrochloride. Exhibits 500-fold lower activity in a SETD7 enzymatic assay (IC50 = 1 μM) compared to the active enantiomer. |
|
| DC8823 |
XY1
Featured
|
Negative control of SGC 707. Exhibits >3000-fold lower potency (IC50 >100 μM) compared to the active analog. |
|
| DC12465 |
NEK6 inhibitor 8
Featured
|
NEK6 inhibitor 8(ZINC05007751) is a novel inhibitor of the NIMA-related kinase NEK6 with IC50 of 3.4 uM, compound 8 is very selective against NEK1 and NEK6, while no signifcant activity was observed against NEK2, NEK7, and NEK9. |
|
| DC20743 |
Neladenoson dalanate |
Neladenoson dalanate is a potent, selective, orally acitve partial adenosine A1 receptor (A1AR) agonist (EC50=0.1 nM) for the treatment of chronic heart failure.. |
|
| DC20744 |
Neladenoson dalanate hydrochloride |
Neladenoson dalanate is a potent, selective, orally acitve partial adenosine A1 receptor (A1AR) agonist (EC50=0.1 nM) for the treatment of chronic heart failure.. |
|
| DC4129 |
Arranon
Featured
|
Nelarabine (Arranon, 506U78) is a purine nucleoside analog and DNA synthesis inhibitor with IC50 from 0.067-2.15 μM in tumor cells. |
|
| DC10355 |
Nelfinavir
Featured
|
Nelfinavir(AG-1341) is a potent and orally bioavailable human immunodeficiency virus HIV-1 protease inhibitor (Ki=2 nM) and is widely prescribed in combination with HIV reverse transcriptase inhibitors for the treatment of HIV infection. |
|
| DC9474 |
Nelfinavir (Mesylate) |
Nelfinavir(AG-1341) is a potent and orally bioavailable human immunodeficiency virus HIV-1 protease inhibitor (Ki=2 nM) and is widely prescribed in combination with HIV reverse transcriptase inhibitors for the treatment of HIV infection. |
|
| DC11247 |
Nelonicline
Featured
|
Nelonicline (ABT-126) is a potent, selective α7 nicotinic receptor (nAChR) partial agonist for the treatment of cognitive impairment with schizophrenia.. |
|
| DC11469 |
APD125(Nelotanserin)
Featured
|
Nelotanserin is a potent 5-HT2A inverse agonist, a moderately potent 5-HT2C partial inverse agonist and a weak 5-HT2B inverse agonist, with IC50s of 1.7, 79, 791 nM in IP accumulation assays, respectively. |
|
| DC22175 |
NEO214 |
NEO214 (NEO-214) is a novel, BBB-permeable rolipram-perillyl alcohol conjugate, shows effectivity against both TMZ-sensitive and TMZ-resistant glioma cells (T98G IC50=40 uM). |
|
| DC23087 |
Neoandrographolide
Featured
|
Neoandrographolide has antiradical, anti-inflammatory,and hypolipidemic effects, it protects the cardiovascular without significant liver damage. Neoandrographolide as chemosensitizer in S-Jurkat and X chromosome-linked inhibitor of apoptosis protein (XIA |
|
| DC9046 |
Neostigmine bromide |
Neostigmine Bromide is a cholinesterase inhibitor used in the treatment of myasthenia gravis. |
|
| DCAPI1543 |
Neostigmine Methylsulfate |
Neostigmine Methyl Sulfate is a reversible acetylcholinesterase inhibitor. This compound blocks the breakdown of acetylcholine in the synaptic space, leading to prolonged signaling and thus increased muscle contractions. |
|
| DCAPI1342 |
Nepafenac |
Nepafenac |
|
| DC5177 |
Nepicastat HCl (SYN-117)
Featured
|
Nepicastat hydrochloride is a potent and selective inhibitor of both bovine and human dopamine-β-hydroxylase with IC50 of 8.5 nM and 9 nM, with negligible affinity for twelve other enzymes and thirteen neurotransmitter receptors. |
|
| DC7211 |
Neratinib (HKI-272)
Featured
|
Neratinib (HKI-272) is an orally available, irreversible tyrosine kinase inhibitor with IC50 of 59 nM and 92 nM for HER2 and EGFR, respectively. |
|
| DC23057 |
Nestorone |
Nestoron2 (ST1435, Elcometrine) is a 19-norprogesterone derivative and steroidal progestin which is used as a hormonal contraceptive, a high-affinity agonist of the progesterone receptor.. |
|
| DC22636 |
Netarsudil dihydrochloride
Featured
|
Netarsudil (AR-13324) is a potent, selective ROCK inhibitor with Ki of 4.2 nM for ROCK2. |
|
| DC11550 |
Netazepide |
Netazepide (YF476, Sograzepide) is a potent, selective and orally active gastrin/CCK-2 antagonist with IC50 of 0.1 nM. |
|
| DC9353 |
Netilmicin (sulfate) |
Netilmicin Sulfate is an active aminoglycoside antibiotic against most Gram-negative and some Gram-positive bacteria, including certain strains resistant to gentamicin. |
|
| DC8100 |
Netupitant |
Netupitant is a highly potent and selective, orally active neurokinin-1 receptor antagonist with Ki of 0.95 nM. |
|
| DC23275 |
NEU-1953(NEU1953) |
NEU-1953 (NEU1953) is a potent inhibitor of P. falciparum with EC50 of 0.43 uM (T. brucei), demonstrates improved ADME profile over the NEU-961.. |
|
| DC5131 |
Neuropathiazol
Featured
|
Neuropathiazol selectively induces neuronal differentiation of primary hippocampal neural progenitor cells. It is more potent and selective compared to retinoic acid. Also suppresses astrocyte differentiation. |
|
| DC12238 |
Neurotoxin Inhibitor |
Neurotoxin Inhibitor is a neurotoxin inhibitor. |
|
| DC9019 |
Nevirapine |
Nevirapine is a potent, non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with nucleoside analogues for treatment of HIV-1 infection and AIDS. |
|
| DC23016 |
Nexinhib 20 |
Nexinhib 20 is a novel small molecule neutrophil exocytosis inhibitor (IC50=0.33 uM) that specifically inhibits Rab27a-JFC1 binding (IC50=2.6 uM) but does not interfere with the interaction of other Rab GTPases and effectors. |
|
| DC7548 |
Nexturastat A
Featured
|
Nexturastat A is a potent and selective HDAC6 inhibitor with IC50 of 5 nM, >190-fold selectivity over other HDACs. |
|
