Cat. No. | Product name | CAS No. |
DC8852 |
SW-044248
Featured
SW-044248 is a Novel Inhibitor of Topoisomerase I Is Selectively Toxic for a Subset of Non-Small Cell Lung Cancer Cell Lines. |
522650-83-5 |
DC10965 |
SW076956
Featured
SW076956 is a small molecule that selectively disrupt Beclin 1/Bcl-2 binding as compared to Bax/Bcl-2 and Bim/Bcl-2 binding and induces autophagic flux at concentrations with minimal cytotoxicity. |
851717-83-4 |
DC12634 |
SW-100
Featured
SW-100 (SW100) is a potent, selective, brain penetrable HDAC6 inhibitor with IC50 of 2.3 nM, displays >1,000-fold selectivity over all other class I, II, and IV HDAC isoforms. |
2126744-35-0 |
DC24205 |
SY-1365
Featured
SY-1365 is a CDK7 inhibitor. In vitro, SY-1365 inhibited cell growth of many different cancer types at nanomolar concentrations. |
1816989-16-8 |
DC10900 |
Syk inhibitor II
Featured
Syk inhibitor II is a cell-permeable, pyrimidine-carboxamide compound that selectively and reversibly blocks Syk (IC50 = 41 nM) in an ATP-competitive manner. |
726695-51-8 |
DC10436 |
SYP-5
Featured
SYP-5 is a novel HIF-1 inhibitor, suppresses tumor cells invasion and angiogenesis. |
1384268-04-5 |
DC5105 |
Favipiravir (T-705)
Featured
T 705(Favipiravir) is a RNA-directed RNA polymerase NS5B inhibitor.T 705(Favipiravir) is useful for Antiviral agents. |
259793-96-9 |
DC8063 |
T-00127-HEV1
Featured
T-00127-HEV1 is a novel potent phosphoinositide kinases (PIK) inhibitor,T-00127-HEV1 inhibited PI4KB activity with a higher specificity for than other PI kinases. |
900874-91-1 |
DC9601 |
T0070907
Featured
T0070907 is a potent and selective PPARγ antagonist with IC50 of 1 nM; displays > 800-fold selectivity for PPARγ over PPARα and PPARδ. |
313516-66-4 |
DC9842 |
T0901317
Featured
T0901317 is a potent, high affinity liver X receptor (LXR) agonist (EC50 ~ 50 nM, Kd values are 7 and 22 nM for LXR-α and LXR-β respectively). |
293754-55-9 |
DC21956 |
T16Ainh-A01
Featured
T16Ainh-A01 is an inhibitor of the calcium-activated chloride channel TMEM16A, inhibits Ca2+-activated Cl− channel (CACC) activity in TMEM16A-transfected FRT cells with IC50 of 1 uM; T16Ainh-A01 (1-30 uM) inhibited single calcium (Ca2+)-activated chloride (Cl−) channels and whole cell currents activated by 500 nM free Ca2+; T16Ainh-A01 relaxed mouse thoracic aorta pre-contracted with methoxamine with an IC50 of 1.6 uM and suppressed the methoxamine concentration-effect curve; blocks calcium-activated chloride channels in vascular smooth muscle cells and relaxes murine and human blood vessels. |
552309-42-9 |
DC20124 |
T-26c
Featured
T-26c is highly potent and selective matrix metalloproteinase-13 (MMP-13) inhibitor with an IC50 of 6.75 pM and more than 2600-fold selectivity over the other related metalloenzymes. |
869296-13-9 |
DC11703 |
T-3775440 hydrochloride
Featured
T-3775440 hydrochloride is a novel potent, selecitve, irreversible LSD1 inhibitor with IC50 of 2.1 nM. |
1422535-52-1 |
DC12606 |
T-448
Featured
T-448 (T448) is a specific inhibitor of LSD1 enzyme activity, enhances H3K4 methylation in primary cultured rat neurons but has little impact on LSD1-GFI1B complex in human TF-1a erythroblasts. |
1597426-53-3 |
DC8024 |
T-5224
Featured
T-5224 is a selective inhibitor of c-Fos/activator protein (AP)-1, attenuates lipopolysaccharide-induced liver injury in mice. |
530141-72-1 |
DC10067 |
T-5601640(T56-LIMKi)
Featured
T56-LIMKi is a LIMK2 inhibitor that reduces phosphorylated cofilin, and induces disassembly of actin stress fibers in NF1-/- MEFs cells. |
924473-59-6 |
DC12534 |
T5910047
Featured
T5910047 (T-5910047) is a small molecule inhibitor of MyD88-dependent signaling pathways, disrupts MyD88 homodimeric formation; inhibits SEB-induced inhibition of cytokine production in PBMCs with IC50 of 2-10 uM, also inhibits SEA-induced pro-inflammatory cytokine production, shows no toxicity in primary cells up to 100 uM. |
950003-29-9 |
DC8058 |
T863
Featured
T863 is an orally active, selective and potent DGAT1 (Acyl-CoA:diacylglycerol acyltransferase 1) inhibitor |
701232-20-4 |
DC9301 |
TA-01
Featured
TA-01 induces cardiomyocyte differentiation from human embryonic stem cells following mesoderm induction at 1 μM. Inhibits cardiomyocyte differentiation at 5 μM. Potently inhibits CK1ε, p38α, and CK1δ (IC50 values are 6.4, 6.7 and 6.8 nM respectively). |
1784751-18-3 |
DC9300 |
TA-02
Featured
TA-02 induces cardiomyocyte differentiation from human embryonic stem cells following mesoderm induction. Potently inhibits p38α, CK1δ and CK1ε (IC50 values are 20, 32 and 32 nM respectively). |
1784751-19-4 |
DC22299 |
Tabersonine
Featured
Tabersonine is a terpene indole alkaloid found in the medicinal plant Catharanthus roseus. |
29479-00-3 |
DC5901 |
Tadalafil
Featured
Tadalafil is a potent and selective inhibitor of Phosphodiesterase-5 (PDE5) This compound prevents the breakdown of phosphodiesterases, many of which are used as secondary messengers. By preventing the breakdown of these messenger molecules, tadalafil can |
171596-29-5 |