DC12208 |
Docosapentaenoic acid 22n-3 |
Docosapentaenoic acid (22n-3) is a component of phospholipids found in all animal cell membranes. |
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DC10247 |
Docusate Sodium |
Docusate Sodium is a laxative used to treat constipation, for constipation due to the use of opiates it maybe used with a stimulant laxative, can be taken by mouth or rectally. |
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DC12216 |
Dodecanoylcarnitine
Featured
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Dodecanoylcarnitine is present in fatty acid oxidation disorders such as long-chain acyl CoA dehydrogenase deficiency, carnitine palmitoyltransferase I/II deficiency, and is also associated with celiac disease. |
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DC9588 |
Dofequidar (fumarate) |
Dofequidar fumarate(MS-209 fumarate), an orally active quinoline compound, has been reported to overcome MDR by inhibiting ABCB1/P-gp, ABCC1/MDR-associated protein 1, or both.
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DC9323 |
Dalasetron (Mesylate hydrate) |
Dolasetron(MDL-73147) is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy. |
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DC3155 |
Donepezil hydrochloride
Featured
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Donepezil is a specific and potent AChE inhibitor for bAChE and hAChE with IC50 of 8.12 nM and 11.6 nM , respectively. |
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DC11103 |
Tavapadon
Featured
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Tavapadon is a potent, orally-bioavailable, selective partial agonist of the dopamine D1 and D5 receptors. |
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DC9308 |
Doravirine (MK-1439)
Featured
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Doravirine (MK-1439) is a non-nucleoside reverse transcriptase inhibitor. |
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DC20365 |
Dorrigocin A |
Dorrigocin A is a natural compound that shows potent antiproliferative effect on tumor cell line.. |
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DC4219 |
Dorzolomide hydrochloride |
Dorzolamide HCl is a carbonic anhydrase inhibitor. |
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DC20057 |
Dot1L-IN-1 |
Dot1L-IN-1 is a highly potent, selective and structurally novel Dot1L inhibitor with a Ki of 2 pM. |
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DC21895 |
DOTA-ADIBO |
DOTA-ADIBO is a Click Chemistry intermidate used for antibody-drug conjugates.. |
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DC10313 |
Dovitinib lactate |
Dovitinib(CHIR-258; TKI258) lactate is a potent inhibitor of fibroblast growth factor receptor 3 (FGFR3) with an IC50 of 5 nM. |
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DC9597 |
Doxapram (hydrochloride hydrate) |
Doxapram hydrochloride hydrate inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 410 nM, 37 μM, 9 μM, respectively.
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DC23775 |
DPA-714 |
DPA-714 is a potent, selective ligand for the translocator protein (TSPO) with Ki of 7.0 nM. |
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DC11173 |
DRAinh-A250
Featured
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DRAinh-A250 is a specific inhibitor of Cl-/anion exchanger SLC26A3 (DRA), fully and reversibly inhibits SLC26A3-mediated Cl- exchange with HCO3-, I-, and thiocyanate (SCN-) with IC50 of ~0.2 uM. |
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DC20366 |
DRAK2-IN-16 |
DRAK2-IN-116 is a potent, selective DRAK2 inhibitor with IC50 of 3 nM, shows weak inhibition for DRAK1 (IC50=51 nM) and no significant activity against DAPK1/2/3 (IC50>1 uM).. |
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DC20103 |
D-Ribose(mixture of isomers)
Featured
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D-Ribose(mixture of isomers) is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose(mixture of isomers) is active in protein glycation |
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DC20967 |
DRI-C21045 |
DRI-C21045 is a novel small-molecule inhibitor of CD40-CD40L protein-protein interaction with IC50 of 0.17 uM in cell-based assays. |
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DC10919 |
DRP1 inhibitor 4 |
DRP1 inhibitor 4 is a selective, small molecule inhibitor of the mammalian mitochondrial division dynamin, DRP1 with IC50 of 1.0 uM, shows no activity against OPA1 and DYN1 (IC50>100 uM).. |
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DC12598 |
DRV1 (GPR32) agonist C2A |
DRV1 (GPR32) agonist C2A (NCGC00135472) is a synthetic molecule that activate human resolvin D1 receptor DRV1/GPR32 receptor with EC50 of 0.37 uM and 0.05 uM in β-arrestin and cAMP assays, respectively. |
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DC20968 |
DS-1040 |
DS-1040 (DS1040) is a small molecule inhibitor of the activated thrombin-activatable fibrinolysis inhibitor (TAFIa) with IC50 of 1.7 ng/mL for rabbit TAFIa. |
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DC20969 |
DS-1040 tosylate |
DS-1040 tosylate (DS1040) is a small molecule inhibitor of the activated thrombin-activatable fibrinolysis inhibitor (TAFIa) with IC50 of 1.7 ng/mL for rabbit TAFIa. |
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DC20970 |
DS-1040 tosylate hydrate |
DS-1040 tosylate hydrate (DS1040) is a small molecule inhibitor of the activated thrombin-activatable fibrinolysis inhibitor (TAFIa) with IC50 of 1.7 ng/mL for rabbit TAFIa. |
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DC20974 |
DS16570511 |
DS16570511 is a cell-permeable inhibitor of the mitochondrial calcium uniporter (MCU) that inhibits serum-induced mitochondrial Ca2+ influx in HEK293A cells with IC50 of 7 uM. |
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DC20975 |
DS-2330
Featured
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DS-2330 is a phosphorous lowering agent for treating hyperphosphatemia in chronic kidney disease.. |
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DC20971 |
DS-2969b |
DS-2969b (DS 11960558) is a novel orally active GyrB inhibitor, inhibits the supercoiling activity of C. difficile DNA gyrase with IC50 of 20 ng/mL. |
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DC11726 |
Milademetan
Featured
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Milademetan (DS-3032) is a specific and orally active MDM2 inhibitor for the research of acute myeloid leukemia (AML) or solid tumors. Milademetan (DS-3032) induces G1 cell cycle arrest, senescence and apoptosis. |
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DC22082 |
DS-437
Featured
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DS-437 is a potent, selective, dual inhibitor of PRMT5 and PRMT7 with IC50 of 6.0 uM for both, DS-437 is inactive against 29 other human protein-, DNA-, and RNA-methyltransferases. |
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DC12411 |
DS-6930
Featured
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DS-6930 (DS 6930, DS6930) is a novel potent, selective PPARγ agonist with EC50 of 41 nM, Emax-68%; significantly recruits several cofactors, such as RIP140 and PGC1, in cofactor recruitment assays; demonstrateshigh PPARγ agonist potency with robust plasma glucose reduction, maintains diminished PPARγ-related adverse effects upon toxicological evaluation in vivo, and demonstrated no hepatotoxicity. |
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