Cat. No. | Product name | CAS No. |
DC11754 |
AD 2900
Featured
AD 2900 (AD2900, AD-2900) is a novel potent, broad S1P receptor antagonist with IC50 of 3.8, 3.2, 6.2, 5.9 and 0.405 uM for S1P1, 2, 3, 4 and 5 respectively. |
18360-29-7 |
DC10633 |
AD80
Featured
AD80, a multikinase inhibitor, shows strong activity against human RET, BRAF, S6K, and SRC but were much less active than either AD57 or AD58 against mTOR. The IC50 value for RET is 4 nM. |
1384071-99-1 |
DC20301 |
ADAMTS-5 inhibitor 15f
ADAMTS-5 inhibitor 15f is a highly potent and selective inhibitor of metalloprotease ADAMTS-5 with IC50 of 30 nM, >50-fold selectivity against ADAMTS-4 and >1000-fold selectivity against ADAMTS-1/13, MMP-13 and TACE. |
1394122-49-6 |
DC20302 |
ADAMTS-5 inhibitor 8
ADAMTS-5 inhibitor 8 is a highly potent and selective inhibitor of metalloprotease ADAMTS-5 with IC50 of 30 nM, >50-fold selectivity against ADAMTS-4 and >1000-fold selectivity against ADAMTS-1/13, MMP-13 and TACE. |
1394122-20-3 |
DC9362 |
Adarotene
Adarotene (ST1926) is an effective apoptosis inducer and surprisingly produced DNA damage.ST1926 exhibites a potent antiproliferative activity on a large panel of human tumor cells. IC50 value: 0.12 uM (LNCaP cell) [1] Target: Apoptosis inducer; Antican |
496868-77-0 |
DC20642 |
ADC-3680
ADC-3680 (PTR-36, ADC-3680B) is a potent, selective prostaglandin D2 receptor (DP2, CRTH2) antagonist for the treatment of asthma.. |
1263765-61-2 |
DC21294 |
MK-1029
ADC-3680 is a potent, selective prostaglandin D2 receptor (DP2, CRTH2) antagonist for the treatment of asthma.. |
1242273-04-6 |
DC4155 |
Adefovir Dipivoxil
Featured
Adefovir Dipivoxil(Preveon, Hepsera) works by blocking reverse transcriptase, an enzyme that is crucial for the hepatitis B virus (HBV) to reproduce in the body. |
142340-99-6 |
DC10244 |
Ademetionine disulfate tosylate
Ademetionine Disulfate Tosylate is the disulfate-tosylate mixed salt of a mixture of diastereoisomers of the ademetionine ions. Ademetionine possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. |
97540-22-2 |
DC20163 |
Adenosine 5'-monophosphate monohydrate; 5'-Adenylic acid;5'-AMP
Adenosine 5'-monophosphate monohydrate (5'-AMP) is an activator of a class of protein kinases known as AMP-activated protein kinase (AMPK). |
18422-05-4 |
DC20303 |
Adhesamine
Adhesamine is a diaryldispirotripiperazine derivative that selectively targets cell-surface glycosaminoglycans, especially heparan sulfate, for increasing cell adhesion and growth. |
462605-73-8 |
DC12091 |
AdipoRon hydrochloride
Featured
AdipoRon hydrochloride is an orally active and specific AdipoR agonist, binding to AdipoR1 and AdipoR2, with Kds of 1.8 and 3.1 μM, respectively. |
1781835-20-8 |
DC7050 |
ADL5859 HCl
Featured
ADL5859 agonizes δ-opioid receptor with a 1000-fold selectivity than µ- or κ-opioid receptor with Ki of 32 nM and 37 nM, respectively.ADL5859 displays weak inhibitory activity at the hERG channel with an IC50 of 78 μM. The EC50 of ADL5859 against δ opioid |
850173-95-4 |
DC20644 |
ADM 12
ADM 12 (ADM_12. |
1644134-60-0 |
DC9324 |
Adoprazine
Adoprazine, a potential atypical antipsychotic bearing potent D2 receptor antagonist and 5-HT1A receptor agonist properties. |
222551-17-9 |
DC12115 |
Adrenomedullin (AM) (1-52), human TFA (Human adrenomedullin-(1-52)-NH2 (TFA))
Adrenomedullin (AM) (1-52), human (TFA) affects cell proliferation and angiogenesis in cancer. |
|
DC20645 |
ADT-094
ADT-094 (ADT094) is a novel, non-COX inhibitory sulindac derivative that potently and selectivity inhibits colon tumor cell growth by inhibiting PDE5 and PDE10 with IC50 of 2.4 uM and 0.5 uM, respectively. |
|
DC11097 |
ADX-102 (Reproxalap;NS-2)
Featured
ADX-102 (Reproxalap, NS-2) is a novel small molecule immunomodulator that covalently binds aldehydes including malondialdehyde and 4-hydroxynonenal, which have been shown to mediate inflammatory pain; DX-102 is a promising agent for the treatment of dry eye disease. |
916056-79-6 |
DC5113 |
AEE-788 (NVP-AEE788)
Featured
AEE788 is a potent inhibitor of EGFR and HER2/ErbB2 with IC50 of 2 nM and 6 nM, less potent to VEGFR2/KDR, c-Abl, c-Src, and Flt-1, does not inhibit Ins-R, IGF-1R, PKCα and CDK1. Phase 1/2. |
497839-62-0 |
DC23140 |
AF38469
Featured
AF38469 is a potent, selective, orally bioavailable Sortilin inhibitor with IC50 of 330 nM, shows no activity against the NTR1 receptor as well as a panel of targets known to bind acidic molecules (δ-Opioid, GPR40, PPARδ, EP1, Angiotensin AT1, Endothelin |
1531634-31-7 |
DC12539 |
AF40431
AF40431 (AF-40431) is the first reported small-molecule ligand of the VPS10P family sorting receptor Sortilin with IC50 of 4.4 uM, binds in the neurotensin-binding site of sortilin.. |
181125-92-8 |
DC23642 |
AF-792
AF-792 (RO-5) is a novel selective P2X3 and P2X2/3 antagonist with pIC50 of 8.2 and 7.9 respectively, with no inhibition at other P2X receptors. |
927872-24-0 |