| DC10870 |
EMA400
Featured
|
EMA400 is a potent and highly selective AT2R antagonist. |
|
| DC7731 |
Emapunil(AC-5216)
Featured
|
Emapunil(AC-5216;XBD-173) is a translocator protein |
|
| DC7117 |
EMD534085 |
EMD534085 is a kinesin inhibitor currently in clinical development. |
|
| DC9620 |
EMD638683
Featured
|
EMD638683 is a potent SGK1 inhibitor with an IC50 of 3 uM. |
|
| DC8885 |
EMICORON
Featured
|
EMICORON is a novel G-quadruplex (G4) ligand showing high selectivity for G4 structures over the duplex DNA, causing telomere damage and inhibition of cell proliferation in transformed and tumor cells. |
|
| DC9771 |
ACU4429,ACU 4429,ACU-4429
Featured
|
Emixustat hydrochloride strongly inhibits 11-cis-retinol production with IC50 values of 232 ± 3 nM. |
|
| DC10314 |
Emixustat |
Emixustat, a novel visual cycle modulator, is an inhibitor of the visual cycle isomerase with an IC50 value of 4.4 nM in vitro. |
|
| DC22785 |
EML-405 |
EML-405 (EML405) is a small-molecule inhibitor of Spindlin1 (SPIN1) with Kd of 14 uM. |
|
| DC5018 |
Empagliflozin (BI-10773)
Featured
|
Empagliflozin is a potent, selective sodium glucose co-transporter-2 inhibitor that is in development for the treatment of type 2 diabetes. Empagliflozin is an inhibitor of the sodium glucose co-transporter-2 (SGLT-2), which is found almost exclusively in |
|
| DC23171 |
Empesertib(BAY 1161909)
Featured
|
Empesertib (BAY-1161909, BAY1161909) is a potent, selective Monopolar spindle 1 (Mps1/TTK) inhibitor with IC50 of 0.34 nM. |
|
| DC12273 |
EMT inhibitor-1 |
EMT inhibitor-1 is an inhibitor of of Hippo, TGF-β, and Wnt signaling pathways with antitumor activities. |
|
| DC23108 |
EN460
Featured
|
EN460 is a specific mall molecule inhibitor of endoplasmic reticulum oxidation 1 (ERO1), interacts selectively with the reduced, active form of ERO1α and prevents its reoxidation (IC50=1.9 uM). |
|
| DC24204 |
EN6
Featured
|
EN6 is a small-molecule in vivo activator of autophagy that covalently targets cysteine 277 in the ATP6V1A subunit of the lysosomal v-ATPase, which activates mTORC1 via the Rag guanosine triphosphatases. |
|
| DC20892 |
Enadoline |
Enadoline (CI 977. |
|
| DCAPI1334 |
Enalapril maleate (Vasotec) |
Enalapril maleate (Vasotec) |
|
| DC8403 |
Endoxifen (Z-isomer hydrochloride)
Featured
|
Endoxifen HCl, the active metabolite of Tamoxifen, ia a potent and selective estrogen receptor antagonist. Phase 2. |
|
| DC7589 |
Eniporide(EMD96785)
Featured
|
Eniporide is a The Na(+)/H(+) exchange inhibitor. |
|
| DC20993 |
ENMD-1068
Featured
|
ENMD-1068 is a novel selective PAR2 antagonist without inhibitory activity against thrombin-mediated PAR3 and PAR4 signaling. |
|
| DC9247 |
AP-III-a4 hydrochloride
Featured
|
ENOblock Hcl(AP-III-a4 Hcl) is a novel small molecule which is the first, nonsubstrate analogue that directly binds to enolase and inhibits its activity (IC50=0.576 uM); inhibit cancer cell metastasis in vivo. |
|
| DC7119 |
ENO block(AP-III-a4)
Featured
|
ENOblock(AP-III-a4) is a novel small molecule which is the first, nonsubstrate analogue that directly binds to enolase and inhibits its activity (IC50=0.576 uM); inhibit cancer cell metastasis in vivo. |
|
| DC8778 |
Enocitabine |
Enocitabine is an anti-tumor agent and an antineoplastic. A derivative of Cytarabine. |
|
| DC20018 |
Enocyanin
Featured
|
Enocyanin is an anthocyanin extracted from grapes. Enocyanin shows inhibitory effect on the leucine aminopeptidase, acid phosphatase, γ-glutamyl transpeptidase and esterase activity. |
|
| DC8321 |
Entacapone
Featured
|
Entacapone is a specific, potent, peripherally acting catechol-O-methyltransferase (COMT) inhibitor with IC50 of 151 nM for PD treatment. |
|
| DC4208 |
Entecavir Monohydrate
Featured
|
Entecavir hydrate belongs to the family of medicines called antivirals. |
|
| DC8881 |
Entecavir |
Entecavir is a deoxyguanosine nucleoside analogue with antiviral activity against the hepatitis B virus (HBV). |
|
| DC24202 |
Ent-kaurene
Featured
|
Ent-kaurene is a tetracyclic diterpene consisting of ent-kaurane, where the 6-methyl group is replaced by methylene. It derives from a hydride of an ent-kaurane. |
|
| DC21856 |
Enviroxime |
Enviroxime (Zinviroxime. |
|
| DC20848 |
Enzaplatovir |
Enzaplatovir (BTA-585, BTA-C585) is an orally bioavailable RSV fusion protein inhibitor for the treatment of respiratory syncytial virus infections.. |
|
| DC20950 |
EOAI3402143 |
EOAI3402143 (Deubiquitinase inhibitor G9, EOAI 3402143) is a novel covalent deubiquitinase Usp9x/Usp24 inhibitor with increased aqueous solubility and greater cellular Usp9x inhibitory activity than WP1130. |
|
| DC21601 |
Epertinib |
Epertinib (S-222611) is a novel potent, orally active, reversible EGFR and HER2 inhibitor with IC50 of 1.48, 7.15 and 2.49 nM for EGFR, HER2 and HER4, respectively. |
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