GYKI 52466 dihydrochloride

  Cat. No.:  DC5061  
Chemical Structure
102771-26-6
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Field of application
GYKI 52466 dihydrochloride is a selective non-competitive AMPA receptor antagonist (IC50 values are 10-20, ~ 450 and >> 50 μM for AMPA- , kainate- and NMDA-induced responses respectively). Skeletal muscle relaxant and orally-active anticonvulsant.
Cas No.: 102771-26-6
Chemical Name: 4-(8-Methyl-9H-1,3-dioxolo4,5-h2,3benzodiazepin-5-yl)benzenamine
Synonyms: Benzenamine,4-(8-methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)-;4-(8-Methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)benzenamine;4-(8-methyl-9H-[1,3]dioxolo[4,5-h][2,3]benzodiazepin-5-yl)aniline;GYKI 52466 dihydrochloride;GYKI 52466 HYDROCHLORIDE;GYKI-52466;1-(4-aminophenyl)-4-methyl-7,8-methylenedioxy-5H-2,3-benzodiazepine;1-(n-hexadecyloxy);2,3;4-(8-methoxy-3,6-dioxa-1-undecoxy) benzene;4-(8-methyl-9H-1,3-dioxa-6,7-diaza-cyclohepta[f]inden-5-yl)-phenylamine;4,5-h;8-methyl-5-(4-aminophenyl)-9H-1,3-dioxolo;Benzene, 1-(hexadecyloxy)-4-[2-(2-methoxyethoxy)ethoxy]-;benzodiazepine;CTK1D9933;Gyki Hcl;gyki52466;GYKI52466HCl;Gyki Hydrochloride;4-(8-Methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepine-5-yl)aniline;4-(8-Methyl-9H-1,3-dioxolo(4,5-H)(2,3)benzodiazepin-5-yl)benzenamine;1-(4-Aminophenyl)-4-methyl-7,8-(methylenedioxy)-5H-2,3-benzodiazepine;Benzenamine, 4-(8-methyl-9H-1,3-dioxolo(4,5-H)(2,3)benzodiazepin-5-yl)-;Lopac-G-119;PDSP2_001826;HY-103234;FT-0729241;Lopac0_000631;1-(4-aminophenyl)-4-methyl-7,8 -methylenedioxy-5H-2,3-benzodiazepine;NCGC00015463-08;BRD-K24240364-003-02-1;4-(8-Methyl-9H-1,3-dioxolo(4,5-h)(2,3)benzodiazepin-5-yl)benzenamine;BCP9000756;GYKI-2466;LFBZZHVSGAHQPP-UHFFFAOYSA-N;Benzenamine, 4-(8-methyl-9H-1,3-dioxolo(4,5-h)(2,3)benzodiazepin-5-yl)-;UNII-471V8NZ5X3;GYKI 52466 HCl;4-(8-methyl-9h-[1,3]dioxolo[4,5-h][2,3]benzodiazepin-5-yl)aniline;C17H15N3O2.HCl;CCG-204719;NCGC00015463-02;4-{13-methyl-4,6-dioxa-11,12-diazatricyclo[7.5.0.0^{3,7}]tetradeca-1(9),2,7,10,12-pentaen-10-yl}aniline;SDCCGSBI-0050612.P002;NCGC00025169-02;471V8NZ5X3;PDSP1_001843;AKOS030582785;NCGC00025169-01;4-(8-Methyl-9H-1,3-dioxa-6,7-diaza-cyclohepta[f]inden-5-yl)-phenylamine;SCHEMBL194854;GYKI53784;Tocris-1454;BCP02050;GYKI52466;CS-0025672;Gyki-52466;4-(8-methyl-9H-[1,3]dioxolo[4',5':4,5]benzo[1,2-d][1,2]diazepin-5-yl)aniline;NCGC00015463-04;NCGC00015463-03;NCGC00015463-01;GYKI 52466;CHEBI:79560;1-(p-Aminophenyl)-4-methyl-7,8-methylenedioxy-5H-2,3-benzodiazepine hydrochloride;CHEMBL275006;HB0311;4-(8-Methyl-9H-1,3-dioxa-6,7-diaza-cyclohepta[f]inden-5-yl)-phenylamine (GYKI 52466);GTPL4210;102771-26-6;Q5515088;BDBM50048389;4-(8-methyl-9h-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)-benzenamine hydrochloride;DTXSID40145500;Benzenamine, 4-(8-methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)-
SMILES: CC1CC2C=C3OCOC3=CC=2C(C2C=CC(N)=CC=2)=NN=1
Formula: C17H15N3O2
M.Wt: 293.3199
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: For the detailed information of GYKI 52466 dihydrochloride, the solubility of GYKI 52466 dihydrochloride in water, the solubility of GYKI 52466 dihydrochloride in DMSO, the solubility of GYKI 52466 dihydrochloride in PBS buffer, the animal experiment (test) of GYKI 52466 dihydrochloride, the cell expriment (test) of GYKI 52466 dihydrochloride, the in vivo, in vitro and clinical trial test of GYKI 52466 dihydrochloride, the EC50, IC50,and Affinity of GYKI 52466 dihydrochloride, Please contact DC Chemicals.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC5061 GYKI 52466 dihydrochloride GYKI 52466 dihydrochloride is a selective non-competitive AMPA receptor antagonist (IC50 values are 10-20, ~ 450 and >> 50 μM for AMPA- , kainate- and NMDA-induced responses respectively). Skeletal muscle relaxant and orally-active anticonvulsant.
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