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AMX-883

Cat. No.: DC68053 Featured

Chemical Structure

3102636-19-8

For research use only. We do not sell to patients.

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Field of application

AMX-883 a selective and orally active BRD9 molecular glue degrader that drives differentiation in acute myeloid leukaemia. AMX-883 shows selectivity over all other bromodomain containing proteins and proteome wide. AMX-883 does not employ the commonly used E3 ligases (cereblon, VHL) but instead drives degradation via DCAF16 as a targeted glue. AMX-883 can be used for the study of acute myeloid leukaemia (AML).

Chemicals Properties Biological activity Related products COA MSDS Datasheet

Cas No.:	3102636-19-8
Chemical Name:	AMX-883
Synonyms:	AMX883 ;AMX 883
Formula:	C₄₅H₅₈FN₅O₅
M.Wt:	767.97
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC68076	BG-BRD4-P07
DC68075	BRU-SHP2-P06
DC68074	LLY-ESR1-P05
DC68073	AST-AR-P04
DC68072	NOV-EP001
DC68071	JHU-MDM2-P03
DC68070	CAS-FAK-P02
DC68069	MDA-S24-P01
DC68068	TB-008
DC68067	ARV-863

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.