Novel antifungal and fungicidal agent

Quantity (mg or Unit) Unit Price ($/mg or $/Unit) Final Price 100 $13.95 Total: $1,395.00 50 $16.12 Total: $806.00 25 $18.91 Total: $472.75 10 $22.32 Total: $223.20 5 $26.35 Total: $131.75

Novel selective inhibitor of RARγ

Squalene synthase inhibitor

Retinoic acid receptor (RAR) pan-antagonist

Novel and selective neuropeptide Y1 receptor antagonist

Novel potent inhibitor of the ATP hydrolase activity of mitochondrial F1F0 ATP synthase

Potent and selective β3 full agonist

Potent and selective p56(lck) inhibitor

Selective ATP hydrolase inhibitor

Potent and selective beta-lactam tryptase inhibitor, inhibiting factor XIa and producing antithrombotic efficacy with minimal bleeding time prolongation

Highly potent and selective phosphodiesterase 5 (PDE 5) inhibitor

Novel fluoro-substituted camptothecin, inducing topoisomerase I-mediated DNA breaks

Novel dissociated glucocorticoid receptor modulator

Novel Selective CYP17A1 Lyase Inhibitor

Prodrug of the novel fluoro-substituted camptothecin analog, BMS-286309

Novel Inhibitor of human immunodeficiency virus type 1 (HIV-1) attachment

Potent and selective dipeptidyl peptidase IV (DPP-IV) inhibitor

Novel, potent, exceptionally selective inhibitor of TNF-α Converting Enzyme (TACE)

Novel Inhibitor of human immunodeficiency virus type 1 (HIV-1) attachment

Novel potent antagonist of corticotropin-releasing factor/hormone receptor 1 (CRHR-1)

Novel Novel γ-secretase modulator, decreasing Aß1-40 and Aß1-42 and increasing Aß1-37 and Aß1-38 in rat brain modulator, decreasing Aß1-40 and Aß1-42 and increasing Aß1-37 and Aß1-38 in rat brain

Novel potent antagonist of corticotropin-releasing factor/hormone receptor 1 (CRHR-1)

Novel potent antagonist of corticotropin-releasing factor/hormone receptor 1 (CRHR-1)

Potent, Orally Bioavailable, Metabolically Stable Thumb Site 1 Inhibitor of the Hepatitis C Virus NS5B RNA-Dependent, RNA Polymerase

Novel potent and selective P2Y1 purinergic receptor antagonist.

Novel inhibitor of the influenza nucleoprotein (INF-NP)

Potent alpha7 Nicotinic receptor partial agonist, improving cognition in preclinical rodent model

Potent and selective GPR119 agonist

Novel Agonist of Sphingosine-1-Phosphate (S1P1)

Selective RARγ agonist

Novel GPR119 agonist

Novel S1P1 receptor modulator

Novel γ-secretase modulator

Novel pan-genotype inhibitor of HCV NS5B polymerase via binding to the primer grip site

G-quadruplex ligand, decreasing oncogene expression

Novel fluorescent activity-based probe (ABP), being intrinsically dark and only emitting fluorescence after reaction with the target protease, are ideally suited for imaging techniques such as small animal noninvasive fluorescence imaging and live cell fl

Potent long-acting H2-receptor antagonist

Novel CD4 mimic, inhibiting HIV-1 entry into target cells with both significantly higher potency and neutralization breadth than previous congeners, while maintaining high selectivity for the target virus

Solvatochromic Nile Red Probe with FRET Quencher Reveal Lipid Order Heterogeneity in Living and Apoptotic Cells

Selective delta 1 opioid receptor antagonist

Inhibitor of topoisomerase I/II, inducing DNA cross-linking and significantly suppressing the growth of various NSCLC cell lines with or without mutations in epidermal growth factor receptor (EGFR)

Novel covalent substrate-competitive inactivator of AKT kinase

Novel Fluorescent, Highly Affine Histamine H3 Receptor Ligand

Fluorogenic dye for Live-Cell Fluorescence Microscopy

Novel fluorogenic dye for Live-Cell Fluorescence Microscopy

Natural inhibitor of protein tyrosine phosphatase 1B (PTP1B)

Potent Botulinum Neurotoxin A Light-Chain Inhibitor

Novel potent inhibitor of Botulinum neurotoxin/A light chain (BoNT/A LC)

Novel BOP-conjufated fluorescent dual α9β1/α4β1 integrin inhibitor

Novel. highly potent, selective, cell-permeable furin inhibitor, rescuing key features of cystic fibrosis airway disease

Proteolysis targeting chimeras (PROTAC), acting as a degrader of oncogenic BCR-ABL

Novel IKK-2 inhibitor, targeting the Ser177 and/or Ser181 residues in the kinase's activation loop domain.

Novel and highly potent histamine H3 receptor ligand

Potent and selective STAT5 inhibitor

Novel, Potential Dengue Virus NS2B/NS3 Protease Inhibitor

Histamine H3 receptor agonist prodrug

Novel modulator of TTD-PHD histone reader module, binding to the TTD groove, competing with linker binding and promoting open TTD-PHD conformations

Novel potent SQS inhibitor

Novel CrtM inhibitor

Squalene synthase (SQS) inhibitor, potently inhibiting CrtM

The first potent inhibitor of Burkholderia pseudomallei methionine aminopeptidase

Novel RBP4 antagonist with good in vitro potency and selectivity and optimal rodent pharmacokinetic (PK) and pharmacodynamic (PD) characteristics

Novel potent and selective dual FLT3/AURKA inhibitor

Potent direct PTEN inhibitor

Potent and se;rctive PTEN inhibitor, activating the insulin receptor kinase, inhibiting the dephosphorylation of autophosphorylated insulin receptors and epidermal growth factor receptors of rat liver endosomes

Novel apoptosis signal-regulating kinase 1 (ASK1) inhibitor with IC50 of 0.52μM in vitro in kinase assay

Novel potent inhibitor of human neutrophil activations

Quantity (mg or Unit) Unit Price ($/mg or $/Unit) Final Price 100 $292.50 Total: $29,250.00 50 $338.00 Total: $16,900.00 25 $396.50 Total: $9,912.50 10 $468.00 Total: $4,680.00 5 $552.50 Total: $2,762.50

Monoamine Reuptake Inhibitor

Inhibitor of cyclobrassinin hydrolase, a unique enzyme from the fungal pathogen Alternaria brassicicola

Natural small molecule isolated from dried heartwood of Caesalpinia sappan L, exhibiting multi-pharmacological activities

Novel multistage antimalarial inhibitor

Novel Inhibitor of Clostridium difficile

Novel potent inhibitor of spCas9, disrupting spCas9-DNA binding and exerting dose and temporal control of spCas9 in human cell lines

Novel HDAC inhibitor, inhibiting multiple HDAC enzymes and modulates acetylation levels in cells

Positive control for HSPC toxicity; Inhibitor of STK33

Negative control for tubastatin A

Novel inhibitor of parasite phenylalanyl-tRNA synthetase (PheRS)

Novel non-histone nuclear substrate of histone deacetylase 8 (HDAC8)

Novel selective BET BD1 inhibitor with preferred binding to of BRD4 BD1

Novel potent inhibitor of BRD4 BD2

Novel potent BRD4 D1 inhibitor with over 500-fold selectivity against BRD2 D1 and BRD4 D2 via ITC

Negative control in HDAC1/2/3/8 assays

Novel HDAC8 inhibitor

Novel Mitochondrial Content Inducer

Novel dihydroorotate dehydrogenase (DHODH) inhibitor

Novel multistage antimalarial inhibitor for single-dose treatment of malaria in mouse models

Novel specific inhibitor of the hypomorph growth

Novel inhibitor of dihydroorotate dehydrogenase (DHODH), showing in vitro activity against multidrug-resistant blood-stage parasites

Novel specific inhibitor of the hypomorph growth of EfpA, a largely uncharacterized, but essential efflux pump in Mtb

Novel water-soluble, DNA-binding photosensitizer for the eradication of both Gram-negative and Gram-positive bacteria

Active-site-directed inactivator of bacterial beta-lactamases

Highly κ/μ-selective potent κ ligand

Reversible inhibitor of monoamine oxidase A, acting on epinephrine, norepinephrine, serotonin, and dopamine

Inhibitor of the reuptake of both dopamine and serotonin in the brain

Mucolytic agent used in the treatment of respiratory disorders associated with viscid or excessive mucus.

Antitumor agent

Novel PTP1B inhibitor

Novel Ca V channels blocker, binding in the central cavity of the pore on the intracellular side of the selectivity filter, physically blocking the ion-conducting pathway

Protein kinase C (PKC) activator

Novel proteasome inhibitor, protecting against cerebral ischaemia through HIF1A accumulation and enhanced angioneurogenesis

Fluorescent probe in vitro and in vivo aiming at a tau-based diagnosis of Alzheimer's disease

Fluorescent probe, binding to neurofibrillary tangles with high contrast and selectivity over amyloid

Fluorescent probe visualizing neurofibrillary tangles in Alzheimer's disease

Novel potent covalent inhibitor of gut bacterial bile salt hydrolases (BSH)

Novel potent inhibitor of both HIV-1 and HIV-2 replication, being also active against the erythrocytic stages of P. falciparum

Novel respiratory syncytial virus (RSV) fusion inhibitor

Novel cell-permeable modulator of cellular morphogenesis in yeast and mammalian cells; Inhibitor of SARS-CoV Mpro activity via intensive H-bond network and hydrophobic interactions

Novel cell-permeable modulator of cellular morphogenesis in yeast and mammalian cells

Novel activator of PC1/3 and inhibitor of PC2

Novel activator of BtGH84, the first experimentally discovered small molecule activator of a glycoside hydrolase

Novel selective and potent competitive inverse agonist of human GPR43

Novel potent and selective covalent inhibitor of Bruton’s tyrosine kinase (BTK), targeting a noncatalytic cysteine residue (Cys481) for covalent bond formation

Novel potent inhibitor of Bruton’s tyrosine kinase (BTK)

The first small-molecule inhibitor with significant selectivity among the KCa2 channel subtypes

Novel inhibitor of alpha2beta1 integrin, decreasing average platelet adhesion in individuals with the C/T807T genotype but not in those harboring C807C

Novel unique Na V modulator, acting as a conspicuous outlier, eliminating fast but not slow inactivation

Novel effective reversible and noncovalent inhibitor of DprE1.

Negative control for BTZO-1

Ligand of the Imidazoline(2) binding site (I 2 BS), showing very good affinity for the I 2 BS (K i of 1.4 nM; K d = 1.3 nM), good selectivity compared with the α 2 -adrenoceptor (909-fold)

Potent and selective agonist of μ-opioid receptor (MOR) with relatively low affinity for the δ-opioid receptor and the κ-opioid receptor

Direct-acting vasodilator with anti-tachycardiac effect

Bulgecin A is an inhibitor of binuclear metallo-beta-lactamases and Lytic transglycosolase.

Potent inducer of anemia

Natural inhibitor of microRNA-21, reducing growth of cancer cells

Novel 11β-HSD1 inhibitor

Selective 11beta-hydroxysteroid dehydrogenase type 1 (11betaHSD1) inhibitor

Novel BB2 receptor antagonist. attenuating the feeding responses evoked by exogenous gastrin releasing peptide-29

Highly selective inhibitor of AChE

Novel Gemini vitamin D analog, targeting CD44-STAT3 signaling and inhibiting breast cancer invasion

Novel promising spectroscopic probe for inositol 5-phosphatase(s)

Novel potent and selective PTP-1B inhibitor

β-Hairpin Octapeptide, acting as a potent mouse melanocortin-4 receptor (mMC4R) antagonist

Natural inhibitor of BACE1

Novel sensitizer of BRAF wild-type melanoma cells to vemurafenib, significantly reducing melanoma cell viability, with limited toxicity for normal human fibroblasts

Novel broad-spectrum intracellular targeting antibacterial agent, interacting with the 70S ribosome of E. coli and inhibiting its protein synthesis, demonstrating superior clearance of bacteria from the spleen, liver, and kidneys of mice, infected with S.

Novel broad-spectrum intracellular targeting antibacterial agent, interacting with the 70S ribosome of E. coli and inhibiting its protein synthesis, demonstrating superior clearance of bacteria from the spleen, liver, and kidneys of mice, infected with S.

FPP analogue, bearing an alkyne group to allow for post-prenylation protein labeling

Novel multi-functional resveratrol derivative for the treatment of atrial fibrillation

Novel selective activator for TREK, against other two-pore domain K (K2P) channels

First-In-Class Inhibitor of the Interaction between Bacterial RNA Polymerase and Sigma Initiation Factor, Affecting the Viability and Toxin Release of Streptococcus pneumoniae

The first C3b-binding complement inhibitor, inhibiting the formation of the membrane attack complex (MAC) by preventing cleavage of C5

Inducer of mast cell degranulation

Novel potent inhibitor of botulinum neurotoxin serotype E (BoNT/E)

Novel covalent cross-linker to the SARS-CoV-2 frameshifting element (FSE), directly targeting engagement of the SARS-CoV-2 FSE in cells, dose dependently reducing frameshifting in cells expressing the SARS-CoV-2 FSE, with no significant effect on frameshi

Selective inhibitor of hCA IX and hCA XII

Potent and selective inhibitor of cathepsin B

Novel specific inhibitor of cathepsin L, effectively inhibiting degradation of LC3-II and GABARAP

Novel selective CaBdf1 BD1 inhibitor

Novel inhibitor of CaBdf1 BD1 with low-micromolar affinity and three- to fivefold selectivity relative to human Brd4 BD1

Novel selective CaBdf1 BD2 inhibitor

Potent, selective class B inhibitor of calcium-activated chloride channels (CaCCs)

Novel photocaged ERK1/2 inhibitor as a light-controlled anticancer agent

Potent agonist at thyroid hormone receptor (TR)

Effective inhibitor of the carbonic anhydrase (CA) from Trypanosoma cruzi (TcCA)

Novel inhibitor of p110

Cell permeable derivative of calcein, becoming fluorescent on hydrolysis

Dual inhibitor of fibroblast growth factors (FGF) and vascular endothelial growth factor (VEGF) ; Anti-angiogenic

Ionophore highly selective for Ca , potentiating responses to NMDA but not quisqualate

Transmembrane protease serine 2 (TMPRSS2) inhibitor for the treatment of chronic pancreatitis and postoperative gastric reflux, blocking SARS-CoV-2 replication in TMPRSS2-expressing human cells

Novel destabilizer of CAND1-Cullin1 interaction, inducing a p53-stress response pathway

Natural cannabinoid precursor

Natural cannabinoid precursor

Novel self-assembling lysine-rich cationic amphipathic peptide (CAP)

Reverse-transcriptase_inhibitor>Non-nucleoside reverse transcriptase inhibitor

Broad spectrum antibiotic used in the therapy of drug resistant tuberculosis as a second line agent

Antimuscarinic and anticholinergic, acting as an antagonist of NMDA receptor

Antioxidant, free radical scavenger and potent inhibitor of lipid peroxidation

Mixture of Meropenem and vaborbactam for adults with complicated urinary tract infections (cUTI), including a type of kidney infection, pyelonephritis, caused by specific bacteria

Analog of etomidate that interacts weakly with 11β-hydroxylase

Novel fluorescent probe targeting of G-quadruplex structures and trapping cytoplasmic RNA G-quadruplex structures in cells

Inducer of deformation in Zebrafish>Zebrafish through the AhR-mediated, CYP1A-independent pathway

Novel inhibitor of full-length GST-tagged CARM-1

Novel potent inhibitor of coactivator-associated arginine methyltransferase 1 (CARM1)

Novel, potent, long-acting, selective, orally bioavailable inhibitor of dipeptidyl peptidase 4 (DPP-4) with hypoglycemic activity

Anthracycline antineoplastic antibiotic, intercalating into DNA and interacting with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis.

Long acting ß2-adrenoreceptor agonist (LABA)

Novel orally available α4 integrin receptor inhibitor

Irreversible and nonselective Monoamine_oxidase_inhibitor>monoamine oxidase inhibitor (MAOI)

DNA minor groove alkylating agent, alkylating N3 of adenine in a consensus sequence 5'-(A/T)(A/T)A*

Novel Cas9 Inhibitor, direct binding to apo-Cas9, preventing Cas9:gRNA complex formation

The first inhibitor of fungal (1→3)-β-D-glucan synthesis

Natural potent neutrophil elastase (NE) inhibitor with an IC 50 value of 2.79 ± 0.07 μM

Novel activator of autophagy for potential treatment of cystic fibrosis

Selective inhibitor of cathepsin B endopeptidase and exopeptidase activities

Selective inhibitor of cathepsin B endopeptidase and exopeptidase activities

Novel selective reversible inhibitor of cathepsin X

Novel ligand of voltage-gated calcium channel α2δ-1 subunit (Cavα2δ-1)

Selective inhibitor of 15-hydroxy PGDH, significantly suppressing endogenous 11-oxo-ETE production with a corresponding increase in 11(R)-HETE

Isoform-selective inhibitor of histone deacetylase (HDAC1)

Novel potent CysLT2 receptor antagonist

Novel Mdm2 inhibitor, an analog of Nutlin-3

Novel Mdm2 inhibitor, an analog of Nutlin-3

Novel RAF kinase inhibitor

Novel SRC kinase inhibitor

Novel IκB kinase inhibitor

Novel Thymidine kinase (TK) inhibitor

Novel Cyclin-dependent kinase inhibitor

Novel IκB kinase inhibitor