| DC20373 |
Epeleuton |
An anti-inflammation agent.. |
|
| DC24172 |
Oxaceprol |
An anti-inflammatory agent used in the treatment of osteoarthritis. |
|
| DC23252 |
GNF-Pf-5660 |
An antimalarial candidate that demonstrates potent blood-stage and transmission-blocking activity, shows potent ABS activity (IC50 <25 nM) against drug-sensitive 3D7 and multidrug-resistant Dd2 parasites. |
|
| DC25077 |
Naphthoquine phosphate
Featured
|
Naphthoquine phosphate is a potent and orally active antimalarial agent. Naphthoquine phosphate has thorough killing function for various schizonts of plasmodia, including resistance of P. falciparum to Chloroquine. |
|
| DC10594 |
Tolcide 2230
Featured
|
An antimicrobial agent used as a substitute for chlorophenols |
|
| DC22497 |
MMAF-OMe
Featured
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MMAF-Ome belongs to ADC, and inhibits several tumor cell lines with IC50s of 0.056 nM, 0.166 nM, 0.183 nM, and 0.449 nM for MDAMB435/5T4, MDAMB361DYT2, MDAMB468, and Raji (5T4-) cell lines, respectively. |
|
| DC22483 |
Quinacrine dihydrochloride |
An antiprotozoal, antirheumatic and intrapleural sclerosing agent. |
|
| DC22614 |
Risperidone hydrochloride |
An antipsychotic agent with serotonin-S2 and dopamine-D2 antagonistic properties. |
|
| DC22613 |
Risperidone mesylate |
An antipsychotic agent with serotonin-S2 and dopamine-D2 antagonistic properties. |
|
| DC24155 |
Suramin |
An antitrypansomal drug that also possesses antitumor activity. |
|
| DC22844 |
WIN 52084 |
An antiviral compound that inhibits attachment to cells, inhibits human rhinovirus type 14 (HRV14) replication.. |
|
| DC22869 |
E3 Ligand-Linker Conjugate 3(E3 Ligase Ligand-Linker Conjugates 19)
Featured
|
An E3 ligase ligand-linker conjugate for PROTAC. |
|
| DC26084 |
LE-135
Featured
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LE135 is a retinoid acid receptor antagonist, produces pain through direct activation of TRP channels. |
|
| DC22495 |
Lenampicillin hydrochloride |
An efficient prodrug of ampicillin with enhanced absorption and decreased side effects.. |
|
| DC24168 |
(R)-(-)-Ibuprofen
Featured
|
An enantiomer of Ibuprofen that is generally not considered a COX inhibitor and is instead thought to be involved in pathways of lipid metabolism as it is incorporated into triglycerides along with fatty acids. |
|
| DC22361 |
(S)-(+)-Ibuprofen |
An enantiomer of Ibuprofen that more potently inhibits COX activity, thromboxane formation, and platelet aggregation than the (R)-form. |
|
| DC24138 |
Synaptamide |
An endogenous DHA metabolite that promotes neurite growth, synaptogenesis, and synaptic function both in vitro and in vivo. |
|
| DC23324 |
C-1311 dihydrochloride |
An imidazoacridinone analogue with potent in vivo antitumour activity, inhibits the catalytic activity of Topoisomerase II. |
|
| DC25076 |
Imazamox |
An imidazolinone herbicide that effectively controls a broad spectrum of weed species.. |
|
| DC23914 |
Thymalfasin
Featured
|
An immunoactive peptide that has been shown to inhibit cell proliferation and induce apoptosis in human leukemia, non-small cell lung cancer, melanoma, and other human cancers. |
|
| DC22995 |
IRES-J007
Featured
|
IRES-J007 ia an improved IRES inhibitor that blocks IRES-hnRNP A1 binding; binds to a small pocket structure within the RRM-containing fragment of hnRNP A1 (UP1 fragment), inhibits cyclin D1 and c-MYC IRES activity to a greater extent compared with C11 (IRES-C11); significantly reduces tumor growth of GBM xenografts in mice, and markedly reduces the mRNA translational state of cyclin D1 and c-MYC transcripts combined with PP242. |
|
| DC22542 |
Roflumilast Impurity E |
An impurity of Roflumilast, which is a selective and long-acting inhibitor of PDE-4 with IC50 value of 0.8 nM.. |
|
| DC20988 |
Indirubin E804 |
An indirubin derivative that potently blocks constitutive STAT3 signaling in human breast and prostate cancer cells, directly inhibits Src kinase activity (IC50=0.43 uM) in vitro. |
|
| DC22998 |
MIND4-17 |
An inducer of NRF2 that selectively activates NRF2 signaling with CD value (The concentration that doubles the specific activity) of 0.18 uM. |
|
| DC23993 |
Aldose reductase-IN-1 |
An inhibitor of aldose reductase with IC50 of 28.9 pM. |
|
| DC22549 |
KDM5A-IN-1 |
An inhibitor of histone demethylase.. |
|
| DC23937 |
SIBA |
An inhibitor of the IMP-selective cytosolic 5'-nucleotidase (IC50=2-6 mM). |
|
| DC22360 |
Valifenalate |
An insecticide agent that is approved for application on high-value crops such as grapes, tomatoes and other vegetables.. |
|
| DC24195 |
Benoxafos |
An insecticide agent.. |
|
| DC24177 |
Mitiglinide calcium hydrate
Featured
|
An insulin secretion stimulator by closing the ATP-sensitive potassium KATP channels in pancreatic β cells. |
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