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Cat. No. Product name CAS No.
DC60373 HGT4003 Featured

1415795-37-7
DC60375 Dlin-C-DAP Featured

1169768-13-1
DC60376 Ethanol, 2-[[(3b)-cholest-5-en-3-yl]oxy]-, 4-methylbenzenesulfonate Featured

30656-75-8
DC60377 Compound 32 Featured

1361106-13-9
DC60378 Y-DLenDMA Featured

1260141-95-4
DC60379 HisChol Featured

449791-79-1
DC60380 KL22 Featured

1413010-97-5
DC60381 KUO Featured

1413010-89-5
DC60382 Dimyristyloxypropyla mine Featured

396727-98-3
DC60383 CpUnDMA( PCUnDMA) Featured

908860-83-3
DC60384 CTAP Featured

CTAP is a selective μ opioid receptor antagonist that displays selectivity over δ opioid and somatostatin receptors. CTAP is brain penetrant and active in vivo.

103429-32-9
DC60385 DLin-S-DMA Featured

1169768-15-3
DC60386 DLin-2-DMAP Featured

1169768-10-8
DC60387 Dioley la mi ne-A- succinyl paromomycin DOSP Featured

959664-11-0
DC60388 C2-DLinDMA Featured

1192257-55-8
DC60389 GAP-DLRIE Featured

208040-06-6
DC60390 DLin-K-C4-DMA Featured

1217306-47-2
DC83230 TNT-b10 Featured

TNT-b10 is a novel Lipid-like compound suitable for delivery of siRNA and mRNA both in vitro and in vivo TNT-b10 LLNs was more than 10-fold more potent than TNT-a10 LLNs formulated under the same condition.

DC72591 OUL232 Featured

OUL232 is a potent inhibitor of mono-ARTs PARP7, PARP10, PARP11, PARP12, PARP14, and PARP15. OUL232 is the most potent PARP10 inhibitor described to date (IC50=7.8 nM), as well as the first PARP12 inhibitor ever reported.

943119-42-4
DC72592 Zelasudil Featured

Zelasudil is a Rho-associated (ROCK) kinase inhibitor. Zelasudil has a ROCK2 binding affinity.

2365193-22-0
DC72598 EG-011 Featured

EG-011 is the first-in-class and potent Wiskott-Aldrich syndrome protein (WASP) activator. EG-011 activates the auto-inhibited form of WASP with strong actin polymerization. EG-011 has selective anti-tumor activity in lymphomas.

2377113-41-0
DC72617 LAS190792 Featured

LAS190792 (AZD8999) is a potent muscarinic antagonist and β2-adrenoceptor agonist with pIC50 8.9, 8.8, 8.8, 9.2, 8.2, 7.5, 9.1, 5.6 for M1, M2, M3, M4, M5, β1, β2, β3, respectively. LAS190792 can be used as a bronchodilator.

1347232-69-2
DC72649 Nimucitinib Featured

Nimucitinib is a Janus kinase (JAK) inhibitor.

2740557-24-6
DC72651 SG-094 Featured

SG094 is a potent TPC2 inhibitor with antiproliferative effects. SG-094 can be used for the research of cancer.

2922283-37-0
DC72663 SW222746 Featured

SW222746 (SW 222746) is a potent selective, orally active inhibitor of 15-Prostaglandin dehydrogenase (15-PGDH) with IC50 of 3 nM.

2241676-74-2
DC72666 BMS-820132 Featured

BMS-820132 (BMS 820132) is potent, selective, partial glucokinase (GK) activator with AC50 of 29 nM.

1001419-18-6
DC72686 SP 600125, negative control Featured

SP 600125, negative control (SPM1) is an alkyl derivative of pyrazoloanthrone, which can be used as a negative control for SP600125.

54642-23-8
DC72699 Compound C108 Featured

Compound C108 is a G3BP2 inhibitor. Compound C108 also targeted stress granule-associated proteins and Gtpase-activating protein (SH3 domain) binding protein 2. Compound C108 potently inhibits esophageal squamous cell carcinoma (ESCC) cell metastasis.

15533-09-2
DC72701 mono-Pal-MTO Featured

mono-Pal-MTO is a palm oil-based lipid produced by combining the anticancer drug mitoxantrone (MTO) with palmitoleic acid. When nanoparticles of mono-Pal-MTO and di-Pal-MTO are combined in a molar ratio of 1:1, they show effective siRNA cell delivery and enhance anticancer activity.

1349197-89-2
DC72708 di-Pal-MTO Featured

di-Pal-MTO is a palm oil-based lipid produced by combining the anticancer drug mitoxantrone (MTO) with palmitoleic acid. When nanoparticles of mono-Pal-MTO and di-Pal-MTO are combined in a molar ratio of 1:1, they show effective siRNA cell delivery and enhance anticancer activity.

1349197-90-5
DC72718 S19-1035 Featured

S19-1035 is a highly potent and specific aldo-keto reductase 1C3 (AKR1C3) inhibitor. S19-1035 inhibits AKR1C3 with an IC50 value of 3.04 nM. S19-1035 can be used for the research of tumor.

DC72724 PTC258 Featured

PTC258 is a specific and orally active splicing modulator of Elongator complex protein 1 gene (ELP1). PTC258 increases the expression of ELP1 in vitro and in vivo. PTC258 is well tolerated in mouse model.

2476724-74-8
DC72726 HQ005 Featured

HQ005 is a potent CCNK degrader with an DC50 value of 0.041 µM. HQ005 is a molecular-glue degrader that mediates interactions between target proteins and components of the ubiquitin-proteasome system to cause selective protein degradation.

2750644-31-4
DC72738 YLF-466D Featured

YLF-466D is an AMPK activator that inhibits platelet aggregation with IC50 of 84 μM.

1273323-67-3
DC72741 BGB 15025 Featured

BGB-15025 is a potent and selective HPK1 inhibitor. It is used in the treatment of various cancers.

2766481-17-6
DC72747 Elenestinib Featured

Elenestinib (BLU-263) is a potent and orally active tyrosine kinase inhibitor. Elenestinib has the potential for the research of systemic mastocytosis (SM).

2505078-08-8
DC72750 GNE-9822 Featured

GNE-9822 is a potent, orally active and selective ITK inhibitor with a Ki value of 0.7 nM. GNE-9822 has good ADME properties. GNE-9822 can be used in research of asthma.

1557232-32-2
DC72751 CT52923 Featured

CT52923 is a selective, orally active platelet-derived growth factor receptor (PDGFR) antagonist. CT52923 also is an ATP-competitive inhibitor. CT52923 can be used for the research variety of pathological diseases, including atherosclerosis, glomerulonephritis, liver cirrhosis, pulmonary fibrosis, and cancer.

205256-55-9
DC72756 JQAD1 Featured

JQAD1 is a CRBN-dependent PROTAC that selectively targets EP300 for degradation. JQAD1 suppresses EP300 expression and the H3K27ac modification. JQAD1 induces apoptosis. JQAD1 can be used in research of cancer.

2417097-18-6
DC72765 Evocalcet Featured

Evocalcet (KHK7580) is an novel oral calcimimetic agent which acts via allosteric activation of the calcium sensing receptor (CaSR). Evocalcet (0, 20 and 60 nM) dose-dependently increases cytoplasmic [Ca2+] concentrations with an EC50 value of 92.7 nM in hCaR-HEK293 cells.

870964-67-3
DC72766 PF-07054894 Featured

PF-07054894 is a potent CCR6 antagonist. PF-07054894 targets G protein-coupled receptor (GPCR). PF-07054894 can be used in research of inflammatory bowel disease.

2413693-96-4
DC72770 Zongertinib Featured

Zongertinib is a potent tyrosine kinase inhibitor. Zongertinib can be used as an antineoplastic agent. Zongertinib also has been tested as pHER2 and EGFR inhibitor inhibiting a wide variety of cancers.

2728667-27-2
DC72773 Brigimadlin Featured

Brigimadlin is an E3 ubiquitin-protein ligase MDM-2 inhibitor. Brigimadlin serves as an antineoplastic agent.

2095116-40-6
DC72775 iJMJD6 Featured

iJMJD6(WL12) is an inhibitor of arginine demethylase JMJD6 with an IC50 value of 0.22 μM.

899548-78-8
DC72776 SD49-7 Featured

SD49-7 is an inhibitor of histone lysine-specific demethylase 4 (KDM4) with an IC50 of 0.19 µM.

54009-54-0
DC72777 DS-9300 Featured

DS-9300 is a potent, orally active, selective EP300/CBP HAT inhibitor with an IC50 value of 28 nM. DS-9300 has anticancer activity and can be used in prostate cancer disease research.

2259641-46-6
DC72779 RK-701 Featured

RK-701 is an highly selective and non-genotoxic inhibitor of G9a with IC50 value of 23-27 nM. RK-701 selectively up-regulates HbF, γ- Globin, BGLT3 expression, down-regulates H3K9me2 expression. RK-701 also has inhibition for BCL11A and ZBTB7A.

2648855-18-7
DC72785 TP0597850 Featured

TP0597850 is a selective inhibitor of MMP2 (IC50=0.22 nM). TP0597850 has a long MMP2 dissociation half-life (t1/2=265 min).

2642181-22-2
DC72788 AZD0095 Featured

AZD0095 is a selective and orally active MCT4 inhibitor (IC50: 1.3 nM). AZD0095 effectively inhibits the tumor growth in NCI-H358 xenograft in combination with Cediranib.

2750001-23-9
DC72794 Zidesamtinib Featured

Zidesamtinib (NVL-520) is a potent, selective, orally active and brain-penetrant inhibitor of diverse ROS1 fusions and resistance mutations, with IC50s of 0.7 and 7.9 nM for wild-type ROS1 and ROS1 G2032R, respectively, and spares TRK inhibition. Zidesamtinib can be used for the research of cancer.

2739829-00-4
DC72800 PESTAHIVIN Featured

PESTAHIVIN is a cell adhesion molecule inhibitor. HUN-7293 selectively inhibits the expression of three cell adhesion molecules (VCAM-1, ICAM-1 and E-selectin) (IC50=1-24 nM). HUN-7293 can be used in the study of inflammatory and autoimmune diseases characterized by overexpression of cell adhesion molecules.

165754-55-2
DC60391 WEHL-03 Featured

15827-80-2
DC60392 WEHL-04 Featured

114744-51-3
DC60393 T3 Featured

5817-39-0
DC60394 PU-WS13 Featured

PU-WS13 is a selective Grp94 inhibitor, with an EC50 of 0.22 μM.

1454619-14-7
DC60395 Meclozine Featured

Meclozine is a histamine H1 antagonist used in the treatment of motion sickness, vertigo, and nausea during pregnancy and radiation sickness.

569-65-3
DC60396 (S)-SHA 68 Featured

847555-75-3
DC60397 1-Methyl-3-amino-4-cyanopyrazole Featured

21230-50-2
DC60398 TFMT Featured

TFMT (Trifluoromethyl-tubercidin) inhibits methyltransferase 1 (MTr1) through interaction at its S-adenosyl-l-methionine binding pocket to restrict influenza virus replication. TFMT is active against influenza A virus (IAV) and influenza B virus (IBV) but not hazara virus (HAZV) or Issyk-Kul virus (ISKV).

1854086-05-7
DC60399 DT2216-isomer Featured

DT2216-isomer is an isomer of DT2216. Compared to DT-2216, DT2216-isomer has a S-chiral carbon which links to the nitrogen atom of the aniline group. DT2216 is a potent and selective Bcl-xL-specific degrader. DT2216 is highly active against Bcl-xL-dependent T cell lymphomas. DT2216 selectively killed various Bcl-xL-dependent TCL cells including MyLa cells in vitro. In vivo, DT2216 alone was highly effective against MyLa TCL xenografts in mice without causing significant thrombocytopenia or other toxicity. Furthermore, DT2216 combined with ABT199 (a selective Bcl-2 inhibitor) synergistically reduced disease burden and improved survival in a TCL PDX mouse model dependent on both Bcl-2 and Bcl-xL.

DC60400 Gramicidin S Featured

Gramicidin S is an anttiboitics. Gramicidin S reduces the cell number of planktonic cells within 20-40 min at a concentration of 40-80 μg/mL. Gramicidin S kills the cells of pre-grown biofilms at concentrations of 100-200 μg/mL, such that no re-growth is possible. The translocation of the peptide into the cell interior and its complexation with intracellular nucleotides, including the alarmon ppGpp, can explain its anti-biofilm effect. The successful treatment of persistently infected root canals of two volunteers confirms the high effectiveness of GS. The broad Gramicidin S activity towards resistant, biofilm-forming E. faecalis suggests its applications for approval in root canal medication.

113-73-5
DC60401 DL-AP-3 Featured

DL-AP-3, or AP-3 is a Potent metabotropic glutamate receptor antagonist.

20263-06-3
DC60402 Dov-Val-Dil-OH Featured

Dov-Val-Dil-OH is a useful chemical intermediate for synthesis of auristatin-related compounds, such as Monomethyl auristatin E (MMAE), Auristatins are antimitotic agents which inhibits cell division by blocking the polymerisation of tubulin.

133120-90-8
DC60403 Bacteriopheophytin Featured

Bacteriopheophytin, also known as Bacteriopheophytin a, is a Pigment which is the degradation product of bacteriochlorophyll.

17453-58-6
DC83220 ALC-0315 analgous-1 Featured

ALC-0315 analgous-1 is an ethanolamine ionizable lipid with both ester bonds located adjacent to C8 relative to the amine head. The introduction of ester linkages can improve the clearance of the lipid in the liver. This compound is analgous to ALC-0315.

2430034-17-4
DC60405 C13-112-tri-tail Featured

C13-112-tri-tail is an ionizable lipid molecule containing a polar amino alcohol head group, three hydrophobic carbon-13 tails, and a PEG2 linker. The lipoid can be formulated into a lipid nanoparticle (LNP) to deliver anionic substrates in vitro and in vivo. This includes siRNA to induce gene silencing in a sequence-specific manner, CAS9 mRNA, and cytotoxic proteins. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

1381861-96-6
DC60406 C13-113-tri-tail Featured

C13-113-tri tail is an ionizable lipid molecule containing a polar amino alcohol head group, three hydrophobic carbon-13 tails, and a tertiary amine linker. The lipoid can be formulated into a lipid nanoparticle (LNP) to deliver anionic substrates in vitro and in vivo. This includes siRNA to induce gene silencing in a sequence-specific manner, CAS9 mRNA, and cytotoxic proteins. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

1381861-86-4
DC60407 C13-112-tetra-tail Featured

C13-112-tetra-tail is an ionizable lipid molecule containing a polar amino alcohol head group, four hydrophobic carbon-13 tails, and a PEG2 linker. The lipoid can be formulated into a lipid nanoparticle (LNP) to deliver anionic substrates in vitro and in vivo.

1381861-92-2
DC60408 C13-113-tetra-tail Featured

C13-113-tetra tail is an ionizable lipid molecule containing a polar amino alcohol head group, four hydrophobic carbon-13 tails, and a tertiary amine linker.

1381861-97-7
DC60409 14:0 TAP Featured

TAP (14:0) A cationic lipids that can be used for drug delivery, gene transfection and vaccine delivery. TAP has been proven to be efficient for in vitro and in vivo transfection applications, which makes it one of the most widely used cationic lipids for gene transfection applications. Reagent grade, for research use only.

197974-74-6
DC60411 Boc-Val-Cit-PAB-PNP Featured

Boc-Val-Cit-PAB-PNP is useful and cleavable linker for ADC (antibody drug conjugate) synthesis.

870487-10-8
DC60412 VUN74640 Featured

VUN74640, also known as CCR6 antagonist 1, is a CCR6 antagonist. VUN74640 can be used in the research of autoimmune-mediated inflammatory diseases, such as inflammatory bowel diseases (IBDs). This product has no formal name at the moment.

588674-64-0
DC60413 Vc-MMAF Featured

MC-VC-PAB-MMAF, also known as MC-Val-Cit-PAB-MMAF and Vc-MMAF, is a MMAF (Monomethylauristatin F) derivative with a reactive linker have a maleimido functional group in the end. MC-VC-PAB-MMAF is a useful compound to make MMAF antibody drug conjugates for cancer treatment. MMAF is a potent tubulin polymerization inhibitor with antitumor activity.

863971-17-9
DC60414 WAY-111543 Featured

WAY-111543 is a bioactive chemical.

868269-74-3
DC60415 MitoBlock-6 Featured

MitoBlock-6 is an Augmenter of liver regeneration (ALR) inhibitor. MitoBloCK-6 attenuated the import of Erv1 substrates into yeast mitochondria and inhibited oxidation of Tim13 and Cmc1 in in vitro reconstitution assays.

303215-67-0
DC60416 SUN59716 Featured

SUN59716 is a key intermediate for chemical synthesis of cenobamate. This product has no formal name at the moment.

1259059-71-6
DC60417 EN106 Featured

EN106 is a potent inhibitor of FEMIB. EN106 targets FEM1B, an E3 ligase recently discovered as the critical component of the cellular response to reductive stress. By targeting C186 in FEM1B, EN106 disrupts recognition of the key reductive stress substrate of FEM1B, FNIP1.

757192-67-9
DC60418 16:0 TAP Featured

16:0 TAP is a cationic derivative of trimethylammonium linked with two 16-carbon fatty acid tails. 16:0 TAP is a cationic liposome-forming compound that may be used for transfection of DNA, RNA, and other negatively charged molecules into eukaryotic cells. Reagent grade, for research use only.

139984-36-4
DC60419 18:0 TAP Featured

18:0 TAP is a cationic derivative of trimethylammonium linked with two 18-carbon fatty acid tails. 18:0 TAP is a cationic liposome-forming compound that may be used for transfection of DNA, RNA, and other negatively charged molecules into eukaryotic cells. Reagent grade, for research use only.

220609-41-6
DC60420 18:1 TAP (DOTAP, MS Salt) Featured

18:1 TAP is a cationic liposome-forming compound that may be used for transfection of DNA, RNA, and other negatively charged molecules into eukaryotic cells. Reagent grade, for research use only.

144189-73-1
DC60421 DC-6-14 Featured

DC-6-14 is a cationic lipid that can be used for drug delivery, gene transfection and vaccine delivery. DC-6-14 may be used for research into in vitro and in vivo nucleic acid and protein delivery. Reagent grade, for research use only.

107086-76-0
DC60422 12:0 EPC (Cl Salt) Featured

12:0 EPC (Cl Salt) is a cationic derivatives of phospholipids consisting entirely of biological metabolites linked with two 12-carbon fatty acid tails. The lipid has low toxicity and is biodegradable. Reagent grade, for research use only.

474945-22-7
DC60423 14:0 EPC (Cl Salt) Featured

14:0 EPC (Cl Salt) is a cationic derivatives of phospholipids consisting entirely of biological metabolites linked with two 14-carbon fatty acid tails. The lipid has low toxicity and is biodegradable.

186492-53-5
DC60424 16:0 EPC (Cl Salt) Featured

16:0 EPC (Cl Salt) is a cationic derivatives of phospholipids consisting entirely of biological metabolites linked with two 16-carbon fatty acid tails. The lipid has low toxicity and is biodegradable. Reagent grade, for research use only.

328250-18-6
DC60425 18:0 EPC (Cl Salt) Featured

18:0 EPC (Cl Salt) is a cationic derivatives of phospholipids consisting entirely of biological metabolites linked with two 18-carbon fatty acid tails. The lipid has low toxicity and is biodegradable. Reagent grade, for research use only.

328268-13-9
DC60426 14:1 EPC (Tf Salt) Featured

14:1 EPC (Tf Salt) is a cationic derivatives of phospholipids consisting entirely of biological metabolites linked with two 14-carbon fatty acid tails with single alkene groups in each tail. The lipid has low toxicity and is biodegradable. Reagent grade, for research use only.

1246304-44-8
DC60427 18:1 EPC (Cl Salt) Featured

18:1 EPC (Cl Salt) is a cationic derivatives of phospholipids consisting entirely of biological metabolites linked with two 18-carbon fatty acid tails with single alkene groups in each tail. The lipid has low toxicity and is biodegradable. Reagent grade, for research use only.

474945-24-9
DC60428 16:0-18:1 EPC (Cl Salt) Featured

16:0-18:1 EPC (Cl Salt) is a cationic derivatives of phospholipids consisting entirely of biological metabolites linked with one 16-carbon fatty acid tail and one 18-carbon fatty acid tail with a single alkene group. The lipid has low toxicity and is biodegradable. Reagent grade, for research use only.

328250-19-7
DC60429 16:0 DAP Featured

16:0 DAP, 1,2-dipalmitoyl-3-dimethylammonium-propane, is a cationic lipid that can be used to formulate lipid nanoparticles (LNPs). 18:0 DAP also serves as a pH-sensitive transfection reagent. Reagent grade, for research use only.

96326-74-8
DC60431 DODAC Featured

7212-69-3
DC60432 DORI Featured

DORI, N-(2-hydroxyethyl)-N,N-dimethyl-2,3-bis(oleoyloxy)propan-1-aminium bromide, is an ionizable cationic lipid with lower cytotoxicity and high transfection efficiency. Reagent grade, for research use only.

153312-59-5
DC60433 DOBAQ Featured

DOBAQ, N-(4-carboxybenzyl)-N,N-dimethyl-2,3-bis(oleoyloxy)propan-1-aminium, is a cationic lipids with a quaternary amine and unsaturated hydrocarbon chains. DOBAQ also serves as a pH-sensitive transfection reagent. Reagent grade, for research use only.

1360461-69-3
DC60434 Bendamustine HCL Monohydrate Featured

1374784-02-7
DC60435 Belumosudil mesylate Featured

Belumosudil, also known as KD-025 and WHO11343, is an orally bioavailable inhibitor of ROCK-II that is greater than 200-fold selective over ROCK-I (IC50s = 105 nM and 24 µM, respectively). Belumosudil (SLx-2119; 40 µM) induces significant down-regulations of Tsp-1 and CTGF mRNA levels in PASMC.

2109704-99-4
DC60436 Eperison Hydrochloride Featured

Eperisone hydrochloride is a compound used in the treatment of musculoskeletal disorders as a muscle relaxant via blocking of calcium channels.

56839-43-1
DC60437 Tizanidine Featured

Tizanidine is a drug that is used as a muscle relaxant. It is a centrally acting α2 adrenergic agonist. It is used to treat the spasms, cramping, and tightness of muscles caused by medical problems such as multiple sclerosis, ALS, spastic diplegia, back pain, or certain other injuries to the spine or central nervous system.

51322-75-9
DC84101 Arcturus lipid 2 analog((Lipid 2,2 (9,9) 4C CH3)) Featured

Arcturus lipid 2 analog (Lipid 2,2 (9,9) 4C CH3) is an analog of Arcturus lipid 2((Lipid 2,2 (8,8) 4C CH3)) with chain adjusted to C9 instead of C8.

DC60438 17S-FD-895 Featured

17S-FD-895 is a tubulin polymerization inhibitor with marked antitumor activities.

2803326-64-7
DC84110 R-DOTAP(DOTAP R-isomer ) Featured

1,2-Dioleoyl-3(R)-trimethylammoniumpropane (R-DOTAP) is a cationic lipid and the more immunologically active isomer of DOTAP.Lipoplexes containing R-DOTAP and encapsulating siRNA targeting the gene encoding aromatase, CYP19A1, decrease aromatase activity in MCF-7 breast cancer cells.1 Vaccination with a peptide epitope from human papillomavirus (HPV) 16 protein E7 in R-DOTAP-containing liposomes induces IFN-γ production by CD8+ T cells and tumor-infiltrating lymphocytes (TILs) and decreases tumor size in a murine cervical cancer model.2 Subcutaneous immunization with recombinant influenza B hemagglutinin using R-DOTAP as an adjuvant increases IL-2 and IFN-γ production in CD4+ T cells isolated from mouse draining lymph nodes and spleen.

328250-28-8
DC60439 XC-DAPOL-CPBA Featured

191231-97-7
DC60440 2,3-Dimethyl-1,3,8-triazaspiro[4.5]dec-1-en-4-one hydrochloride Featured

1774899-05-6
DC65001 4A3-Cit Featured

4A3-Cit is an ionizable lipid used for the generation of lipid nanoparticles (LNPs). To investigate the role of unsaturated lipid tails in iLNPs, the nucleophilic amines were added to ester-based linkers, followed by Michael’s addition to the thiols to construct a library of 91 amino ionizable lipids. Such ionizable lipids were composed of an ionizable tertiary amine core, an ester-based degradable linker, and an alkylthiol tail periphery. Through in vitro and in vivo screening, the iLNPs with 4A3 core and citronellolbased (Cit) periphery can significantly increase endosome escape and delivery efficiency of mRNA, leading to 18-fold increase in protein expression compared with iLNPs without Cit periphery. Furthermore, the delivery efficiency of mRNA may be associated with the location/configuration of the unsaturated bond(s) in lipids. Although lipids with Cit periphery showed excellent membrane fusion ability to facilitate endosome escape, the fusion mechanism needs to be further clarified.

2768211-13-6
DC65004 G0-C14 Featured

G0-C14 is a cationic lipid-like compound alkyl-modified polyamidoamine (PAMAM) dendrimer. G0-C14 involves in the preparation of a series of macrophage-targeted nanoparticles (NPs). NPs can be used for drug and vaccine delivery[1][2].

1510653-27-6
DC65005 Diuron Featured

Diuron is a phenylurea herbicide that inhibits photosynthesis by preventing the formation of ATP and NADH. Diuron (2,500 ppm, dietary) increases the incidence of urinary bladder urothelial carcinomas in male and female mice by 73 and 27%, respectively.

330-54-1
DC65006 Metasilicic acid Featured

63231-67-4
DC65007 A2 Featured

131816-87-0
DC65008 tributylammonium pyrophosphate Featured

5975-18-8
DC65010 m-PEG11-alcohol Featured

m-PEG11-alcohol is a PEG derivative containing a hydroxyl group. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The hydrophilic PEG spacer increases solubility in aqueous media.

9004-74-4
DC65011 m-PEG3-CH2COOH Featured

m-PEG3-CH2COOH is a PEG-based based PROTAC linker can be used in the synthesis of PROTACs.

16024-60-5
DC65012 m-PEG4-CH2COOH Featured

m-PEG4-CH2COOH is a PEG-based based PROTAC linker can be used in the synthesis of PROTACs.

16024-66-1
DC65013 m-PEG6-CH2COOH Featured

m-PEG6-O-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

75427-75-7
DC65014 m-PEG8-CH2COOH Featured

m-PEG8-CH2COOH is a PEG--based PROTAC linker can be used in the synthesis of PROTACs.

102013-72-9
DC65015 m-PEG10-CH2COOH Featured

m-PEG10-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

908258-58-2
DC65016 AGPS-IN-2i Featured

AGPS-IN-2i is a novel inhibitor of alkylglyceronephosphate synthase (agps), specifically impairing epithelial to mesenchymal transition (emt) by modulating e-cadherin, snail and mmp2 expression levels.

2316782-88-2
DC65017 β-Glucuronidase-IN-1 Featured

β-Glucuronidase-IN-1 is a potent, selective, uncompetitive, and orally active E. coli bacterial β-glucuronidase inhibitor, exhibiting an IC50 and a Ki of 283 nM and 164 nM, respectively.

484006-66-8
DC65018 2-Formyl-3-hydroxybenzoic acid Featured

1243461-12-2
DC65019 Isolithocholic acid (β-Lithocholic acid) Featured

Isolithocholic acid (β-Lithocholic acid) is an isomer of Lithocholic acid. Isolithocholic acid, a bile acid, is formed by microbial metabolism of Lithocholic acid or Lithocholic acid 3α-sulfate.

1534-35-6
DC65020 (S)-2-fluoropropionic acid Featured

57965-29-4
DC65021 H2-Gamendazole Featured

H2-Gamendazole is a derivative of Lonidamine that reduces cyst formation in polycystic kidney disease and is used in autosomal dominant polycystic kidney disease research.

877768-84-8
DC65022 1,2,5-Oxadithiolane, 2,2,5,5-tetraoxide Featured

4378-87-4
DC65023 ACE-083 Featured

ACE083 is a Locally acting muscle-promoting agent

81080-10-6
DC65024 CPI-455 HCl Featured

2095432-28-1
DC65025 Fluoromethanesulfonyl chloride Featured

42497-69-8
DC65026 1H-Phenalene Featured

203-80-5
DC65027 9H-Purin-6-amine, 2-chloro-N-[(4,6-dimethyl-3-pyridinyl)methyl]-9-(1-methylethyl)- Featured

2670382-79-1
DC65028 4-(((1r,4r)-4-aminocyclohexyl)oxy)-2-chlorobenzonitrile hydrochloride Featured

1335049-54-1
DC65029 Vactosertib HCl Featured

Vactosertib Hydrochloride (EW-7197 Hydrochloride) is a small-molecule ATP-competitive inhibitor of TGFβRI (ALK5) with an IC50 of 12.9 nM.

1352610-25-3
DC65030 Benzoic acid, 2-(2,2,2-trifluoro-1-methylethyl)hydrazide Featured

1453473-00-1
DC65031 1-(1,1,1-trifluoropropan-2-yl)hydrazine Featured

118737-68-1
DC65032 (1S)-2,2,2-trifluoro-1-methylethyl]hrazine hydrocydhloride Featured

2764851-03-6
DC65033 Benzoic acid, 2-​[(1S)​-​2,​2,​2-​trifluoro-​1-​methylethyl]​hydrazide Featured

2642629-20-5
DC65034 7-Nitro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-tosyl-1H-indole Featured

2091135-03-2
DC65035 1H-Indole, 3-(2-chloro-5-fluoro-4-pyrimidinyl)-1-[(4-methylphenyl)sulfonyl]-7-nitro- Featured

2091135-05-4
DC65036 sodium 2-(4-methylpiperazin-1-yl)thiazole-5-carboxylate Featured

1542223-24-4
DC65037 2-AMINO-6-METHYL-N-O-TOLYLBENZAMIDE Featured

371244-06-3
DC65038 5-Pyrimidinecarbonitrile,6-[2-(dimethylamino)ethenyl]-1,4-dihydro-4-oxo-1-phenyl- Featured

103607-65-4
DC65039 Benzo[b][1,6]naphthyridine-4-carbonitrile, 3-chloro- Featured

104802-98-4
DC65040 CAL-130 Racemate Featured

CAL-130 Racemate is the racemate of CAL-130. CAL-130 Racemate is a PI3Kδ inhibitor.

474012-90-3
DC65041 Ethyl 5-(2,2-dimethyltetrahydro-2H-pyran-4-yl)-1H-indole-2-carboxylate Featured

2212021-76-4
DC65042 Methyl 3-(methoxymethyl)-1H-pyrazole-4-carboxylate Featured

318496-66-1
DC65043 [1(2H),2'-Bipyridin]-2-one, 3-amino- Featured

1797435-79-0
DC65044 Benzenemethanamine, 伪-(cyclopropylmethyl)-3-fluoro-4-methyl-, hydrochloride (1:1), (伪S)- Featured

2437236-67-2
DC65045 4H-1,3-Dioxolo[4,5-c]pyrrole-4-carboxylic acid, tetrahydro-2,2-dimethyl-6-oxo-, (3aS,4S,6aS)- Featured

1654009-11-6
DC65046 4-(2-(2-(1-methyl-1H-pyrazol-5-yl)-4-nitrophenoxy)ethyl)morpholine Featured

887938-10-5
DC65047 Morpholine, 4-[2-(2-bromo-4-nitrophenoxy)ethyl]- Featured

858679-56-8
DC65048 Temanogrel Featured

Temanogrel is a highly selective 5-HT2A receptor antagonist with a Ki of 4.9 nM.

887936-68-7
DC65049 5-Bromo-4-fluoro-1-methylindazole Featured

1784678-61-0
DC65050 CPD113920-P2 Featured

2375917-49-8
DC65051 2-Phenyl-1H-pyrrolo[2,3-b]pyridin-5-amine Featured

896116-37-3
DC65052 1H-Pyrrolo[2,3-b]pyridine, 5-nitro-2-phenyl- Featured

896114-91-3
DC65053 1,2-Hydrazinedicarboxylic acid, 1-(4-fluoro-3,5-dimethylphenyl)-, 1,2-bis(1,1-dimethylethyl) ester Featured

2212021-55-9
DC65054 (R)-1-(5-bromopyridin-2-yl)-2-(2,4-difluorophenyl)-1,1-difluoro-3-nitropropan-2-ol Featured

2089288-61-7
DC65055 Thiocyanic acid, 2-(2-chloro-4-methoxy-5-methylphenyl)-1-methyl-2-oxoethyl ester Featured

1253695-28-1
DC65056 di-tert-butyl (((4-methoxyphenyl)thio)carbonyl)-L-glutamate Featured

2321365-04-0
DC65057 INDEX NAME NOT YET ASSIGNED Featured

2583769-77-9
DC65058 Methyl 4-aminobicyclo[2.2.2]octane-1-carboxylate hydrochloride Featured

135908-43-9
DC60442 mPEG-CH2CH2CH2-NH2 Featured

DC65059 5-Methylsulfonyl-2-(2,2,2-trifluoro-1-Methylethoxy)benzoic acid Featured

845616-73-1
DC65060 5-Methylsulfonyl-2-(1,1,1-trifluoropropan-2-yloxy)benzoic acid Featured

845616-83-3
DC65061 ethyl 5-chloro-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxylate Featured

2359650-50-1
DC65062 BuChE-IN-TM-10 Featured

BuChE-IN-TM-10 (TM-10) is a potent butyrylcholinesterase (BuChE) inhibitor, with an IC50 of 8.9 nM.

2313524-95-5
DC65063 Zandatrigine Featured

Zandatrigine is a sodium channel protein type 8 subunit alpha (Scn8α) blocker.

2154406-04-7
DC65064 Benzoic acid, 4-[1-(1-methylethyl)-4-(trifluoromethyl)-1H-imidazol-2-yl]-, methyl ester Featured

2750602-57-2
DC65065 Benzoic acid, 4-[5-(trifluoromethyl)-1H-imidazol-2-yl]-, methyl ester Featured

2106447-92-9
DC65066 tert-butyl (1-(3-chloro-6-(3-cyano-2-hydroxyphenyl)quinolin-4-yl)piperidin-4-yl)carbamate Featured

2361216-97-7
DC65067 tert-butyl (1-(6-bromo-3-chloroquinolin-4-yl)piperidin-4-yl)carbamate Featured

2172875-14-6
DC65068 ethyl 2-(7-methoxy-3,4-dihydroisoquinolin-2(1H)-yl)-4-oxo-4,5-dihydrofuran-3-carboxylate Featured

1402060-22-3
DC65069 ethyl 4-oxo-2-((4-(2,2,2-trifluoroethyl)piperazin-1-yl)amino)-4,5-dihydrofuran-3-carboxylate Featured

1402060-26-7
DC65070 2H-1-Benzopyran-8-ol, 3-(4-morpholinylmethyl)- Featured

205242-46-2
DC65071 8-Hydroxy-2H-chromene-3-carbaldehyde Featured

923112-96-3
DC65072 Benzonitrile, 4-[(4-ethynylphenoxy)methyl]- Featured

2089320-09-0
DC65073 AZD9898 Featured

AZD9898 is an orally active leukotriene-C4 synthetase (LTC4S, glutathione S-transferase II) inhibitor, with an IC50 of 0.28 nM. AZD9898 mitigates the GABA binding and hepatic toxicity signal. AZD9898 has the potential to treat asthma.

2042347-69-1
DC65074 N-[[4-(2,2-dicyano-1-methoxy-vinyl)phenyl]methyl]-5-fluoro-2-methoxy-benzamide Featured

2764851-04-7
DC65075 AR antagonist 1 Featured

AR antagonist 1 (compound 29) is a potent androgen receptor (AR) antagonist and binds to E3 ligase ligands with weak binding affinities to VHL protein in the synthesis of PROTAC ARD-266.

1818885-54-9
DC65076 4,5-Dibromo-1-methyl-1H-1,2,3-triazole Featured

25537-64-8
DC65077 1H-1,2,3-Triazole, 4-bromo-1-methyl-5-[(phenylmethoxy)methyl]- Featured

2302095-32-3
DC65078 CPD100369-A6 Featured

298680-39-4
DC65079 (1r,3r)-3-amino-2,2,4,4-tetramethylcyclobutanol phosphorous acid Featured

1338812-52-4
DC65080 Oxotremorine M iodide Featured

Oxotremorine M iodide is a potent and selective muscarinic acetylcholine receptor (mAChR) agonist. Oxotremorine M iodide potentiates NMDA receptors by muscarinic receptor dependent and independent mechanisms.

3854-04-4
DC65081 9,10-dimethoxy-2-(2,4,6-trimethylanilino)-6,7-dihydropyrimido[6,1-a]isoquinolin-4-one Featured

76536-66-8
DC65082 Propanedioic acid, 2-phenyl-, 1-ethyl 3-[(3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl] ester Featured

113932-24-4
DC65083 6-iodo-2-methyl-3-((2-(1-methyl-1H-pyrazol-4-yl)pyridin-4-yl)oxy)pyridine Featured

2758900-45-5
DC65084 4-Fluoro-2-(1-methyl-1H-pyrazol-4-yl)pyridine Featured

1595860-49-3
DC65085 5-(5-((2-chloropyridin-4-yl)oxy)-6-methylpyridin-2-yl)-3-methyl-2-(methylthio)pyrimidin-4(3H)-one Featured

1628606-33-6
DC65086 AR antagonist 1 hydrochloride Featured

AR antagonist 1 (compound 29) hydrochloride is a potent androgen receptor (AR) antagonist and binds to E3 ligase ligands with weak binding affinities to VHL protein in the synthesis of PROTAC ARD-266 (HY-133020).

1818885-55-0
DC65087 cis-Tert-butyl 3-hydroxy-2,2,4,4-(tetramethyl)cyclobutylcarbamate Featured

1338812-41-1
DC65088 3-(3-(cyclopentyloxy)-4-methoxyphenyl)-3-(1,3-dioxoisoindolin-2-yl)propanoic acid Featured

192819-25-3
DC65089 CPD5077-G-A4-S Featured

2131091-23-9
DC65090 3-AMINO-3-(3-CYCLOPENTYLOXY-4-METHOXYPHENYL)PROPANOIC ACID Featured

192819-22-0
DC65091 2-methoxy-5-methyl-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)aniline Featured

1356963-01-3
DC65092 2(1H)-Quinoxalinone, 8-fluoro-7-(hydroxymethyl)-3-methyl- Featured

2756334-27-5
DC65093 2(1H)-Quinoxalinone, 7-bromo-8-fluoro-3-methyl- Featured

2756334-26-4
DC65094 2,6-dichloro-5-fluoro-N-((2-isopropyl-4-methylpyridin-3-yl)carbamoyl)nicotinamide Featured

2252403-81-7
DC65095 7-Chloro-6-fluoro-1-(2-isopropyl-4-methyl-3-pyridyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione Featured

2252403-82-8
DC65096 2-CHLORO-6-METHYLPYRIDINE-4-BORONIC ACID PINACOL ESTER Featured

697739-22-3
DC65097 4-Methoxytetrahydro-2H-pyran-4-carboxylic acid Featured

1010836-49-3
DC65098 (S)-5-(1-(pyrrolidin-3-yloxy)isoquinolin-3-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one Featured

1627603-89-7
DC65099 tert-butyl (S)-3-((3-cyanoisoquinolin-1-yl)oxy)pyrrolidine-1-carboxylate Featured

1627603-88-6
DC65100 tert-butyl (S)-3-((3-chloroisoquinolin-1-yl)oxy)pyrrolidine-1-carboxylate Featured

1627603-87-5
DC65101 1H-Indole-3-propanoic acid, 5,7-difluoro-2-(4-fluorophenyl)- Featured

2446818-55-7
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