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Cat. No. Product name CAS No.
DC23078 Biperiden Featured

Biperiden (KL 373) is a centrally-acting antiparkinsonian agent that functions as a selective central M1 cholinoreceptors blocker..

514-65-8
DC25079 Biperiden hydrochloride Featured

Biperiden Hcl (NSC 170950, NSC 84989) is a centrally-acting antiparkinsonian agent that functions as a selective central M1 cholinoreceptors blocker..

1235-82-1
DC5023 Birinapant (TL32711) Featured

Birinapant (TL32711) is a SMAC mimetic antagonist, mostly to cIAP1 with Kd of <1 nM, less potent to XIAP.

1260251-31-7
DC10863 Bis(tributylammonium) difluoromethylenediphosphonate Featured

Bis(tributylammonium) difluoromethylenediphosphonate

81336-71-2
DC10504 BISF-3 Featured

BISF CAS 118511-97-0

118511-97-0
DC20798 Bisperoxovanadium

Bisperoxovanadium (bpV(phen) potassium hydrate) is a bisperoxovanadium (bpV) compound which inhibits several different protein tyrosine phosphatases (PTPs), with selectivity for PTEN (IC50 =38 nM), also inhibits the vascular endothelial PTP, PTP-β (IC50=3

171202-16-7
DC20212 Bisphenol A

Bisphenol A is a starting material for the synthesis of plastics, primarily certain polycarbonates and epoxy resins, as well as some polysulfones and certain niche materials. It exhibits estrogen-mimicking, hormone-like properties.

80-05-7
DC21599 Bis-T-23

Bis-T-23 is a small molecule that stimulates actin-dependent dynamin oligomerization and promotes dynamin GTPase activity, increases actin polymerization in injured podocytes.

171674-76-3
DC11307 Bitertanol

Bitertanol is a broad-spectrum triazole fungicide that is active against a variety of fungi, including V. inaequalis and V. pirina.

55179-31-2
DC9616 BIX 02565 Featured

BIX 02565 is a novel ribosomal S6 kinase 2 (RSK2) inhibitor with an IC50 of 1.1 nM.

1311367-27-7
DC23383 Bizine

Bizine is a phenelzine analog that inhibits LSD1 with Ki of 59 nM, displays 23-fold, 63-fold, and >100-fold selectivity for LSD-1 over MAOA, MAOB, and LSD2 respectively.

1591932-50-1
DC20739 BJE6-106

BJE6-106 (B106) is a potent, selective PKCδ inhibitor with IC50 of 50 nM, displays excellent selectivity over classical PKC isozymes (a 1,000-fold PKCδ selectivity over PKCα).

1564249-38-2
DC22637 BKI1369 Featured

BKI-1369 is a bumped kinase inhibitor (BKI). BKI-1369 increases human Ether-a-go-go-related gene (hERG)-inhibitory activity with an IC50 of 1.52 μM. BKI-1369 reduces the parasite burden and diseases severity in the gnotobiotic pig model. BKI-1369 has been well characterized for potency, stability, metabolism, toxicity, pharmacokinetics and is potent against C. parvum in infected mice and calves.

1951431-22-3
DC23439 BL-1020

BL-1020 is an ester of GABA and perphenazine, fuctions as orally-active antipsychotic agent and acts as a D2 antagonist and GABA agonist.

503537-33-5
DC20800 BL-918 Featured

BL-918 is a small molecule activator of ULK1 with EC50 of 24 nM (243% kinase activity at 100 nM), induces autophagy via the ULK complex in SH-SY5Y cells.

2101517-69-3
DC12391 BL-AD008 Featured

BL-AD008 (BL-AD 008) is a novel small molecule, dual-target activator targeting AMPK/ZIPK; demonstrates remarkable anti-proliferative activities toward cervical cancer cells and could induce apoptosis by death-receptor and mitochondrial pathways; also sho

DC20107 Blasticidin S hydrochloride

Blasticidin S hydrochloride is a nucleoside antibiotic isolated from Streptomyces griseochromogenes. Blasticidin S is a potent inhibitor of protein synthesis in both prokaryotic and eukaryotic cells.

3513-03-9
DC20801 BLT-1 Featured

BLT-1 is an irreversible Scavenger receptor class B member I (SR-BI) inhibitor that blocks SR-BI-mediated selective lipid uptake and bidirectional cholesterol flux with an IC50 of 50 nM; significantly inhibits baicalin-induced cholesterol efflux in THP-1 macrophages.

321673-30-7
DC12650 BLU-667 trans form

BLU-667 trans form is the trans form of BLU-667, which is a highly potent, selective, next generation RET inhibitor..

2097132-93-7
DC11152 BLU-782 Featured

BLU-782 (BLU782) is a novel potent, selective inhibitor of Activin receptor-like kinase (ALK2) mutant R206H with binding IC50 of <10 Nm.

2141955-96-4
DC23305 BM-1197

BM-1197 is a potent, specific dual inhibitor of Bcl-2 and Bcl-xL with Ki of <1 nM, shows >1,000-fold selectivity over Mcl-1.

1391107-89-3
DC20802 BM-635

BM-635 is a small molecule anti-mycobacterial compound acting by inhibiting the mycobacterial membrane protein Large 3 (MmpL3).

1073372-01-6
DC23304 BM-957

BM-957 is a highly potent, dual Bcl-2 and Bcl-xL inhibitor with Ki of <1 nM for both, IC50 of 5.4 and 6.0 nM, respectively.

1391107-54-2
DC8270 BML-277 Featured

BML-277 (C 3742) is a selective Chk2 (checkpoint kinase 2) inhibitor with an IC50 of 15 nM.

516480-79-8
DC20321 Bm-MPK1-IN-15b

Bm-MPK1-IN-15b is a potent, orally bioavailable inhibitor of B. malayi stress-activated kinase Bm-MPK1 with IC50 of 24 nM.

2222294-62-2
DC23833 SB 4 (Eticovo) Featured

BMP signaling agonist sb4 is a small molecule BMP signaling agonist with EC50 of 73.6 nM, enhances the efficacy of BMPs and activates endogenous BMP4 target genes.

100874-08-6
DC20812 BMS 695735

BMS 695735 is a potent, selective IGF-1R inhibitor with IC50 of 34 nM.

1054315-48-8
DC22988 BMS-189453 Featured

BMS-189453 (BMS189453, BMS453) is a synthetic retinoid that acts as an agonist of RARβ and an antagonist of RARα and RARγ.

166977-43-1
DC22032 BMS-211

BMS-211 is a prodrug of the parent pan-CK2 inhibitor BMS-699..

DC11294 BMS-212

BMS-212 is a potent and selective stimulator of glucokinase (GK) (EC50 = 35 nM) that is promisingly used as an antidiabetic.

2173153-38-1
DC10200 BMS-214662

BMS-214662 is a potent and selective farnesyl transferase inhibitor with potent antitumor activity with an IC50 of 1.35 nM.

195987-41-8
DC7375 BMS-303141 Featured

BMS-303141 is a potent ATP-citrate lyase (ACL) inhibitor with IC50 value of 0.13 uM (human recombinant ACL).

943962-47-8
DC20808 BMS-394136

BMS-394136 is a potent, selective IKur/Kv1.5inhibitor, increases atrial action potential duration (APD) and prolongs AERP but not VERP in both rabbits and beagles..

343246-73-1
DC20809 BMS433771

BMS433771 is a potent, orally active RSV fusion inhibitor, exhibits excellent potency against multiple laboratory and clinical isolates of both group A and B viruses with mean EC50 of 20 nM.

543700-68-1
DC23529 BMS-457

BMS-457 is a potent and selective CCR1 antagonist with binding IC50 of 0.8 nM, >1,000-fold selectivity against other CC family receptors.

946594-19-0
DC23167 BMS-564929

BMS-564929 is a potent, selective androgen receptor modulator (SARM) that binds to AR with Ki of 2.11 nM.

627530-84-1
DC7897 BMS-582949 HCl Featured

BMS-582949 is a dual action p38 Kinase Inhibitor.

623152-17-0
DC22033 BMS-595

BMS-595 (BMS595) is a novel potent, selective, ATP-competitive casein kinase 2 (CK2) inhibitor with IC50 of 1.3 nM (CKα).

DC24131 BMS-599626 hydrochloride

BMS-599626 (AC-480) is a potent, selective inhibitor of EGFR and HER2 with IC50 of 20 nM and 30 nM.

873837-23-1
DC7730 Temsavir(BMS-626529) Featured

BMS-626529 is a novel small-molecule attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4+ T-cells.

701213-36-7
DC20805 BMS-641988

BMS-641988 is a potent, selective, nonsteroidal androgen receptor antagonist with Ki of 1.7 nM, MDA-MB-453 cell IC50 of 16 nM.

573738-99-5
DC20811 BMS-654457

BMS-654457 is a potent, reversible and direct inhibitor of factor XIa (FXa) with Ki of 0.4 nM.

1004551-41-0
DC22034 BMS-699

BMS-699 (BMS699) is a novel potent, selective, ATP-competitive casein kinase 2 (CK2) inhibitor with IC50 of 0.1 nM (CKα).

DC23482 BMS-741672

BMS-741672 is a potent, selective CCR2 antagonist for the treatment of neuropathic pain..

1004757-96-3
DC20813 BMS-751324

BMS-751324 is a novel clinical prodrug of BMS-582949, which is a highly selective p38α MAPK inhibitor with IC50 of 13 nM.

948842-66-8
DC20814 BMS-795311

BMS-795311 is a potent and orally available CETP inhibitor with IC50 of 3.8 nM, inhibits cholesteryl ester (CE) transfer with IC50 of 0.22 uM.

939390-99-5
DC7089 BMS-806 (BMS 378806)

BMS-806 (BMS 378806) is a small molecule gp120/CD4 inhibitor with an IC50 of median 5 nM.

357263-13-9
DC10494 BMS813160 Featured

BMS-813160 is a dual CCR2/CCR5 chemokine antagonist.

1286279-29-5
DC12670 BMS-817378 free base Featured

BMS-817378 is a prodrug of the dual Met/VEGFR-2 inhibitor BMS-794833.

1174161-69-3
DC23526 BMS-817399

BMS-817399 is a potent, selective, orally bioavailable CCR1 antagonist with binding IC50 of 1 nM, inhibits MIP-1α-induced chemotaxis with IC50 of 6 nM.

1202400-18-7
DC12635 BMS-818251

BMS-818251 (BMS818251) is a novel potent, small-molecule inhibitor of HIV-1 entry with EC50 of 0.019 nM against e laboratory-adapted HIV-1 strain NL4-3.

DC20815 BMS-823778 Featured

BMS-823778 (BMS823778) is an orally available, potent and selective inhibitor of 11βHSD-1 with IC50 of 2.3 nM, displays >10,000-fold selectivity over 11βHSD-2.

1140898-87-8
DC12512 BMS-823778 free base

BMS-823778 (BMS823778) is an orally available, potent and selective inhibitor of 11βHSD-1 with IC50 of 2.3 nM, displays >10,000-fold selectivity over 11βHSD-2.

1140897-32-0
DC7090 BMS-863233 (XL-413) Featured

BMS-863233, also known as XL-413, is an orally bioavailable cell division cycle 7 homolog (CDC7) kinase inhibitor with potential antineoplastic activity.

1169562-71-3
DC23891 BMS-869780

BMS-869780 is a potent γ-secretase modulator (GSM) that decreases Aβ1-42 (IC50=5.1 nM) and Aβ1-40 (IC50=25.1 nM) and increases Aβ1-37 and Aβ1-38 without inhibiting overall levels of Aβ peptides or other APP processing intermediates.

1235493-78-3
DC20817 BMS-871

BMS-871 is a potent, orally active pan-Notch inhibitor with IC50 of 4/1/4/3 nM for Notch1/2/3/4, respectively.

1584631-89-9
DC20818 BMS-884775

BMS-884775 is a potent, selective P2Y1 antagonist with IC50 of 0.12 nM.

1557206-59-3
DC11990 BMS-901715

BMS-901715 is a potent, selective adapter protein-2 associated kinase 1 (AAK1) inhibitor..

1699861-37-4
DC20819 BMS-919373

BMS-919373 is a potent I(Kur)/Kv1.5 channel blocker with IC50 of 50 nM, with selectivity versus hERG, Na, Ca channels and reduced the level of brain penetration.

1272353-82-8
DC23872 BMS-932481(BMS932481;BMS 932481) Featured

BMS-932481 (BMS932481) is a potent, selective, orraly active γ-secretase modulator (GSM), shows selectivity for Aβ40 and Aβ42 reduction (IC50=6.6 nM) while sparing total Aβ levels both in vitro and in vivo.

1263871-36-8
DC22445 BMS-933043

BMS-933043 is a novel highly selective, potent α7 nAChR partial agonist with binding Ki of 3.3 and 8.1 nM for rat and human α7, respectively.

1221973-93-8
DC23411 BMS-952048(BMS952048;BMS 952048)

BMS-952048 is a positive allosteric modulator of mGluR5 with EC50 of 10 nM..

1375751-32-8
DC21092 BMS-955176 Featured

BMS-955176 (GSK-3532795) is a second-generation HIV-1 maturation inhibitor that exhibits potent activity (EC50=3.9±3.4 nM) against a library (n=87) of gag/pr recombinant viruses.

1392312-45-6
DC20820 BMS-961955

BMS-961955 is an potent, allosteric inhibitor of HCV NS5B polymerase with EC50 of 7.9/4.3 nM for GT 1b/1a replicon respectively.

1431328-92-5
DC20821 BMS-962212 Featured

BMS-962212 is a potent, highly selective and reversible small molecule coagulation Factor XIa (FXIa) inhibitor with Ki of 0.7 nM.

1430114-34-3
DC23143 BMS-983970

BMS-983970 (BMS983970) is a potent, orally active, pan-Notch inhibitor, demonstrates robust anti-tumor activity at tolerated doses in multiple tumor xenograft models..

1584713-87-0
DC22035 BMS-984923

BMS-984923 (BMS-984923) is a potent silent allosteric modulator (SAM) of mGluR5 with competitive antagonism of MPEPy binding with Ki of 0.6 nM, but has no detectable agonist and antagonist activity at mGluR5 signaling.

1375755-46-6
DC23873 BMS-986115

BMS-986115 is an orally bioavailable, γ-secretase and pan-Notch inhibitor with potential antineoplastic activity.

1584647-27-7
DC23459 BMS-986118

BMS-986118 is a potent and selective GPR40 agonist with EC50 of 70 and 63 nM for hGPR40 and mGPR40, shows no PPARγ activity (EC50>47 uM).

1610562-74-7
DC26073 BMS-986122 Featured

BMS-986122 is a potent positive allosteric modulator of μ-opioid receptor, significantly increases the inhibition of forskolin-stimulated adenylyl cyclase activity produced by an EC10 (30 pM) concentration of endomorphin-I in CHO-μ cells..

313669-88-4
DC23609 BMS-986163

BMS-986163 is a water-soluble phosphate prodrug of BMS-986169, which is a novel GluN2B negative allosteric modulator (Ki=4.0 nM)..

1801151-09-6
DC12174 Deucravacitinib(BMS986165) Featured

BMS-986165 is a selective, potent, allosteric inhibitor of tyrosine kinase 2 (Tyk2).

1609392-27-9
DC23532 BMS-986166 Featured

BMS-986166 (BMS986166) is a potent, selective S1P receptor modulator for the treatment of ulcerative colitis..

1883345-06-9
DC23639 BMS-986169

BMS-986169 is a novel GluN2B negative allosteric modulator, demonstrates high binding affinity for the GluN2B allosteric site (Ki=4.0 nM) and selective inhibition of GluN2B receptor function (IC50=24 nM) in cells.

1801151-08-5
DC23460 BMS986187 Featured

BMS-986187 is a novel potent, positive allosteric modulator of δ-opioid receptor with EC50 of 30 nM, 100-fold selectivity over μ-opioid receptor..

684238-37-7
DC22036 BMT-046091

BMT-046091 (BMT046091) is a potent and selective AAK1 inhibitor with IC50 of 2.8 nM.

1551401-20-7
DC11989 BMT-090605

BMT-090605 (BMT 090605, BMT090605) is a potent, selective adapter protein-2 associated kinase 1 (AAK1) inhibitor with IC50 0.6 nM.

1551403-51-0
DC23998 BMX-IN-1 Featured

BMX-IN-1 is a selective, irreversible inhibitor of bone marrow tyrosine kinase on chromosome X (BMX) that targets Cys496 in the BMX ATP binding domain with an IC50 of 8 nM, also targets the related Bruton’s tyrosine kinase (BTK) with an IC50 value of 10.4 nM, but is more than 47-656-fold less potent against Blk, JAK3, EGFR, Itk, or Tec activity.

1431525-23-3
DC23754 BNC-1

BNC-1 is a small molecule modulator of Amyloid pathology by promoting phosphorylation and activation of Elk-1, a transcriptional repressor of presenilin-1 but not presenilin-2.

96335-59-0
DC7773 BNC-105 Featured

BNC105 is a novel tubulin polymerization inhibitor that selectively disrupts tumor vasculature and displays single-agent antitumor efficacy.

945771-74-4
DC23262 BNM-III-170

BNM-III-170 is a small-molecule CD4-mimetic compound that enhances vaccine efficacy against HIV-1 challenge in vivo.

1859189-54-0
DC23243 BNM-III-170 trifluoroacetate

BNM-III-170 TFA salt is a small-molecule CD4-mimetic compound that enhances vaccine efficacy against HIV-1 challenge in vivo.

1859189-55-1
DC20823 BNS-22

BNS-22 is a small-molecule inhibitor of DNA topoisomerase II, inhibits kinetoplast DNA decatenation that is mediated by human TOP2α and TOP2β in vitro with IC50 of 2.8 and 0.42 uM, respectively.

1151668-24-4
DC22037 Bobcat339 Featured

Bobcat339 (Bobcat 339) is a novel cytosine-based TET enzyme inhibitor with IC50 of 33 uM (TET1) and 73 uM (TET2), but not DNMT3a, does not inhibit the DNA methyltransferase DNMT3a.

2280037-51-4
DC23218 BOC-D-FMK Featured

BOC-D-FMK is a cell-permeable, irreversible, broad spectrum caspase inhibitor, inhibits apoptosis stimulated by TNF-α with IC50 of 39 uM.

634911-80-1
DC20034 Boc-MLF TFA

Boc-MLF (TFA) is a peptide, used as a specific formyl peptide receptor (FPR) antagonist, also inhibits the signaling through formyl peptide receptor like 1 (FPRL1) at higher concentrations.

DC8073 Bohemine Featured

Bohemine is a synthetic, cell-permeable, cyclin-dependent kinase inhibitor.

189232-42-6
DC21869 Borussertib Featured

Borussertib is a potent, first-in-class, covalent-allosteric AKT inhibitor.

1800070-77-2
DC12405 BOS172722 Featured

BOS172722 (BOS-172722) is a potent, selective MPS1 kinase inhibitor with biochemical IC50 of 11 nM, 100-fold selectivity over CDK2.

1578245-44-9
DC5164 Bosutinib (SKI-606) Featured

Bosutinib is a synthetic quinolone derivative and dual kinase inhibitor that targets both Abl and Src kinases with potential antineoplastic activity.

380843-75-4
DC23896 Box5

Box5 is a Wnt5a-derived N-butyloxycarbonyl hexapeptide (t-Boc-Met-Asp-Gly-Cys-Glu-Leu), acts as an Wnt5a antagonist.

881188-48-3
DC20322 BPIPP

BPIPP is an inhibitor of GC-C (guanylyl cyclase type C) that inhibits stimulation of guanylyl cyclase and adenylyl cyclase, suppresses cGMP accumulation in a variety of cell lines (IC50=3.4-11.2 uM).

325746-94-9
DC12608 BPN14770 Featured

BPN14770 (BPN-14770) is an allosteric inhibitor of phosphodiesterase 4D (PDE4D) with IC50 of 7.8 and 7.4 nM for human PDE4D7 and PDE4D3 respectively, displays 16-fold less potent against monomeric form of PDE4D lacking the UCR1 dimerization domain (PDE4D2

1606975-12-5
DC23884 BPN-15606

BPN-15606 (BPN15606) is a highly potent, orally active γ-secretase modulator (GSM), attenuates the production of Aβ42 by SHSY5Y neuroblastoma cells with IC50 of 7 nM.

1914989-49-3
DC8294 BPR1J-097 Featured

BPR1J-097 is a novel small molecule FLT-3 inhibitor(IC50=11±7 nM) with promising in vivo anti-tumour activities; inhibits FLT-3 D835Y with an IC50 of 3 nM.

1327167-19-0
DC21870 BPR1J373

BPR1J373 is a potent, orally available multitargeted kinase inhibitor, potently inhibits FLT3, c-KIT, VEGFR1-3, Aurora A, PDGFRα, PDGFRβ, RET, and SRC with IC50 values of <100 nM.

DC20825 BPR1K653

BPR1K653 is a novel potent Aurora kinase inhibitor that inhibits Aurora-A and Aurora-B with IC50 of 24 nM and 45 nM, respectively.

1192754-06-5
DC7951 Glutaminase Inhibitor II, BPTES Featured

BPTES is a selective inhibitor of Glutaminase GLS1 (KGA)

314045-39-1
DC7542 BQ-788 Featured

BQ-788 sodium salt is a potent, selective ETB receptor antagonist (IC50 = 1.2 nM for inhibition of ET-1 binding to human Girardi heart cells); poorly inhibited the binding to ET A receptors in human neuroblastoma cell line SK-N-MC cells (IC(50), 1300 nM).

156161-89-6
DC10515 BQCA Featured

BQCA is a potent muscarinic M1 receptor positive allosteric modulator with selectivity for M1 over M2-M5.

338747-41-4
DC23763 BQU-082

BQU-082 is a novel potent small GTPase Ral (Ras-like) inhibitor with IC50 of 1.7 uM, displays a dose dependent effect on RalA and RalB activity in H2122 spheroids using the common RalBP1 pull-down assay..

1854910-73-8
DC8202 BQU57 Featured

BQU57 is a potent and selective GTPase Ral Inhibitor.

1637739-82-2
DC12641 BR101549

BR101549 (BR-101549) is a novel PPARγ non-TZD agonist with EC50 of 1.73 uM (Amax 120%)..

2252478-54-7
DC23555 BR103

BR103 is a potent, metabolically stable and highly selective small molecule agonist of complement C3a receptor (C3aR) with EC50 of 22 ± 8  nM.

1434873-26-3
DC23547 BR111

BR111 is a potent, highly selective and orally active antagonist of complement C3a receptor (C3aR) with IC50 of 85 ± 40  nM (inhibition of hC3a induced Ca2+ release on human macrophages).

1037092-93-5
DC20092 BR351

BR351 is a brain penetrant MMP inhibitor with IC50s of 4, 2, 11, 50 nM for MMP2, MMP8, MMP9 and MMP13, respectively. Potential tools for the molecular imaging of activated MMPs with PET.

960113-85-3
DC20096 BR351 precursor

BR351 precursor is a precursor of BR351. BR351 is a brain penetrant MMP inhibitor with IC50s of 4, 2, 11, 50 nM for MMP2, MMP8, MMP9 and MMP13, respectively. Potential tools for the molecular imaging of activated MMPs with PET.

960113-89-7
DC20827 BRACO-19

BRACO-19 is a potent small molecule Telomerase inhibitor (IC50=115 nM) that inhibits expression of human telomerase reverse transcriptase (hTERT).

1177798-88-7
DC7809 BRACO19 trihydrochloride Featured

BRACO19 is a telomerase inhibitor that stabilizes G-quadruplexes, targeting telomeric G-quadruplexes, inducing DNA damage and cell-cycle arrest.

351351-75-2
DC20323 Bractoppin Featured

Bractoppin is a potent, small-molecule chemical inhibitor that specific selectively blocks phosphopeptide recognition by the BRCA1 tBRCT domain with binding IC50 of 74 nM; shows no inhibition for recognition of cognate biotinylated phosphopeptides to the TOPBP1 tBRCT 7/8, or GRB2 SH2 proteins; engages BRCA1 tBRCT residues recognizing pSer in the consensus motif, pSer-Pro-Thr-Phe, plus an abutting hydrophobic pocket; inhibits substrate recognition detected by Förster resonance energy transfer, and diminishes BRCA1 recruitment to DNA breaks, in turn suppressing damage-induced G2 arrest and assembly of the recombinase, RAD51; selectively interrupts BRCA1 tBRCT-dependent signals evoked by DNA damage.

2290527-07-8
DC7775 Bradanicline (TC-5619) Featured

Bradanicline (TC-5619) is an experimental pharmaceutical drugthat acts as a partial agonist at the α7 subtype of the neural nicotinic acetylcholine receptors.

639489-84-2
DC23752 Bragsin1(Bragsin 1)

Bragsin1 (Bragsin 1) is a specific inhibitor of the ArfGEF BRAG2, affects the trans-Golgi network in a BRAG2- and Arf-dependent manner in cells (IC50=3 uM).

369631-68-5
DC12375 Bragsin2 Featured

Bragsin2 is a novel PH-domain-binding inhibitor,inhibiting BRAG2-mediated Arf GTPase activation.

342795-08-8
DC9839 Brassinin Featured

Brassinin is a Inducer of phase II enzymes. Moderate and competitive indoleamine 2,3-dioxygenase inhibitor (Ki = 98 μM). Shows chemopreventive effects in vivo. Orally active.

105748-59-2
DC23100 Brassinolide Featured

Brassinolide is a predominant plant growth modulator that regulate plant cell elongation. It is active against herpes and arena viruses.

72962-43-7
DC23796 BRD 0476

BRD 0476 (ML187) is a selective, moderate inhibitor of ubiquitin-specific peptidase 9X (USP9X), inhibits pancreatic β-cell apoptosis that inhibits IFN-γ-induced JAK2 and STAT1 signaling to promote β-cell survival.

1314958-91-2
DC20842 BRD 7389 Featured

BRD 7389 is an inhibitor of ribosomal S6 kinases (RSK) with IC50 of 1.5 uM, 2.4 uM, and 1.2 uM for RSK1, RSK2, and RSK3, respectively.

376382-11-5
DC20843 BRD 8184

BRD 8184 is a potent, selective HDAC6 inhibitor with IC50 of 8 nM, weakly inhibits HDAC2 and HDAC8 (IC50=0.34 and 1.33 uM),has no activity for HDAC4 (IC50>30 uM)..

1423058-83-6
DC20844 BRD 8430

BRD 8430 is a potent, selective class I HDAC inhibitor (HDAC1>2 >3) with IC50 of 69 nM/560/1300 nM for HDAC1/2/3, respectively.

1482499-16-0
DC20845 BRD 8899

BRD 8899 is a potent and selective inhibitor of the serine/threonine kinase STK33 with IC50 of 0.11 nM (25 uM ATP).

1404437-50-8
DC23341 BRD 9876

BRD 9876 is an ATP- and ADP-competitive Eg5 (kinesin-5) inhibitor with Ki of 4 nM, selectively inhibits microtubule-bound Eg5 and inhibits multiple myeloma cell growth (IC50=2.2 uM).

32703-82-5
DC20828 BRD0209

BRD0209 is a highly selective, potent, reversible, ATP-competitive GSK3 inhibitor with IC50 of 19 nM/5 nM for GSK3α/GSK3β respectively.

1597439-87-6
DC20838 BRD0705 Featured

BRD0705 is a potent, paralog-selective GSK3α inhibitor with IC50 of 66 nM, 8-fold selectivity over GSK3β (IC50=515 nM).

2056261-41-5
DC23008 BRD10330

BRD10330 (BRD-10330) is a small molecule that upregulates IL-10 production in BMDCs.

2174006-11-0
DC20829 BRD1172

BRD1172 is a highly selective, potent, reversible, ATP-competitive GSK3 inhibitor with IC50 of 3 nM/10 nM for GSK3α/GSK3β, respectively..

1597438-86-2
DC23561 BRD1240

BRD1240 is a small-molecule probe that can suppress V-ATPase function, inhibits lysosomal acidification and blocks the maturation of autophagosomes to autolysosomes.

1304759-66-7
DC20830 BRD1652

BRD1652 is a highly selective, potent, reversible, ATP-competitive GSK3 inhibitor with IC50 of 0.4 nM/4 nM for GSK3α/GSK3β respectively.

1597438-92-0
DC20831 BRD2492 Featured

BRD2492 is a highly potent, selective HDAC1/2 inhibitor (IC50=2/19 nM, respectively) that displays excellent selectivity versus HDAC3 (IC50=2.08 uM, ≥110-fold selectivity) and all other HDAC isoforms, increases caspase-3 activation..

1821669-43-5
DC22038 BRD2879

BRD2879 (BRD-2879) is a potent, selective inhibitor of IDH1-R132H mutant with IC50 of 50 nM, inhibits cell-based production of R-2HG with EC50 of 0.3 uM.

1304750-47-7
DC20832 BRD3308 Featured

BRD3308 is a potent, selective HDAC3 inhibitor with IC50 of 54 nM, displays >20-fold selectivity over HDAC1 and HDAC2, >500-fold selectivity over other HDAC isoforms.

1550053-02-5
DC20839 BRD3731

BRD3731 is a potent, selective GSK3β inhibitor with IC50 of 15 nM, 14-fold selectivity for GSK3β over GSK3α (IC50=215 nM).

2056262-08-7
DC12426 BRD4 inhibitor Compound V

BRD4 inhibitor Compound V is a domain-selective inhibitor of BRD4 with IC50 of 1.8 uM for BRD4 BD1, displays 6- and 16-fold selectivity for BRD4 over BRD2 and BRD3, respectively.

DC23880 BRD50837

BRD50837 is a potent, selective, small-molecule inhibitor of the Sonic Hedgehog (Shh) pathway with EC50 of 90 nM, partially lowers Gli1 expression at concentrations of 2 uM, a useful probe of Shh signaling pathway. .

1314295-24-3
DC20833 BRD5459

BRD5459 is a nontoxic enhancer of reactive oxygen species (ROS) that strongly elevates markers of oxidative stress without causing cell death, ROS inducer..

612037-58-8
DC20840 BRD5529

BRD5529 is a small-molecule inhibitor that disrupts the interaction of CARD9-E3 ubiquitin ligase TRIM62 with IC50 of 8.6 uM.

1358488-78-4
DC20834 BRD56491

BRD56491 is a nontoxic enhancer of reactive oxygen species (ROS) that strongly elevates markers of oxidative stress without causing cell death, ROS inducer..

14756-26-4
DC22711 BRD5814 Featured

BRD5814 is a potent, selective, highly brain penetrant β-arrestin biased dopamine D2 receptor (D2R) antagonist with Ki of 0.27 uM.

1953181-29-7
DC23885 BRD6851

BRD6851 is a potent, cell-active Hedgehog (Hh) pathway inhibitor with IC50 of 0.4 uM against C3H10T1/2 cells undergoing Hh-induced activation acts predominantly as Smo antagonist.

1396152-06-9
DC8409 BRD7552 Featured

BRD7552 is an inducer of transcription factor PDX1, which increases insulin expression.

1137359-47-7
DC20836 BRD9092

BRD9092 is a nontoxic enhancer of reactive oxygen species (ROS) that strongly elevates markers of oxidative stress without causing cell death, ROS inducer..

330662-92-5
DC23874 BRD9526

BRD9526 is a potent, small-molecule inhibitor of the Sonic Hedgehog (Shh) pathway with EC50 of 60 nM, partially lowers Gli1 expression at concentrations of 10 uM, a useful probe of Shh signaling pathway. .

1446352-30-2
DC20837 BRD9757

BRD9757 is a potent, selective HDAC6 inhibitor with IC50 of 8 nM, displays >20-fold selectivity over HDAC1/3 and other HDAC isoforms..

1423058-85-8
DC23373 BRD9-IN-28

BRD9-IN-28 is a highly potent and selective BRD7/9 bromodomain inhibitor with pIC50 of 6.9, Kd of 68 nM for BRD9.

1947372-67-9
DC23356 BRD-IN-17

BRD-IN-17 is a cell permeable, family VIII bromodomain tool compound with additional PB1(2) activity over and above that of PFI-3.

1914047-59-8
DC23367 BRD-IN-26

BRD-IN-26 is a potent bromodomain inhibitor that binds the fifth bromodomain of PB1 with a KD of 124 nM, SMARCA2B and SMARCA4 with KD values of 262 and 417 nM, respectively.

1915012-19-9
DC2091 Brefeldin A

Brefeldin A is a lactone antibiotic and ATPase inhibitor for protein transport with IC50 of 0.2 μM in HCT 116 cells.

20350-15-6
DC20981 Brequinar sodium Featured

Brequinar sodium (DuP-785, Brequinar, NSC 368390) is a potent and selective inhibitor of DHODH with IC50 of 20 nM, triggers differentiation in the ER-HoxA9, U937, and THP1 cells with an ED50 of 1 uM.

96201-88-6
DC8179 Briciclib(ON 013105,ON 014185) Featured

Briciclib is a small molecule that suppresses cyclin D1 accumulation in cancer cells.

865783-99-9
DC23147 Brigatinib (AP-26113) Featured

Brigatinib (AP-26113, AP26113) is a potent, selective, second generation ALK inhibitor with IC50 of 0.62 nM, exhibits about fivefold greater potency in vitro compared with crizotinib.

1197953-54-0
DC4165 Brinzolamide

Brinzolamide is a potent carbonic anhydrase II inhibitor with IC50 of 3.19 nM.

138890-62-7
DC9535 Brivaracetam Featured

Brivaracetam(UCB-34714) is a 4-substituted pyrrolidone butanamide as agent with significant antiepileptic activity; high affinity SV2A ligand and also shows an ability to inhibit Na+ channels.

357336-20-0
DC10383 Brivudine

Brivudine is a thymidine analogue with antiviral activity, indicated for the early treatment of acute herpes zoster.

69304-47-8
DC21871 BRK inhibitor P21d

BRK inhibitor P21d is a potent, selective, cell permeable inhibitor of breast tumor kinase (Brk, PTK6) with IC50 of 30 nM, shows no inhibitory activity against Aurora B and Lck (IC50>20 uM).

1338249-87-8
DC23461 BRL 37344 sodium

BRL 37344 is a potent and selective β3 adrenoceptor agonist with Ki of 287 nM.

127299-93-8
DC7891 BRL 52537 HYDROCHLORIDE

BRL 52537 is a selective κ/μ opioid receptor agonist.

112282-24-3
DC20180 BRL-50481 Featured

BRL-50481 is a novel and selective inhibitor of phosphodiesterase (PDE) 7 with a Ki value, derived from secondary (Dixon) plots, of 180±10 nM, being at least 200-fold selective for hrPDE7A1 over all other PDEs.

433695-36-4
DC9124 Bromhexine HCl

Bromhexine Hydrochloride is a medication prescribed for coughs which works by dissolving hard phlegm.

611-75-6
DC22426 Bromocriptine

Bromocriptine (2-Bromoergocriptine.

25614-03-3
DC23899 Bromocriptine mesylate Featured

Bromocriptine (CB-154) is a dopamine D2 receptor agonist (Ki=3 nM) and and various serotonin receptors, also inhibits the release of glutamate by reversing the glutamate GLT1 transporter.

22260-51-1
DC8386 Bromodeoxyuridine (BrdU) Featured

Bromodeoxyuridine (BrdU) is a nucleoside analog that competes with thymidine for incorporation into DNA, and used in the detection of proliferating cells.

59-14-3
DC7543 Bromosporine Featured

Bromosporine is a broad spectrum bromodomain inhibitor. Accelerates FRAP recovery of BRD4 and CREBBP in cells at a concentration of 1 μM.

1619994-69-2
DC12633 Bromotriazine

Bromotriazine (BTZ) is a covalent probe against bromodomain containing proteins with selectively targeting non-catalytic, highly conserved amino acid residues..

DC23385 BRPF1B TRIM24-IN-34

BRPF1B TRIM24-IN-34 is a selective BRPF1B/TRIM24 dual inhibitor that binds with KD of 137 and 222 nM, respectively.

1242907-48-7
DC10460 BT-11 Featured

BT-11 is an orally active and selective LANCL2 modulator.

1912399-75-7
DC10164 BTB-1 Featured

BTB-1 is a small molecule inhibitor of the mitotic motor protein Kif18A.

86030-08-2
DC20199 BTK inhibitor 1;Compound 27 Featured

BTK inhibitor 1 (Compound 27)

2230724-66-8
DC26026 Btk inhibitor 2

Btk inhibitor 2 is a Bruton's tyrosine kinase (BTK) inhibitor extracted from patent US 20170224688 A1.

1558036-85-3
DC12432 BTK inhibitor 4b

BTK inhibitor 4b is a potent, highly selective inhibitors of BTK with IC50 of 4.2 and 0.9 nM against activated and unactivated BTK, respectively.

1646608-10-7
DC11431 BTK-030

BTK-030 is a novel BTK inhibitor.

2241732-30-7
DC23870 BTK-IN-23

BTK-IN-23 is a highly potent and selective Btk inhibitor with IC50 of 3 nM.

1227206-13-4
DC23413 BTRX335140 Featured

BTRX-335140 (CYM-53093, BTRX335140, CYM53093) is a potent, selective, orally active κ opioid receptor (KOR) antagonist with IC50 of 0.8 nM.

2244614-14-8
DC12456 BTT-266 Featured

BTT-266 (BTT266) is a voltage-gated CaV2.2 calcium channel inhibitor that disrupts the CaVα·CaVβ3 protein-protein interaction, directly binds to CaVβ3 with Kd of 3.6 uM.

2413939-89-4
DC12457 BTT-369

BTT-369 (BTT369) is a voltage-gated CaV2.2 calcium channel inhibitor that disrupts the CaVα·CaVβ3 protein-protein interaction with Ki of 2.0 uM in FP assays.

DC23703 BTYNB Featured

BTYNB is a potent and selective inhibitor of IMP1 binding to c-Myc mRNA with IC50 of 5 uM.

304456-62-0
DC22041 BTZO-1 Featured

BTZO-1 is a cardioprotective agent and Macrophage migration inhibitory factor (MIF) activator, binds to MIF with Kd of 68.6 nM, regulates ARE-mediated gene expression.

99420-15-2
DC22042 BTZO-15

BTZO-15 is an active BTZO-1 derivative for ARE-activation with a favorable ADME-Tox profile, induces expression of heme oxygenase-1 (HO-1) and inhibits NO-induced cell death in IEC-18 cells.

916799-65-0
DC22043 BTZO-2

BTZO-2 is an active BTZO-1 derivative, an antioxidant response element-activator, provides protection against lethal endotoxic shock in mice..

501375-54-8
DCAPI1209 Budesonide

Budesonide

51333-22-3
DC6501 Bufalin Featured

Bufalin inhibits steroid receptor coactivator 1 (SRC-1) and SRC-3 at doses as low as 5 nM, promotes the degradation of SRC-3 protein, and inhibits cancer cell growth both in vitro and in vivo.

465-21-4
DCAPI1160 Buflomedil HCl

Buflomedil HCl

35543-24-9
DCAPI1459 Bupivacaine HCL

Bupivacaine HCL

18010-40-7
DC22437 Burimamide oxalate

Burimamide oxalate is a potent dual H3/H2 receptor antagonist with Ki of 0.07 and 7.8 uM, respectively.

163932-06-7
DC20059 Burixafor hydrobromide (TG-0054 hydrobromide)

Burixafor hydrobromide (TG-0054 hydrobromide) is an orally bioavailable and potent antagonist of CXCR4 and a well water soluble anti-angiogenic drug that is of potential value in treating choroid neovascularization. Burixafor hydrobromide (TG-0054 hydrobr

1191450-19-7
DC8995 Busulfan/Myleran

Busulfan is a bifunctional alkylating agent.

55-98-1
DCAPI1407 Butenafine

Butenafine

101828-21-1
DC21685 BVT-948 Featured

BVT-948 (SPS8I-3) is a noncompetitive, cell-permeable inhibitor of protein tyrosine phosphatases (PTPs) with IC50 of 0.09-1.7 uM. Results show that the effect of BVT948 (BVT.948) is to strengthen the insulin signal and has no effects on the duration of th

39674-97-0
DC20852 BX-320

BX-320 is a potent, selective and ATP-competitive inhibitor of PDK1 with IC50 of 30 nM, >20-fold selectivity over PKA.

702676-93-5
DC8808 BX-513 hydrochloride Featured

BX-513 hydrochloride inhibits MIP-1α-induced intracellular calcium mobilization (IC50 = 2.5 μM).

193542-65-3
DC8062 BX517 Featured

BX517 is a novel phosphoinositide-dependent kinase-1 (PDK1) inhibitor.

850717-64-5
DC22424 BX-667

BX-667 is a potent P2Y12 receptor antagonist that blocks ADP-induced platelet aggregation in human, dog and rat blood (IC50=97, 317 and 3000 nM respectively).

937395-08-9
DC7094 Alpelisib(BYL-719) Featured

BYL719 is a potent and selective PI3Kα inhibitor with IC50 of 5 nM, ;liitle or no effect on PI3Kβ/γ/δ.

1217486-61-7
DC20853 BZ-194

BZ-194 is a small molecule inhibitor of NAADP action that inhibit NAADP-mediated Ca2+ signaling in T cells, neither interferes with Ca2+ mobilization by IP3 or cyclic ADP-ribose nor with capacitative Ca2+ entry.

936356-28-4
DC20326 BzDANP

BzDANP is a small molecule modulator of pre-miR-29a maturation by Dicer, effectively stabilizes the C-bulged RNA and suppresses Dicer-mediated processing of pre-miR-29a in a concentration dependent manner..

1994258-88-6
DC26049 Bz-IEGR-pNA (acetate) Featured

Bz-IEGR-pNA is a colorimetric substrate for Factor Xa.

1325307-57-0
DC11453 Bz-Nle-Lys-Arg-Arg-AMC Featured

Bz-Nle-Lys-Arg-Arg-AMC is a substrate for dengue virus NS2B-NS3 and yellow fever virus NS3 protease.

863975-32-0
DC23462 C-021 dihydrochloride

C-021 dihydrochloride is a potent and orally bioavailable CCR4 antagonist with IC50 of 0.14 uM and 0.039 uM for inhibition of chemotaxis in human and mouse, respectively..

1784252-84-1
DC23414 C-021

C-021 is a potent and orally bioavailable CCR4 antagonist with IC50 of 0.14 uM and 0.039 uM for inhibition of chemotaxis in human and mouse, respectively..

864289-85-0
DC20855 C-215

C-215 is a novel inhibitor of mycobacterial membrane protein large 3 (MmpL3) with MIC90 of 16 uM against M. tuberculosis..

912780-51-9
DC20327 C450-0730

C450-0730 is a potent LuxN antagonist that antagonizes LuxN-AI-1 binding with IC50 of 2.7 uM.

1036730-46-7
DC20328 C5-benzyl SAHA

C5-benzyl SAHA is a C5-modified SAHA analog that displays dual selectivity to HDAC6 (IC50=0.27 uM) and HDAC8 (IC50=0.38 uM) over HDAC 1, 2, and 3 (IC50=2.9-5.8 uM).

2115700-64-4
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