DC7588 |
PNU120596
Featured
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PNU-120596 is a positive allosteric modulator of α7 nAChR with EC50 of 216 nM. |
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DC7648 |
PNU159682
Featured
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PNU-159682 is a major bioactive metabolite of Nemorubicin in human liver microsomes; > 3,000-fold cytotoxic than its parent compound(MMDX and doxorubicin). |
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DC10409 |
PNU-74654 |
PNU-74654 is an inhibitor of Wnt/β-catenin pathway with an IC50 of 129.8 μM in NCI-H295 cell. |
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DC10760 |
Pocapavir
Featured
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Pocapavir is an investigational enterovirus (EV) capsid inhibitor. |
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DC6504 |
Patchouli Alcohol
Featured
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Pogostemon (patchouli) leaves and their extracted oils are used in perfumes and in traditional medicine to relieve sunstroke, stop vomiting, and increase appetite. |
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DC11373 |
Polmacoxib |
Polmacoxib is an inhibitor of cyclooxygenase 2 (COX-2) and the carbonic anhydrase subtypes I (CAI) and CAII. |
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DC26094 |
Poloppin II |
Poloppin II is an orally active, Poloppin derivative inhibitor of protein-protein interaction via the PBD of the mitotic Polo-like kinase (PLK) with IC50 of 41 uM in FP assays, exhibits IC50 of 61 nM cellular assay for mitotic arrest. |
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DC26116 |
Poloppin
Featured
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Poloppin is a cell-active, small molecule inhibitor of protein-protein interaction via the Polo-box domain (PBD) of the mitotic Polo-like kinase (PLK) with IC50 of 26.9 uM (PLK1) in FP assays. |
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DC9594 |
Poloxin
Featured
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Poloxin is a non-ATP competitive Polo-like Kinase 1 (PLK1) inhibitor that targets the polo-box domain. |
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DCAPI1298 |
Polydatin(Piceid) |
Polydatin(Piceid) |
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DC10214 |
Polymyxin B sulphate
Featured
|
Polymyxin B is an antibiotic primarily used for resistant gram-negative infections. |
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DC22413 |
Pomaglumetad Methionil |
Pomaglumetad Methionil (LY2140023 monohydrate) is the methionine amide prodrug of the mGluR2/3 agonist LY-404039 with the potential oral treatment of schizophrenia.. |
|
DC26122 |
Pomalidomide-C2-NH2 hydrochloride |
Pomalidomide-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology. |
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DC26126 |
Cereblon Ligand-Linker Conjugates 9(E3 Ligase Ligand-Linker Conjugates 2)
Featured
|
Pomalidomide-PEG4-Ph-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 4-unit PEG linker used in PROTAC technology. |
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DC9742 |
Ponesimod
Featured
|
Ponesimod(ACT-128800) is an orally active, selective sphingosine-1-phosphate receptor 1 (S1P1) immunomodulator with EC50 of 5.7 nM. |
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DC10829 |
Porcupine-IN-1
Featured
|
Porcupine-IN-1 is potent porcupine inhibitor with an IC50 of 0.5±0.2 nM. |
|
DCAPI1093 |
Posaconazole
Featured
|
Posaconazole (Noxafil) is a sterol C14ɑ demethylase inhibitor with an IC50 of 0.25 nM. |
|
DC11914 |
Poseltinib
Featured
|
Poseltinib (HM-71224, LY-3337641) is a potent and selective, covalent inhibitor of Btk with IC50 of 1.95 nM. |
|
DCAPI1336 |
Potassium iodide |
Potassium iodide |
|
DC20217 |
Potassium thioacetate |
Potassium thioacetate is widely used as a sulfur source in the synthesis of sulfur-containing organic compounds. It has been employed for the synthesis of heterocycles, polymers, transition-metal ligands, nanoparticles, bioactive compounds and macromolecu |
|
DC7492 |
SB 258585 hydrochloride |
Potent and selective 5-HT6 receptor antagonist (pKi = 8.6). |
|
DC9213 |
GBR12783 |
Potent and selective DA uptake inhibitor |
|
DC8022 |
R-268712
Featured
|
Potent and selective inhibitor of the TGF-β type I receptor/ALK5 (IC50 = 2.5 nM). Exhibits ~ 5000-fold selectivity over p38 MAPK. Suppresses development of renal fibrosis in a unilateral ureteral obstruction model. Also reduces proteinuria, glomeruloscler |
|
DC8603 |
SR 49059
Featured
|
Potent and selective non-peptide vasopressin V1A receptor antagonist; devoid of agonist activity. Displays high affinity and efficacy at both rat (KI=1.6 nM) and human (KI -1.1 - 6.3 nM) V1A receptors. |
|
DC8590 |
CRT-0066101 hydrochloride
Featured
|
Potent inhibitor of protein kinase D (PKD); inhibits all PKD isoforms (IC50 values are 1, 2 and 2.5 nM for PKD1, PKD3 and PKD2 respectively). |
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DC7574 |
FIPI
Featured
|
Potent phosholipase D (PLD) inhibitor (IC50 values are 20 and 25 nM for PLD2 and PLD1 respectively). |
|
DC8604 |
Pim-1 Inhibitor 2 |
PIM1-IN-2 is a highly effective and ATP-competitive inhibitor of Pim-1, demonstrating a Ki value of 91 nM. Unlike traditional inhibitors, it interacts with the ATP-binding kinase hinge region without relying on the formation of standard hydrogen bonds, showcasing a unique mechanism of action. This distinctive approach highlights its potential as a promising therapeutic agent. |
|
DC23003 |
hypocrellin A
Featured
|
Potent PKC inhibitor. Photosensitizing agent. Potent antileishmanial agent. |
|
DC7370 |
AZ-628
Featured
|
Potent, ATP-competitive inhibitor of Raf kinases (IC50 values are 29, 34 and 105 nM For c-Raf1, B-RafV600E and wild-type B-Raf, respectively). Displays selectivity For Raf kinases over a panel of 150 other kinases. |
|
DC8484 |
KN-93(free base)
Featured
|
Potent, cell permeable inhibitor of CaM kinase II (IC50 = 0.37 μM). |
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