AZ-27

  Cat. No.:  DC11771  
Chemical Structure
1516772-44-3
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More than 5000 active chemicals with high quality for research!
Field of application
A potent non-nucleoside RSV L-protein polymerase inhibitor with EC50 of 0.01 uM and 1.3 uM for RSV A2 and RSV B-WST, respectively.
Cas No.: 1516772-44-3
Chemical Name: 6-(4-(2-(2-oxa-7-azaspiro[3.5]nonan-7-yl)nicotinamido)benzoyl)-N-cyclopropyl-5,6-dihydro-4H-benzo[b]thieno[2,3-d]azepine-2-carboxamide
Synonyms: AZ27;AZ 27
SMILES: N(C(=O)C1=CC=C(NC(=O)C2=C(N3CCC4(COC4)CC3)N=CC=C2)C=C1)1CCC2C=C(C(NC3CC3)=O)SC=2C2=CC=CC=C12
Formula: C36H35N5O4S
M.Wt: 633.767
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: A potent non-nucleoside RSV L-protein polymerase inhibitor with EC50 of 0.01 uM and 1.3 uM for RSV A2 and RSV B-WST, respectively; exhibits high potency against the RSV A subtype (average EC50=24±9 nM) than against the B subtype (average EC50=1.0±0.28 uM); shows no cytotoxicity.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC47013 (S)-Enzaplatovir (S)-Enzaplatovir ((S)-BTA-C585) is the S-enantiomer of Enzaplatovir. (S)-Enzaplatovir shows antiviral activities with an EC50 of 56 nM for respiratory syncytial viral (RSV) (patent WO2011094823A1 compound 77).
DC41364 ent-11β-Hydroxyatis-16-ene-3,14-dione ent-11β-Hydroxyatis-16-ene-3,14-dione (compound 11) is a diterpenoid from the fresh roots of Euphorbia jolkinii. ent-11β-Hydroxyatis-16-ene-3,14-dione has anti-RSV activity.
DC40330 Quercetin pentaacetate Quercetin pentaacetate could interact with F-protein with lower binding energy and better stability to block viral adhesion. Quercetin pentaacetate interacts with RSV and inhibit the viral adhesion on cell surface.
DC9618 TMC353121 TMC353121 is a potent RSV fusion inhibitor with pEC50 of 9.9(t1/2 in lung = 25 h).
DC10435 RSV604 racemate RSV604 racemate is a racemic mixture, shows less potency against strains of respiratory syncytial virus (RSV) than the S-isomer.
DC11774 YM-53403 A specific anti-respiratory syncytial virus (RSV) agent with EC50 of 0.2 uM in plaque reduction assays.
DC11773 BI Compound D A potent non-nucleoside RSV L-protein polymerase inhibitor with IC50 of 89 nM.
DC11771 AZ-27 A potent non-nucleoside RSV L-protein polymerase inhibitor with EC50 of 0.01 uM and 1.3 uM for RSV A2 and RSV B-WST, respectively.
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