DCC5067 |
Tcs-401 |
Insulin receptor sensitizing agent; Selective inhibitor of protein-tyrosine phosphatase 1B (PTP1B) |
|
DCC5068 |
Tc-t 6000 |
Potent equilibrative nucleoside transporter 4 (ENT4) inhibitor |
|
DCC5069 |
T-cupm |
Sorafenib analogue, retaining cytotoxicity similar to sorafenib in various human cancer cell lines and strongly inhibiting growth in the NCI-60 cell line panel |
|
DCC5070 |
Td-004 |
Novel degrader of the anaplastic lymphoma kinase (ALK) fusion protein, effectively inducing ALK degradation and inhibiting the growth of ALK fusion positive cell lines, SU-DHL-1 and H3122, significantly reducing the tumor growth in H3122 xenograft model |
|
DCC5071 |
Td-106 |
Novel IKZF1/3 degrader, inhibiting the proliferation of multiple myeloma cells in vitro as well as in vivo |
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DCC5072 |
Td-1211 |
Novel selective opioid receptor antagonist at all three receptor types |
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DCC5073 |
Td-428 |
Novel potent BET protein degrader, inhibiting cell proliferation due to suppressed C-MYC transcription |
|
DCC5074 |
Td-5471 Hydrochloride |
Novel long-acting β 2 -adrenoceptor agonist |
|
DCC5075 |
Tdcipp |
Hepatotoxicity inducer, significantly up-regulating the expression of genes involved in endoplasmic reticulum stress and Toll-like receptor (TLR) pathway |
|
DCC5076 |
Tdmq20 |
Novel Specific Copper Chelator, Reducing Memory Impairments in Alzheimer's Disease Mouse Models |
|
DCC5077 |
Tdp1-in-9a |
Novel potent inhibitor of tyrosyl-DNA phosphodiesterase 1 (Tdp1) |
|
DCC5078 |
Tdp222669 |
Novel inhibitor of the p53-Hdm2 protein-protein interaction, dose-dependently stabilized P53 and increased P21 and MDM2 expression in JAR choriocarcinoma cells, inducing the p53 regulated gene (PIG-3) and caspase activity |
|
DCC5079 |
Tdr32570 |
Novel antimalarial agent |
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DCC5080 |
Tecovirimat Hydrate
Featured
|
Novel inhibitor of viral p37, blocking the ability of virus particles to be released from infected cells, being used for the treatment of smallpox, monkeypox, orthopoxvirus, and orthopoxviral Disease. |
|
DCC5081 |
Tefinostat |
Novel monocyte/macrophage targeted histone deacetylase inhibitor |
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DCC5082 |
Teijin Compound 1 Hydrochloride
Featured
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CCR2 antagonist 4 hydrochloride (Teijin compound 1 hydrochloride) is a potent and specific CCR2 antagonist, with IC50s of 180 nM for CCR2b. CCR2 antagonist 4 hydrochloride potently inhibits MCP-1-induced chemotaxis with an IC50 of 24 nM. |
|
DCC5083 |
Teixobactin |
Natural antibacterial agent, being active against gram-positive bacteria. |
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DCC5084 |
Telenzepine |
Potent and selective M1 antimuscarinic |
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DCC5085 |
Telmesteine |
Mucolitic agent, inhibiting activation of nuclear factor kappa-κB (NF-κB) by blocking phosphoinositide 3-kinase/protein kinase B (PI3K/Akt)/IκB kinase (IKK) activities, showing the anti-inflammatory properties on inflammation-associated skin diseases |
|
DCC5086 |
Temoporfin |
Photosensitizing agent used in the treatment of squamous cell carcinoma of the head and neck, also showing activity agaimst COVID-19 Mpro |
|
DCC5087 |
Tenidap Sodium |
COX/5-LOX inhibitor and cytokine-modulating anti-inflammatory agent |
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DCC5088 |
Tertomotide |
Peptide vaccine, residues (611-626) of the human telomerase reverse transcriptase catalytic subunit (hTERT), for the treatment of solid cancers |
|
DCC5089 |
Terutroban Sodium |
Selective Thromboxane_receptor>thromboxane receptor antagonist |
|
DCC5090 |
Tet3.0 |
Mutually Orthogonal Bioorthogonal Amino Acid, Enabling Efficient Protein Dual-Labeling in Cells |
|
DCC5091 |
Tetrabenazine |
Reversible inhibitor of vesicular monoamine transporter 2, showing anti-chorea effect and decreasing uptake of monamines into synaptic vesicles, as well as depletion of monoamine storage |
|
DCC5092 |
Tetrabromobisphenol A |
Activator of the hepatic interferon pathway in rats |
|
DCC5093 |
Tetracenomycin X |
Potent inhibitor of protein synthesis, inhibiting translation by binding within the ribosomal exit tunnel |
|
DCC5094 |
Tetrazanbigen |
Inducer of S phase arrest and apoptosis in hepatocellular carcinoma QGY-7701 |
|
DCC5095 |
Texaline |
Antitubercular agent |
|
DCC5096 |
Texasin |
Potent and selective human leukocyte 5-lipoxygenase (5-LOX) inhibitor |
|