| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC22083 | DS-6930b | DS-6930b (DS-6930 calcium salt) is the calcium salt of DS-6930, which is a novel potent, selective PPARγ agonist with EC50 of 41 nM, Emax-68%. |
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| DC11177 | DS-70 | DS-70 (α4 integrin inhibitor DS-70) is a novel potent α/β- peptidomimetic antagonist of α4 integrin, binds to integrin α4β1 with nanomolar affinity. |
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| DC20976 | DS-7423 Featured | DS-7423 is a novel potent, small-molecule dual inhibitor of PI3K/mTOR with IC50 of 15.6, 1143, 249, 262 and 34.9 nM for PI3Kα, PI3Kβ, PI3Kγ, PI3Kδ, and mTOR respectively. |
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| DC11233 | DS-8500a | DS-8500a (DS8500a) is a novel potent, selective, orally available GPR119 agonist with EC50 of 51.5 nM in human GPR119-expressing CHO-K1 cells, displays no significant effect on 66 receptors, channels, or transporters. |
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| DC20973 | DS86760016 | DS86760016 is a novel selective bacterial leucyl-tRNA synthetase (LeuRS) inhibitor with IC50 of 0.38 uM (Escherichia coli, LeuRS). |
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| DC22081 | DS88790512 hydrochloride | DS88790512 is a potent, selective, and orally bioavailable blocker with IC50 of 11 nM, exhibits excellent selectivity against hERG and hNaV1.5 channels (IC50 >100 uM).. |
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| DC22080 | DS88790512 | DS88790512 is a potent, selective, and orally bioavailable blocker with IC50 of 11 nM, exhibits excellent selectivity against hERG and hNaV1.5 channels (IC50 >100 uM).. |
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| DC12193 | Ds-HAPP | Ds-HAPP is an anthrancenyl and dansyl fluorophore ligand. |
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| DC12643 | DSP-0565 | DSP-0565 (DSP0565) is a new drug candidate with broad anti-convulsant activity, does not bind to any GABA-A binding sites, may be caused as the result of its GABAergic function via novel target.. |
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| DC20977 | DSP-1053 | DSP-1053 is a novel potent serotonin reuptake (SERT) inhibitor with 5-HT1A partial agonistic activity that binds to human serotonin transporter and 5-HT1A receptor with Ki of 1.02 and 5.05 nM, respectively. |
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| DC20979 | DSP-6952 hydrobromide | DSP-6952 is a novel potent, selective, orally active 5-HT4 receptor partial agonist with Ki of 50-100 nM for human 5-HT4a/4b/4c. |
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| DC20980 | DT204 | DT204 (DT-204) is a novel SCFSkp2 inhibitor that reduces Skp2 binding to Cullin-1 and Commd1, synergistically enhances BTZ-induced apoptosis. |
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| DC20367 | dTRIM24 Featured | dTRIM24 is a potent TRIM24 bromodomain inhibitor with IC50 of 217.8 nM (TRIM24 ligand displacement). |
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| DC12473 | Dual BRM and BRG1 inhibitor 14 | Dual BRM and BRG1 inhibitor 14 is a potent, orally active inhibitor of Brahma Homolog (BRM)/SMARCA2 and Brahma-related gene 1 (BRG1) with IC50 of <5 nM for both. |
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| DC11175 | Dual DDR1 and DDR2 inhibitor 5n | Dual DDR1 and DDR2 inhibitor 5n is a highly potent, selective, dual Discoidin domain receptor DDR1 and DDR2 inhibitor with Kd of 7.9 and 8.0 nM, IC50 of 9.4 and 20.4 nM, repectively. |
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| DC3149 | Duloxetine hydrochloride | Duloxetine is a serotonin-norepinephrine reuptake inhibitor with Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD). |
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| DC12054 | Duocarmycin TM | Duocarmycin TM is an exceptionally potent antitumor antibiotic. |
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| DC20368 | Dynarrestin Featured | Dynarrestin is a novel inhibitor of cytoplasmic Dyneins 1 and 2, acts reversibly to inhibit cytoplasmic dynein 1-dependent microtubule binding and motility in vitro without affecting ATP hydrolysis. |
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| DC20905 | Dynein2-IN-37 | Dynein2-IN-37 (Ciliobrevin analog 37) is a potent, selective cytoplasmic dynein 2 ATPase activity antagonist with IC50 of 11 uM, shows weak inhibition for dynein 2 (IC50=280 uM). |
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| DC20369 | Dynole 34-2 | Dynole 34-2 is a potent dynamin GTPase inhibitor with IC50 of 6.9 and 14.2 uM for full-length dynI and dynII GTPase activity, respectively. |
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| DC10953 | DZ-2384 | DZ-2384 (DZ2384) is a microtubule-targeting agent, exhibits potent antitumor activity in models of multiple cancer types. |
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| DC20985 | E 6201 | E 6201 (E6201) is a potent, selective, dual MEK1 and MEKK1 inhibitor, inhibits LPS-induced TNFα transcription with IC50 of 50 nM. |
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| DC20986 | E 6446 Featured | E 6446 is a novel orally available small molecule inhibitor of TLR7 and TLR9 with IC50 of 1.78 uM and 0.01 uM, respectively. |
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| DC11213 | E1231 Featured | E1231 (E-1231) is a small molecule SIRT1 activator with EC50 of 0.83 uM, interactes with recombinant human SIRT1 protein and deacetylated liver X receptor-alpha (LXRα). |
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| DC20370 | E3 Ligand-Linker Conjugate 1 | E3 Ligand-Linker Conjugate 1 is an E3 ligand- Linker Conjugate for PROTAC. |
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| DC11570 | E3 Ligand-Linker Conjugate 5 | E3 Ligand-Linker Conjugate 5 is an E3 ligase ligand-linker conjugate for PROTAC.. |
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| DC12249 | E3 ligase Ligand 1 dihydrochloride | E3 ligase Ligand 1 dihydrochloride is a Hippel-Landau (VHL) E3 ligase-binding moiety based on PROTAC technology. |
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| DC11565 | E3 Ligase Ligand 2 Featured | E3 ligase Ligand 2 is a Ligand for E3 Ligase used in PROTAC technology. |
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| DC12092 | E3 Ligase Ligand-Linker Conjugates 23 TFA | E3 Ligase Ligand-Linker Conjugates 23 (TFA) is a synthesized compound that incorporates an E3 ligase ligand and a linker used in PROTAC technology. |
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| DC12181 | E3 Ligase Ligand-Linker Conjugates 25 Trifluoroacetate | E3 Ligase Ligand-Linker Conjugates 25 Trifluoroacetate is a synthesized compound that incorporates an E3 ligase ligand and a linker used in PROTAC technology. |
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