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(S)-Amisulpride

  Cat. No.:  DC47270   Featured
Chemical Structure
71675-92-8
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More than 5000 active chemicals with high quality for research!
Field of application
(S)-Amisulpride (Esamisulpride) is a potent dopamine D2/D3 receptor antagonist. (S)-Amisulpride is an antagonist at the 5-HT7 receptor with a KI of 900 nM. (S)-Amisulpride has antipsychotic and antidepressant effects.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 71675-92-8
Chemical Name: Benzamide,4-amino-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-5-(ethylsulfonyl)-2-methoxy-
Synonyms: Benzamide,4-amino-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-5-(ethylsulfonyl)-2-methoxy-;S-Amisulpride;Benzamide,4-amino-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulfonyl)-2-methoxy-, (S)-;S-(-)-Amisulpride;4-Amino-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-5-(ethylsulfonyl)-2-methoxybenzamide
SMILES: CCN1CCCC1CNC(C1C=C(S(CC)(=O)=O)C(N)=CC=1OC)=O
Formula: C17H27N3O4S
M.Wt: 369.47898
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC73426 F17464 F17464 is a dopamine D 3 receptor preferential antagonist exhibiting high affinity for human dopamine receptor subtype 3 (hD3) (Ki=0.17 nM) and 5-HT1a (Ki=0.16 nM) and a >50 fold lower affinity for the human dopamine receptor subtype 2 short and long form
DC73421 ASP4345 ASP4345 (ASP-4345) is a potent, selective positive allosteric modulator of the dopamine type 1 (D1) receptor that selectively binds to, and enhances the activity of, D1 receptors.
DC72808 UCM-1306 UCM1306 is a potent and orally active human dopamine D1 receptor allosteric modulator (PAM). UCM-1306 increases the endogenous dopamine (DA) maximal effect both in human and mouse D1 receptors. UCM-1306 is not only for improving motor symptoms but also for addressing the key comorbid cognitive impairment associated with long-term Parkinson’s disease (PD).
DC47683 Mesdopetam hemitartrate Mesdopetam (IRL790) hemitartrate is a dopamine D3 receptor antagonist (Ki=90 nM; IC50=9.8 μM for human recombinant D3 receptor) with psychomotor stabilizing properties. Mesdopetam hemitartrate is used for the research of motor and psychiatric complications in Parkinson disease.
DC47270 (S)-Amisulpride (S)-Amisulpride (Esamisulpride) is a potent dopamine D2/D3 receptor antagonist. (S)-Amisulpride is an antagonist at the 5-HT7 receptor with a KI of 900 nM. (S)-Amisulpride has antipsychotic and antidepressant effects.
DC46840 Mesdopetam Mesdopetam (IRL790) is an orally active and low toxicity dopamine D3 receptor antagonist. Mesdopetam can be used for the research of Parkinson's disease (PD).
DC8859 SKF38393 HCl SKF38393 HCl is a selective dopamine D1/D5 receptor agonist.
DC12316 PD-168077 maleate PD-168077 maleate is a selective dopamine D4 receptor agonist, with a Ki of 9 nM.
DC11103 Tavapadon Tavapadon is a potent, orally-bioavailable, selective partial agonist of the dopamine D1 and D5 receptors.
DC7991 8-​Chloro-​11-​(4-​methyl-​1-​piperazinyl)​-​5H-​dibenzo[b,e]​(1,4)​diazepine N-oxide Clozapine N-oxide is a major metabolite of Clozapine noted to decrease SR-2A (5-HT2 serotonin receptor) density in vitro.
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