Veliflapon

  Cat. No.:  DC28965  
Chemical Structure
128253-31-6
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More than 5000 active chemicals with high quality for research!
Field of application
Veliflapon (BAY X 1005; DG-031) is an orally active and selective 5-lipoxygenase activating protein (FLAP) inhibitor. Veliflapon inhibits the synthesis of the leukotrienes B4 and C4.
Cas No.: 128253-31-6
Chemical Name: (R)-2-(4-(Quinolin-2-yl-methoxy)phenyl)-2-cyclopentylacetic acid
Synonyms: Bay X1005; Bay X-1005; Bay X 1005; DG 031; DG-031; DG031; Veliflapon;
Formula: C23H23NO3
M.Wt: 361.441
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
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MSDS_13016_DC28965_128253-31-6
COA
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Cat. No. Product name Field of application
DC28965 Veliflapon Veliflapon (BAY X 1005; DG-031) is an orally active and selective 5-lipoxygenase activating protein (FLAP) inhibitor. Veliflapon inhibits the synthesis of the leukotrienes B4 and C4.
DC28608 (S)-BI 665915 (S)-BI 665915 is an orally active oxadiazole-containing 5-lipoxygenase-activating protein (FLAP) inhibitor with an IC50 of 1.7 nM for FLAP binding. (S)-BI 665915 inhibits FLAP functional in human whole blood with an IC50 of 45 nM. (S)-BI 665915 demonstrates an excellent cross-species drug metabolism and pharmacokinetics (DMPK) profile and a dose-dependent inhibition of LTB4 production.
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