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GBD-9

  Cat. No.:  DC67332   Featured
Chemical Structure
2864408-92-2
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More than 5000 active chemicals with high quality for research!
Field of application
GBD-9 is a dual-mechanism degrader that effectively targets BTK and GSPT1 by recruiting the E3 ligase cereblon (CRBN). It functions both as a PROTAC molecule to degrade BTK and as a molecular glue to induce GSPT1 degradation. GBD-9 demonstrates potent inhibition of cancer cell growth.
Cas No.: 2864408-92-2
Chemical Name: GBD-9
Synonyms: PD173370;EX-A8456
SMILES: O=C(CCCCCCCCNC1C=CC2C(N(C(C=2C=1)=O)C1C(NC(CC1)=O)=O)=O)N1CCC[C@H](C1)N1C2C(=C(N)N=CN=2)C(C2C=CC(=CC=2)OC2C=CC=CC=2)=N1
Formula: C44H47N9O6
M.Wt: 797.90
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
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