BI Compound D

  Cat. No.:  DC11773  
Chemical Structure
851658-10-1
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More than 5000 active chemicals with high quality for research!
Field of application
A potent non-nucleoside RSV L-protein polymerase inhibitor with IC50 of 89 nM.
Cas No.: 851658-10-1
Chemical Name: 4-Amino-8-(3-((3,4-dimethoxyphenethyl)amino)propyl)-6,6-dimethyl-2-(4-methyl-3-nitrophenyl)-1H-imidazo[4,5-h]isoquinoline-7,9(6H,8H)-dione
Synonyms: RSV L-protein inhibitor
SMILES: C(=O)1C2=C(C=C(N)C3N=C(C4=CC=C(C)C([N+]([O-])=O)=C4)NC=32)C(C)(C)C(=O)N1CCCNCCC1=CC=C(OC)C(OC)=C1
Formula: C32H36N6O6
M.Wt: 600.68
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: A potent non-nucleoside RSV L-protein polymerase inhibitor with IC50 of 89 nM; shows anti-RSV activity with IC50 of 57.6 nM and 47.8 nM for RSV A2 and RSV B-EST, respectively; shows weak cytotoxicity (CC50=600 nM).
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
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DC9618 TMC353121 TMC353121 is a potent RSV fusion inhibitor with pEC50 of 9.9(t1/2 in lung = 25 h).
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DC11774 YM-53403 A specific anti-respiratory syncytial virus (RSV) agent with EC50 of 0.2 uM in plaque reduction assays.
DC11773 BI Compound D A potent non-nucleoside RSV L-protein polymerase inhibitor with IC50 of 89 nM.
DC11771 AZ-27 A potent non-nucleoside RSV L-protein polymerase inhibitor with EC50 of 0.01 uM and 1.3 uM for RSV A2 and RSV B-WST, respectively.
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