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Cat. No.	Product Name	Field of Application
DC12030	BMS-986195 Featured	BMS-986195 is a potent, covalent, irreversible inhibitor of Bruton’s tyrosine kinase (BTK).
DC10924	BMS986202 Featured	BMS-986202 is a clinical Tyk2 inhibitor that binds to Tyk2 JH2 with IC50 of 0.19 nM and shows remarkably selectivity over other kinases including Jak family members.
DC10131	BMS-986205(Linrodostat) Featured	BMS-986205 is an optimized indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor, is well tolerated with potent pharmacodynamic activity, alone and in combination with nivolumab in advanced cancers in a phase 1/2a trial
DC23998	BMX-IN-1 Featured	BMX-IN-1 is a selective, irreversible inhibitor of bone marrow tyrosine kinase on chromosome X (BMX) that targets Cys496 in the BMX ATP binding domain with an IC50 of 8 nM, also targets the related Bruton’s tyrosine kinase (BTK) with an IC50 value of 10.4 nM, but is more than 47-656-fold less potent against Blk, JAK3, EGFR, Itk, or Tec activity.
DC7377	BMY 7378 Featured	BMY 7378 is a multi-targeted inhibitor of α2C-adrenoceptor and α1D-adrenoceptor with pKi of 6.54 and 8.2, respectively, and acts as a mixed agonist and antagonist for 5-HT1A receptor with pKi of 8.3.
DC7773	BNC-105 Featured	BNC105 is a novel tubulin polymerization inhibitor that selectively disrupts tumor vasculature and displays single-agent antitumor efficacy.
DC22037	Bobcat339 Featured	Bobcat339 (Bobcat 339) is a novel cytosine-based TET enzyme inhibitor with IC50 of 33 uM (TET1) and 73 uM (TET2), but not DNMT3a, does not inhibit the DNA methyltransferase DNMT3a.
DC23218	BOC-D-FMK Featured	BOC-D-FMK is a cell-permeable, irreversible, broad spectrum caspase inhibitor, inhibits apoptosis stimulated by TNF-α with IC50 of 39 uM.
DC5077	Boceprevir(EBP 520; SCH 503034 ) Featured	Boceprevir(EBP 520; SCH 503034 ) is useful for Anti HCV.
DC8073	Bohemine Featured	Bohemine is a synthetic, cell-permeable, cyclin-dependent kinase inhibitor.
DC1027	Bortezomib (Velcade,MG-341,PS-341) Featured	Bortezomib is a potent 20S proteasome inhibitor with Ki of 0.6 nM.
DC21869	Borussertib Featured	Borussertib is a potent, first-in-class, covalent-allosteric AKT inhibitor.
DC12405	BOS172722 Featured	BOS172722 (BOS-172722) is a potent, selective MPS1 kinase inhibitor with biochemical IC50 of 11 nM, 100-fold selectivity over CDK2.
DC5164	Bosutinib (SKI-606) Featured	Bosutinib is a synthetic quinolone derivative and dual kinase inhibitor that targets both Abl and Src kinases with potential antineoplastic activity.
DC8040	STAT3 Inhibitor XVIII, BP-1-102 Featured	BP-1-102 is a potent, orally bioavailable and selective STAT3 inhibitor.BP-1-102 could enhance the transfection efficiency to 2-fold to 5-fold of Lipofectamine 3000 and LNP, all of which are currently approved for clinical use in the treatment of the most common malignant tumors.
DC8883	BP897 Featured	BP897 is a partially selective D3 dopamine receptor agonist.
DC12608	BPN14770 Featured	BPN14770 (BPN-14770) is an allosteric inhibitor of phosphodiesterase 4D (PDE4D) with IC50 of 7.8 and 7.4 nM for human PDE4D7 and PDE4D3 respectively, displays 16-fold less potent against monomeric form of PDE4D lacking the UCR1 dimerization domain (PDE4D2
DC8294	BPR1J-097 Featured	BPR1J-097 is a novel small molecule FLT-3 inhibitor(IC50=11±7 nM) with promising in vivo anti-tumour activities; inhibits FLT-3 D835Y with an IC50 of 3 nM.
DC7951	Glutaminase Inhibitor II, BPTES Featured	BPTES is a selective inhibitor of Glutaminase GLS1 (KGA)
DC10618	BPTU Featured	BPTU is an Allosteric antagonist of P2Y1 (EC50 = 0.06-0.3 μM).
DC8392	BQ-123 Featured	BQ-123 is a selective endothelin A receptor (ETA) antagonist with IC50 of 7.3 nM. Phase 2.
DC7542	BQ-788 Featured	BQ-788 sodium salt is a potent, selective ETB receptor antagonist (IC50 = 1.2 nM for inhibition of ET-1 binding to human Girardi heart cells); poorly inhibited the binding to ET A receptors in human neuroblastoma cell line SK-N-MC cells (IC(50), 1300 nM).
DC10515	BQCA Featured	BQCA is a potent muscarinic M1 receptor positive allosteric modulator with selectivity for M1 over M2-M5.
DC8202	BQU57 Featured	BQU57 is a potent and selective GTPase Ral Inhibitor.
DC7809	BRACO19 trihydrochloride Featured	BRACO19 is a telomerase inhibitor that stabilizes G-quadruplexes, targeting telomeric G-quadruplexes, inducing DNA damage and cell-cycle arrest.
DC20323	Bractoppin Featured	Bractoppin is a potent, small-molecule chemical inhibitor that specific selectively blocks phosphopeptide recognition by the BRCA1 tBRCT domain with binding IC50 of 74 nM; shows no inhibition for recognition of cognate biotinylated phosphopeptides to the TOPBP1 tBRCT 7/8, or GRB2 SH2 proteins; engages BRCA1 tBRCT residues recognizing pSer in the consensus motif, pSer-Pro-Thr-Phe, plus an abutting hydrophobic pocket; inhibits substrate recognition detected by Förster resonance energy transfer, and diminishes BRCA1 recruitment to DNA breaks, in turn suppressing damage-induced G2 arrest and assembly of the recombinase, RAD51; selectively interrupts BRCA1 tBRCT-dependent signals evoked by DNA damage.
DC7775	Bradanicline (TC-5619) Featured	Bradanicline (TC-5619) is an experimental pharmaceutical drugthat acts as a partial agonist at the α7 subtype of the neural nicotinic acetylcholine receptors.
DC7718	B-Raf IN 1 Featured	B-Raf IN 1 is a highlt potent and selective B-Raf inhibitor with IC50 of 24 nM; equipotent against c-Raf (IC50= 25 nM).
DC8921	B-Raf inhibitor 1 Featured	B-Raf inhibitor 1 is a potent and selective B-Raf inhibitor with cell IC50s of 0.31 uM and 2 nM for A375 proliferation and A375 p-ERK respectively.
DC7008	BRAF inhibitor Featured	BRAF inhibitor is a potent BRAF inhibitor.

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