DC9987 |
RAF709
Featured
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RAF709 is a novel Raf kinase inhibitor extracted from patent WO2014151616A1, compound example 131, has an IC50 of 0.5 and 1.8 nM for c-Raf and b-Raf, respectively. |
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DC8930 |
Rafoxanide |
Rafoxanide is a salicylanilide used as an antiparasitic agent. |
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DC10899 |
Ralinepag
Featured
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Ralinepag is a potent, orally bioavailable and non-prostanoid prostacyclin (IP) receptor agonist, with EC50s of 8.5 nM, 530 nM and 850 nM for human and rat IP receptor and human DP1 receptor, respectively. |
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DCAPI1577 |
Raloxifene |
Raloxifene hydrochloride is a selective estrogen receptor modulator (SERM), binding to ERα and ERβ. Tissue-dependently blocks or activates estrogen-induced transcription. Exhibits estrogen agonist behavior in bone but acts as an anti-estrogen in breast an |
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DC9166 |
Raloxifene HCl |
RaloxifeneHcl(LY156758 Hcl) is a second generation selective estrogen receptor antagonist. |
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DC9479 |
Raltegravir (potassium salt) |
Raltegravir potassium salt(MK0518 potassium salt) is a potent integrase (IN) inhibitor, used to treat HIV infection.
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DCAPI1581 |
Raltegravir
Featured
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Raltegravir Salt is a potent human immunodeficiency virus (HIV) integrase inhibitor and a novel anti-AIDS drug. |
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DC8940 |
Raltitrexed
Featured
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Raltitrexed(ZD1694), an inhibitor of thymidylate synthase, is an antimetabolite drug used in cancer chemotherapy. |
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DC6918 |
Ramatroban (BAY u3405) |
Ramatroban (BAY u3405) is a thromboxane A(2) (TxA(2)) antagonist marketed for allergic rhinitis. |
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DC7828 |
Ramelteon |
Ramelteon is a novel melatonin receptor agonist for human MT1 and MT2 receptors and chick forebrain melatonin receptors with Ki of 14 pM, 112 pM and 23.1 pM, respectively. |
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DC9128 |
Ramipril |
Ramipril is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 5 nM. |
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DC9322 |
Ramosetron (Hydrochloride)
Featured
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Ramosetron Hydrochloride(YM060 Hydrochloride) is a serotonin 5-HT3 receptor antagonist for the treatment of nausea and vomiting.
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DCAPI1391 |
Ranolazine (Ranexa)
Featured
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Ranolazine (Ranexa) |
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DC9162 |
Ranolazine HCl
Featured
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Ranolazine(RS-43285) is an antianginal agent with antiarrhythmic properties that achieves its effects via a novel mechanism of action (inhibition of the late phase of the inward sodium current), without affecting heart rate or blood pressure (BP). |
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DC11816 |
RapaLink-1
Featured
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RapaLink-1 is a third-generation mTOR inhibitor that overcomes resistance to existing first- and second-generation inhibitors; blocks mTOR signaling of the F2108L mTOR and M2327I mTOR drug resistant mutants; RapaLink-1 is more potent mTOR inhibitor than rapamycin. |
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DC1048 |
Rapamycin (Sirolimus)
Featured
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Rapamycin (Sirolimus, AY-22989, WY-090217) is a specific mTOR inhibitor with IC50 of ~0.1 nM. - |
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DC8175 |
Rapastinel(GLYX-13)
Featured
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Rapastinel(GLYX-13) is a NMDA receptor partial agonist that acts at the glycine site. |
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DC10878 |
Raphin1
Featured
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Raphin1 is an orally available selective phosphatase inhibitor improves proteostasis and
diminishes deficits in a mouse model of Huntington’s disease. |
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DC12624 |
RAS activator compound 1
Featured
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RAS activator compound 1 is a small molecule RAS activator compound that increases the rate of SOS-catalyzed nucleotide exchange in vitro with EC50 of 14 uM; targets SOS1 induced biphasic modulation of RAS-GTP and ERK phosphorylation levels, through negative feedback on SOS1 that regulates the interaction between SOS1 and GRB2. |
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DC11216 |
RAS inhibitor Abd-7 |
RAS inhibitor Abd-7 is a potent RAS-binding compound (Kd=51 nM) that interacts with RAS in cells, prevents RAS-effector interactions and inhibits endogenous RAS-dependent signalling. |
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DCAPI1486 |
Rasagiline Mesylate |
Rasagiline Mesylate is an antiparkinsonian and a selective irreversible MAO-B inhibitor. |
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DC10949 |
RasGRP3 ligand 96
Featured
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RasGRP3 ligand 96 is a potent, selective ligand of Ras guanine-releasing protein 3 (RasGRP3) with Ki of 1.75 nM, showed 73-fold and 45-fold selectivity relative to PKCα and PKCε for in vitro binding activity resepctively. |
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DC21526 |
Ravidasvir free base
Featured
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Ravidasvir (PPI-668;BI 238630) is a potent pan-genotypic HCV NS5A inhibitor with IC50 of 0.12/0.01/1.14 nM for HCV gt-1a/1b/3a in replicon luciferase assay; |
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DC8190 |
Ravidasvir hydrochloride (PPI-668)
Featured
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Ravidasvir(PPI-668) is a NS5A Inhibitor. |
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DC11528 |
Razuprotafib
Featured
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Razuprotafib is a potent protein tyrosine phosphatase β (HPTPβ) inhibitor.. |
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DC11549 |
Razuprotafib sodium |
Razuprotafib sodium is a potent protein tyrosine phosphatase β(HPTPβ) inhibitor.. |
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DC11161 |
RB-005 |
RB-005 (RB-005) is a potent, selective inhibitor of sphingosine kinase SphK1 (SK1) with IC50 of 3.6 uM, displays 15-fold selectivity over SphK2.. |
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DC21558 |
RB-101 |
RB-101 is an mixed enkephalinase inhibitor that inhibits Aminopeptidase N and Neutral Endopeptidase with IC50 of 11 nM and 2 nM, respectively. |
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DC11430 |
RB-394 |
RB394 is an orally bioavailable and dual modulator of soluble epoxide hydrolase (sEH) and PPARγ. |
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DC8143 |
RBC8
Featured
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RBC8 is a novel small molecule inhibitor of Ral GTPase; has IC50 of 3.5 μM in H2122 cell and 3.4 μM in H358 cell. |
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