| DCAPI1107 |
Deferasirox (Exjade)
Featured
|
Deferasirox (Exjade) |
|
| DC8481 |
Delanzomib(CEP-18770)
Featured
|
Delanzomib(CEP-18770) is a novel orally-active inhibitor of the chymotrypsin-like activity of the proteasome that down-modulates the nuclear factor-kappaB (NF-kappaB) activity. |
|
| DC11352 |
Delavirdine (mesylate) |
Delavirdine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that selectively inhibits HIV-1 reverse transcriptase over DNA polymerase α and δ in vitro (IC50s = 0.26, 440, and >550 μM, respectively). |
|
| DC8897 |
Delavirdine |
Delavirdine(U 90152) is a potent non-nucleoside reverse transcriptase inhibitor (NNRTI). |
|
| DC11890 |
Delgocitinib
Featured
|
Delgocitinib (JTE-052, LEO 124249) is a potent, selective, orally active, pan-JAK inhibitor with IC50 of 2.8, 2.6, 13 and 58 nM for JAK1,2,3 and Tyk2, respectively. |
|
| DC10612 |
Delpazolid (LCB01-0371)
Featured
|
Delpazolid (LCB01-0371) is a new oxazolidinone with cyclic amidrazone. |
|
| DC10559 |
Derazantinib (ARQ 087)
Featured
|
Derazantinib (Derazantinib) is an ATP competitive tyrosine kinase inhibitor; exhibits potent activity against FGFR1-3 chondrocytes with IC50s of 4.5, 1.8, and 4.5 nM, respectively. |
|
| DC9604 |
Desogestrel
Featured
|
Desogestrel(Org-2969) is a third-generation 19-nortestosterone derivative progestogen; is contained in many oral contraceptive preparations, both combined (COCs) to ethinyl-estradiol (EE) or alone in a progestin-only pill (POP). |
|
| DCAPI1475 |
Dexrazoxane Hydrochloride |
Dexrazoxane Hydrochloride |
|
| DC9414 |
DGAT-1 inhibitor 2 |
DGAT-1 inhibitor 2 is an effective inhibitor of DGAT-1;antiobesity agents.
|
|
| DC9551 |
Difluprednate
Featured
|
Difluprednate(Durezol) is a corticosteroid, approved difluprednate for the treatment of post-operative ocular inflammation and pain.
|
|
| DCAPI1152 |
Diltiazem HCl (Tiazac) |
Diltiazem HCl (Tiazac) |
|
| DC10446 |
(3R,4S,5S)-tert-butyl 3-Methoxy-5-Methyl-4-(MethylaMino)heptanoate hydroc hloride
Featured
|
Diltiazem hydrochloride is a calcium ion influx inhibitor (slow channel blocker or calcium antagonist). |
|
| DC7114 |
Dinaciclib (SCH727965)
Featured
|
Dinaciclib (SCH727965) is a novel and potent CDK inhibitor for CDK2, CDK5, CDK1 and CDK9 with IC50 of 1 nM, 1 nM, 3 nM and 4 nM, respectively. |
|
| DC9434 |
DMP 777 |
DMP 777(L-694458) is a potent, selective, and orally active human leukocyte elastase (HLE) inhibitor.
|
|
| DC9588 |
Dofequidar (fumarate) |
Dofequidar fumarate(MS-209 fumarate), an orally active quinoline compound, has been reported to overcome MDR by inhibiting ABCB1/P-gp, ABCC1/MDR-associated protein 1, or both.
|
|
| DC7273 |
Dolutegravir
Featured
|
Dolutegravir (DTG, GSK1349572) is an integrase inhibitor(IC50= 2.7 nM), modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H. |
|
| DC10250 |
Dolutegravir Sodium
Featured
|
Dolutegravir is a HIV integrase inhibitor with IC50 of 2.7 nM. |
|
| DC11103 |
Tavapadon
Featured
|
Tavapadon is a potent, orally-bioavailable, selective partial agonist of the dopamine D1 and D5 receptors. |
|
| DC9308 |
Doravirine (MK-1439)
Featured
|
Doravirine (MK-1439) is a non-nucleoside reverse transcriptase inhibitor. |
|
| DC4157 |
Dovitinib (TKI258, CHIR258)
Featured
|
Dovitinib (TKI258, CHIR258) is a novel multi-target inhibitor for Flt3, c-Kit, FGFR1/3, VEGFR1/2/3, PDGFRα/β with IC50 of 1 nM, 2 nM, 8 nM/9 nM and 10 nM/13 nM/8 nM, 210 nM/27 nM respectively. |
|
| DC10313 |
Dovitinib lactate |
Dovitinib(CHIR-258; TKI258) lactate is a potent inhibitor of fibroblast growth factor receptor 3 (FGFR3) with an IC50 of 5 nM. |
|
| DCAPI1241 |
Doxercalciferol (Hectorol)
Featured
|
Doxercalciferol is a synthetic vitamin D2 analog, suppressing parathyroid synthesis and secretion, used to treat secondary hyperparathyroidism and metabolic bone disease. |
|
| DCAPI1457 |
Dronedarone Hydrochloride |
Dronedarone is a Class III antiarrhythmic and a multi-channel blocker for atrial fibrillation. It blocks potassium and sodium and is a calcium channel protein inhibitor. |
|
| DC11726 |
Milademetan
Featured
|
Milademetan (DS-3032) is a specific and orally active MDM2 inhibitor for the research of acute myeloid leukemia (AML) or solid tumors. Milademetan (DS-3032) induces G1 cell cycle arrest, senescence and apoptosis. |
|
| DC11233 |
DS-8500a |
DS-8500a (DS8500a) is a novel potent, selective, orally available GPR119 agonist with EC50 of 51.5 nM in human GPR119-expressing CHO-K1 cells, displays no significant effect on 66 receptors, channels, or transporters. |
|
| DC11409 |
DSM265
Featured
|
DSM265 is a PfDHODH inhibitor with an IC50 of 8.9 nM. DSM265 can also inhibit the growth of P. falciparum 3D7 parasites with an EC50 of 4.3 nM. |
|
| DC8277 |
E-2012
Featured
|
E 2012 is a potent γ-secretase modulator. |
|
| DC8404 |
E3330
Featured
|
E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity. |
|
| DC7128 |
Lucitanib(E3810)
Featured
|
E-3810 is a novel dual inhibitor targeting human vascular endothelial growth factor receptors (VEGFRs) and fibroblast growth factor receptors (FGFRs) with antiangiogenic activity. |
|
