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PZ703b

  Cat. No.:  DC47361   Featured
Chemical Structure
2471970-56-4
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More than 5000 active chemicals with high quality for research!
Field of application
PZ703b is highly potent in killing BCL-XL dependent, BCL-2 dependent, and BCL-XL/BCL-2 dual-dependent cells in an E3 ligase (VHL)-dependent fashion.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 2471970-56-4
Chemical Name: INDEX NAME NOT YET ASSIGNED
Synonyms: PZ703b
SMILES: C(N1CCN(C2C=CC(C(=O)NS(C3C=CC(N[C@@H](CSC4C=CC=CC=4)CCN4CCOCC4)=C(S(=O)(=O)C(F)(F)F)C=3)(=O)=O)=CC=2)CC1)C1C[C@](C)(CNC(=O)CCCCCCCCC(=O)N[C@@H](C(C)(C)C)C(N2C[C@H](O)C[C@H]2C(=O)N[C@H](C2C=CC(C3=C(N=CS3)C)=CC=2)C)=O)CCC=1C1C=CC(Cl)=CC=1
Formula: C80H102ClF3N10O11S4
M.Wt: 1600.43450498581
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
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MSDS_31213_DC47361_2471970-56-4
COA
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Cat. No. Product name Field of application
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DC67029 KT-413 KT-413 (example I-3) is a potent IRAK degrader.
DC65810 KT-333 KT-333 is a first-in-class molecular glue that induces ​selective degradation of STAT3 via the ubiquitin-proteasome system by simultaneously engaging ​STAT3 and the VHL E3 ligase. This novel mechanism enables potent ​STAT3 depletion with minimal off-target effects, demonstrating strong ​anti-tumor activity in hematologic malignancies.
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