Home > Inhibitors & Agonists > Others
Cat. No. Product name CAS No.
DC12044 CA-5f Featured

CA-5f is a novel late-stage autophagy inhibitor with potent anti-tumor effect against non-small cell lung cancer.

1370032-19-1
DC26013 Cabotegravir Sodium Featured

Cabotegravir is a potent HIV integrase inhibitor as an oral lead-in tablet and long-acting injectable for the treatment and prevention of HIV infection.

1051375-13-3
DC8180 Cabotegravir(GSK744) Featured

Cabotegravir is a potent HIV integrase inhibitor as an oral lead-in tablet and long-acting injectable for the treatment and prevention of HIV infection.

1051375-10-0
DC10736 CaCC(inh)-A01 Featured

CaCC(inh)-A01 is a non-selective inhibitor of calcium-activated chloride channels (CaCCs) that blocks ATP-stimulated chloride conductance in human salivary gland, intestinal, and bronchial epithelium (mean IC50 = 10 µM).

407587-33-1
DC20856 CAD-031 Featured

CAD-031 (CAD31) is a novel brain penetrant, J147-derivative that has enhanced neurogenic activity over J147 in human neural precursor cells (NPCs).

2071209-49-7
DC10457 Cadazolid (ACT-179811) Featured

Cadazolid (ACT-179811) is a novel fluoroquinolone-oxazolidinone antibiotic and a protein synthesis inhibitor.

1025097-10-2
DC10327 Calcitonin salmon Featured

Calcitonin, Salmon is a calcium regulating hormone secreted from mammalian thyroid parafollicular cells and in non-mammalian species from the ultimobranchial gland.

47931-85-1
DCAPI1351 Calcium levofolinate (Calcium Folinate)

Calcium levofolinate (Calcium Folinate)

80433-71-2
DC12253 Calcium polystyrene sulfonate (Poly(styrenesulfonic acid) calcium salt)

Calcium polystyrene sulfonate is an ion-exchange resin used for reducing blood levels of potassium. Calcium polystyrene sulfonate is used to treat hyperkalemia in patients with chronic kidney disease (CKD).

37286-92-3
DC20857 Calhex-231 Featured

Calhex-231 is a potent negative allosteric modulator of CaSR that blocks calcium-mediated activation with IC50 of 0.39 uM.

652973-93-8
DC20329 Calindol hydrochloride

Calindol hydrochloride is a calcimimetic acting agent and positive allosteric modulator (agonist) of CaSR with EC50 of 0.31 uM (stimulated 3H IP accumulation in CHO cells at 2 mM Ca2+).

729610-18-8
DC20021 Calmidazolium chloride (R 24571) Featured

Calmidazolium chloride (R 24571) is a calmodulin (CaMK) antagonist, antagonizing CaM-dependent phosphodiesterase and calmodulin-induced activation of erythrocyte Ca2+-transporting ATPase with IC50s of 0.15 and 0.35 μM, respectively. Also in anti-cancer re

57265-65-3
DC7095 W-7 hydrochloride Featured

Calmodulin antagonist. Inhibits Ca2+-calmodulin-dependent phosphodiesterase (IC50 = 28 μM) and myosin light chain kinase (IC50 = 51 μM).

61714-27-0
DC7967 calpeptin Featured

calpeptin is Ca2+-dependent protease,calpain inhibitor

117591-20-5
DC22045 CAM4066

CAM4066 (CAM-4066) is a potent and selective CK2α inhibitor with Kd of 0.32 uM and IC50 of 0.37 uM, shows significantly improved selectivity compared to other CK2α inhibitors. .

2101206-81-7
DC22046 CAM4712

CAM4712 (CAM-4712) is a potent and selective CK2α inhibitor with IC50 of 7 uM, exhibits cell growth inhibition in HCT116 cell line with IC50 of 10 uM.

DC20330 CAMKK2 inhibitor 4t

CAMKK2 inhibitor 4t is a potent, selective, orally available, brain-penetrant CAMKK2 inhibitor with pIC50 of 8.5.

DC10377 Campesterol

Campesterol is a plant sterol with cholesterol lowering and anticarcinogenic effects.

474-62-4
DC20859 CAN-508 Featured

CAN-508 is a potent, selective CDK9 inhibitor with IC50 of 0.35 uM (CDK9/cyclin T1), displays >35 fold selectivity over CDK1/2/4/7 (IC50=13.5-70 uM).

140651-18-9
DC7825 Canagliflozin hemihydrate

Canagliflozin 0.5 H2O(JNJ 28431754; TA 7284) is a highly potent and selective SGLT2 inhibitor for hSGLT2 with IC50 of 2.2 nM, exhibits 413-fold selectivity over hSGLT1.

928672-86-0
DC22425 Cangrelor sodium Featured

Cangrelor (AR-C69931MX) is a potent, selective P2T/P2Y12 receptor antagonist with IC50 of 0.4 nM against ADP-induced aggregation of human platelets.

163706-36-3
DC4154 Capecitabine Featured

Capecitabine is a tumor-selective fluoropyrimidine carbamate which achieves higher intratumoral 5-FU level with lower toxicity than 5-FU.

154361-50-9
DC7615 Capromorelin Featured

Capromorelin tartrate is a potent ghrelin receptor agonist/growth hormone secretagogue (Ki = 7 nM).

193273-69-7
DC26044 Caprooyl-Tetrapeptide-3

Caprooyl tetrapeptide-3 is a derivative of tetrapeptide-3 that is linked to caproic acid.

1012317-71-3
DC7952 Capasazepine Featured

Capsazepine is a synthetic analogue of the sensory neurone excitotoxin, capsaicin; potent TRPV1 receptor antagonist with IC50 of 562 nM.

138977-28-3
DC20331 Capstafin

Capstafin is a phosphorylation of capsaicinoid derivative that acts as a highly potent, selective inhibitor of STAT5b with Ki of 0.34 uM.

1818390-52-1
DC21586 Capzimin

Capzimin (Rpn11 inhibitor 3027) is a derivative of 8TQ, and potent and specific inhibitor of proteasome isopeptidase Rpn11 with IC50 of 0.34 uM, >7-fold improved potency over 8TQ (quinoline-8-thiol).

2084867-65-0
DCAPI1210 Carbazochrome sodium sulfonate

Carbazochrome sodium sulfonate

51460-26-5
DC9173 Carbetapentane citrate

Carbetapentane citrate is a selective inhibitor of the cough, with mild atropine-like effect and local anesthesia effect.

23142-01-0
DC12087 Carboxy pyridostatin trifluoroacetate salt

Carboxy pyridostatin trifluoroacetate salt has the peculiarity to exhibit high molecular specificity for RNA over DNA G4s.

DC6502 cardamonin Featured

Cardamonin, isolated from the fruits of Alpinia species, is a chalconoid with anti-inflammatory and anti-tumor activity.

19309-14-9
DC8456 Cardiogenol C (hydrochloride) Featured

Cardiogenol C is a diaminopyrimidine that induces cardiomyogenesis in mouse embryonic stem cells.

671225-39-1
DC24127 Cardiogenol C hydrochloride

Cardiogenol C is a small cell-permeable molecule that selectively and efficiently induce mouse embryonic stem cells (ESCs) to differentiate into cardiomyocytes with EC50 of 0.1 uM.

1049741-55-0
DC23875 Cardionogen 1

Cardionogen 1 (CDNG1) is a small molecule that promotes cardiomyocyte generation by modulating Wnt signaling.

577696-37-8
DC23881 Cardionogen 2

Cardionogen 2 (CDNG2) is a small molecule that promotes cardiomyocyte generation by modulating Wnt signaling.

578755-52-9
DC9012 Carisoprodol

Carisoprodol is a centrally acting skeletal muscle relaxant of the carbamate class and produces all the effects associated with barbiturate receptor ligands.

78-44-4
DC21875 CARM1 inhibitor 9

CARM1 inhibitor 9 is a potent, selective inhibitor of arginine methyltransferase 1 (CARM1, PRMT4) with IC50 of 94 nM.

2180931-09-1
DC24110 CARM1-IN-1 Featured

CARM1-IN-7g is a potent, selective coactivator-associated arginine methyltransferase 1 (CARM1) with IC50 of 8.6 uM, exhibits lower or no activity against a panel of different PRMTs or HKMTs (>80-fold over PRMT1 and SET7).

1020399-49-8
DC8972 Carmustine Featured

Carmustine is a cell-cycle phase nonspecific alkylating antineoplastic agent.

154-93-8
DC20119 Carnostatine (SAN9812)

Carnostatine (SAN9812) is a specific and highly selective carnosinase (CN1) inhibitor with a Ki of 11 nM.

DC9119 Carvedilol

Carvedilol(BM14190) is a non-selective beta blocker/alpha-1 blocker with an IC50 of 3.8 μM for inhibition of LDL oxidation.

72956-09-3
DC10539 POL1 inhibitor(POL1-IN-1) Featured

CAS 1822358-25-7

1822358-25-7
DC8013 CASIN Featured

CASIN is a Cdc42 GTPase inhibitor (IC50 = 2 μM).

425399-05-9
DC22402 Casopitant

Casopitant (GW679769) is a potent, centrally-acting neurokinin 1 (NK1) receptor antagonist (pKi=9.48) with antidepressant and antiemetic activities.

414910-27-3
DC22403 Casopitant mesylate Featured

Casopitant (GW679769) is a potent, centrally-acting neurokinin 1 (NK1) receptor antagonist (pKi=9.48) with antidepressant and antiemetic activities.

414910-30-8
DC22047 CAT639

CAT639 is an improved analog of ATV399 that exhibits improved β-cell viability and insulin secretion in the rat insulin-producing INS1E cells and primary rat dispersed islet cells, inhibits dimerization of iNOS.

DCAPI1130 Catharanthine

Catharanthine inhibits nicotinic receptor mediated diaphragm contractions with IC50 of 59.6 µM.

2468-21-5
DC22206 Cathepsin B inhibitor RC1

Cathepsin B inhibitor RC1 is a small-molecule that blocks the process of anthrax lethal toxin (LT) cytotoxicity, inhibits enzymatic activity of host cathepsin B that mediates the escape of toxins into the cytoplasm from late endosomes.

775573-79-0
DC10903 CAY10465 Featured

CAY10465 is an analog of resveratrol acting as a potent and selective aryl hydrocarbon receptor agonist, with a Ki of 0.2 nM.

688348-33-6
DC10516 LW6(CAY10585) Featured

CAY10585 prevented HIF-1 transcriptional activity with IC50 values of 2.6 and 0.7 µM, respectively.

934593-90-5
DC20607 Cazpaullone

Cazpaullone (9-Cyano-1-azapaullone) is a derivative of 1-Azakenpaullone, a potent, selective GSK3β inhibitor with IC50 of 8 nM, weakly inhibits CDK1/cyclin B and CDK5/p25 (IC50=0.5 and 0.3 uM).

914088-64-5
DC22986 CB5305630

CB5305630 is a potent and noncompetitive IRE1 RNase inhibitor with IC50 of 60 nM in the FRET-derepression assay.

342388-50-5
DC20861 CB-618

CB-618 (CB 238618) is a novel non-β-lactam β-lactamase inhibitor that potentiates meropenem MIC values against clinical Enterobacteriaceae isolates.

1463520-70-8
DC20862 CB-618 sodium salt

CB-618 (CB 238618) is a novel non-β-lactam β-lactamase inhibitor that potentiates meropenem MIC values against clinical Enterobacteriaceae isolates.

1628207-16-8
DC20052 CB-6644 Featured

CB-6644 is a selective inhibitor of RUVBL1/2 complex with anti-cancer activity. CB-6644 blocks the ATPase activity of RUVBL1/2 with an IC50 of 15 nM.

2316817-88-4
DC20863 CB-6673567

CB-6673567 is a potent, selective Adenylyl Cyclase 1 (AC1) inhibitor with IC50 of 77 uM, displays a 2- to 4-fold isoform selectivity over AC6.

379218-90-3
DC10449 CB7921220 Featured

CB7921220 is an inhibitor of Adenylyl Cyclase isoform-1 (AC1) and isoform-6 (AC6).

115453-99-1
DC8042 CB-839(Telaglenastat) Featured

CB-839 is a potent, selective, reversible and orally bioavailable inhibitor of human glutaminase.

1439399-58-2
DC12623 CBK289001

CBK289001 (CBK-289001) is a small molecule inhibitor of Tartrate-resistant acid phosphatase (TRAP/ACP5), demonstrates efficacy in a migration assay and IC50 values from 4 to 125 uM..

1212663-24-5
DC20866 CC-671 Featured

CC-671 is a potent, selective, dual TTK (Mps1)/CLK2 inhibitor with IC50 of 5/3 nM, respectively.

1618658-88-0
DC12532 CC-90003

CC-90003 (CC90003) is a potent and selective, covalent ERK1/2 inhibitor with IC50 of 10-20 nM, demonstrates excellent selectivity in a 258-kinase biochemical assay panel.

1621999-82-3
DC12590 CCB 02 Featured

CCB02 (CCB 02) is a specific small molecule inhibitor of CPAP-tubulin interaction with IC50 of 0.689 uM in AlphaScreen assay, selectively binds at the CPAP binding site of tubulin.

2100864-57-9
DC23540 CCC07-01

CCC07-01 (CCC 0701) is a novel alkylating compound that is capable of disrupting expression of PD-1, PD-L1 and CTLA-4 genes with IC50 of 15, 10 and 5 nM in cell-base assays.

2215102-35-3
DC7319 CCDC(TGR5-Receptor-Agonist) Featured

CCDC is a otent, selective TGR5 G-protein coupled receptor agonist (pEC50 = 6.8).

1197300-24-5
DC9757 CCF642 Featured

CCF642 is a novel protein disulfide isomerases (PDI) inhibitor.

346640-08-2
DC20867 CCG 102487

CCG 102487 is a CCG-2979 analog that reduces streptokinase (SK) activity with little inhibition of group A streptococcal (GAS) growth.

353787-50-5
DC20871 CCG 2979

CCG 2979 is a small molecule inhibitor of gene expression of streptokinase (SK), a critical group A streptococcal (GAS) virulence factor.

328070-87-7
DC7979 CCG1423 Featured

CCG-1423 is a novel inhibitor of RhoA/C-mediated gene transcription that is capable of inhibiting invasion of PC-3 prostate cancer cells in a Matrigel model of metastasis.

285986-88-1
DC10535 CCG-203971 Featured

CCG-203971 is an inhibitor of SRE activation in the prostate cancer cell line PC-3 (IC50 = 6.4 μM), with 87% inhibition of SRE activation achieved at 100 μM.

1443437-74-8
DC11302 CCG215022 Featured

CCG215022 is a G protein-coupled receptor kinases (GRKs) inhibitor with IC50s of 0.15±0.07 μM, 0.38±0.06 μM and 3.9±1 μM for GRK2, GRK5 and GRK1, respectively.

1813527-81-9
DC10977 CCG-222740

CCG-222740 (CCG222740) is a pharmacological inhibitor of MRTF/SRF signalling, shows greater inhibitory effect on MRTF/SRF target genes than MRTF-A inhibitor CCG-203971, with IC50 of 5 uM in fibroblast-mediated collagen contraction assay.

1922098-69-8
DC20869 CCG-232601

CCG-232601 is a potent (IC50=0.55 uM), orally bioavailable Rho/MKL1/SRF transcriptional pathway that target transcriptional factor MRTF.

1922099-21-5
DC22819 CCG-50014 Featured

CCG-50014 is the most potent against the regulator of G-protein signaling protein type 4 (RGS4) (IC50 =30 nM) and is >20-fold selective for RGS4 over other RGS proteins. CCG-50014 binds covalently to the RGS, forming an adduct on two cysteine residues located in an allosteric regulatory site. CCG50014, reduces nociceptive responses and enhances opioid-mediated analgesic effects in the mouse formalin test.

883050-24-6
DC9612 CCG-63802

CCG-63802 is a reversible inhibitor of regulator of G-protein signaling (RGS) protein; with greatest potency at RGS4. IC50 value: Target: RGS CCG-63802 is selective amongst RGS proteins, with greatest potency at RGS4.

620112-78-9
DC9613 CCG-63808

CCG-63808 is a reversible inhibitor of regulator of G-protein signaling (RGS) proteins.

620113-73-7
DC22050 CCI-006

CCI-006 (CCI 006) is a novel inhibitor of MLL-rearranged and CALM-AF10 translocated leukemias that share common leukemogenic pathways.

292053-42-0
DC22049 CCI-007

CCI-007 (CCI 007) is a selective inhibitor of MLL-r, CALM-AF10 and SET-NUP214 leukemia with IC50 of 3.5 uM against MLL-r leukemia cell line PER-485.

939228-52-1
DC26030 CCMI Featured

CCMI is a positive allosteric modulator of α7 neuronal nicotinic acetylcholine receptors (nAChR).

917837-54-8
DC12639 CCR1 inhibitor 19e

CCR1 inhibitor 19e is a novel potent, selective CCR1 antagonist with IC50 of 6.8 nM, inhibits CCR1chemotaxis in THP-1 cells with IC50 of 28 nM..

1220026-26-5
DC23528 CCR10 antagonist 1

CCR10 antagonist 1 is a potent, selective CCR10 antagonist with IC50 of 690 nM.

1191031-97-6
DC12177 CCR2 antagonist 1

CCR2 antagonist 1 is a high-affinity and long-residence-time CCR2 antagonist, with a Ki of 2.4 nM.

1683534-96-4
DC12302 CCR2 antagonist 3 Featured

CCR2 antagonist 3 is a chemokine receptor 2 (CCR2) antagonist.

1380100-86-6
DC20876 CCT 068127

CCT 068127 (CCT68127) is a novel potent inhibitor of CDK2 and CDK9 with IC50 of 10 and 90 nM for CDK2/E and CDK9/T, respectively.

660822-23-1
DC20875 CCT 365623 hydrochloride

CCT 365623 (CCT365623) hydrochloride is a potent, orally active small molecule inhibitor of lysyl oxidase (LOX) with IC50 of 0.89 uM.

2126136-98-7
DC20874 CCT 365623

CCT 365623(CCT365623, CCT-365623) is a potent, orally active small molecule inhibitor of lysyl oxidase (LOX) with IC50 of 0.89 uM.

2126134-01-6
DC7803 CCT007093 Featured

CCT007093 is a potent PPM1D (WIP1) inhibitor with IC50 of 8.4 μM.

176957-55-4
DC22464 CCT-018159

CCT-01815 is a novel potent inhibitor of Hsp90 ATPase activity with IC50 of 7.1 uM.

171009-07-7
DC20872 CCT-031374

CCT-031374 is a selective β-catenin signaling inhibitor with IC50 of 6.1 uM.

442535-46-8
DC23168 CCT128930

CCT128930 is a potent, selective, ATP-competitive AKT inhibitor with IC50 of 6 nM (AKT2), 28-fold selectivity over the closely related PKA.

885499-61-6
DC23163 CCT129202

CCT129202 is a potent, selective, ATP-competitive pan-Aurora kinase inhibitor with IC50 of 42, 198 and 227 nM for Aurora A, Aurora B and Aurora C, respectively.

942947-93-5
DC23828 CCT241161

CCT241161 is a potent pan-RAF inhibitor with IC50 of 30, 15 and 6 nM for BRAF, V600E-BRAF and C-RAF, also potently inhibits SRC and LCK (IC50=10 and 3 nM, respectively)..

1163719-91-2
DC10911 CCT241736 Featured

CCT241736 is a novel, orally bioavailable Dual FLT3-Aurora Kinase Inhibitor.

1402709-93-6
DC12549 CCX-354

CCX-354 (GSK-2941266, CCX354-C, CCX354) is a potent, selective, orally-available CCR1 antagonist for the treatment of inflammatory diseases such as rheumatoid arthritis (RA)..

1010073-75-2
DC20332 CD38 inhibitor 78c Featured

CD38 inhibitor 78c is a potent, specific, reversible CD38 inhibitor with Ki of 14.5 nM for recombinant human CD38.

1700637-55-3
DC20877 S8

Cdc25 inhibitor S8 is an anti-fungal small molecule that inhibits cdc25 phosphatase with Ki of 140 uM.

1227475-09-3
DC21877 Cdc7 inhibitor

Cdc7 inhibitor is a potent inhibitor of Cdc7 kinase with pIC50 of 10.01 against CDC7/DBF4 in TR-FRET assays..

2206698-92-0
DC22051 CDD-450

CDD-450 is an unique inhibitor that selectively blocks p38α activation of proinflammatory kinase MAPK-MK2 while sparing p38α activation of PRAK and ATF2.

DC8361 CDDO(Bardoxolone; RTA 401) Featured

CDDO is a synthetic oleanane triterpenoid that blocks the cellular synthesis of inducible nitric oxide synthase and inducible COX-2 in INF-γ-activated mouse macrophages with an IC50 value of 0.4 nM.

218600-44-3
DC12026 CDDO-2P-Imidazolide Featured

CDDO-2P-Im is a new analogue of CDDO-Imidazolid,showing better bioactive than CDDO-Imidazolid.

1883650-96-1
DC12027 CDDO-3P-Imidazolide Featured

CDDO-3P-Im is a new analogue of CDDO-Imidazolid,showing better bioactive than CDDO-Imidazolid.

1883650-95-0
DC20334 CDK2 inhibitor 73 Featured

CDK2 inhibitor 73 is a potent, selective CDK2 inhibitor with IC50 of 44 nM for CDK2/cyclin A, displays 2,000-fold selectivity over CDK1/cyclin B (IC50=86 uM)..

2079895-42-2
DC20921 CDK5 inhibitor 20-223

CDK5 inhibitor 20-223 (CP 668863) potent, selective, ATP-competitive CDK2/5 inhibitor with IC50 of 6.0 and 8.8 nM for CDK2/CyclinE and CDK5/p35, with little to no activity against CDK1/4/6/7/9.

865317-30-2
DC12528 CDK9 inhibitor HH1

CDK9 inhibitor HH1 is a novel potent, highly selective CDK9 inhibitor..

204188-41-0
DC20335 CDK9-IN-8 Featured

CDK9-IN-8 is a highly potent, selective CDK9 inhibitor with IC50 of 12 nM, shows good selectivity in CDKs kinase profiling assay against CDK kinases and cell proliferation inhibition.

2105956-51-0
DC23138 CDK-I73 Featured

CDKI-73 is a potent CDK9 inhibitor with Ki of 4 nM, shows cytotoxicity against a broad CLL samples with mean LD50 of 80 nM.

1421693-22-2
DC11393 CDM-NAG Featured

CDM-NAG is a useful tool compound to deliver the siRNA.

1299292-01-5
DC20879 CDP-840

CDP-840 (CDP840.

162542-90-7
DC20880 CDP-840 hydrochloride

CDP-840 (CDP840.

DC23463 CDPPB Featured

CDPPB is a potent, selective, brain penetrant positive allosteric modulator of mGlu5 receptor with EC50 of 10 nM and 20 nM for human and rat mGluR5, respectively.

781652-57-1
DC22446 CE-224535

CE-224535 (PF-04905428) is a potent and selective P2X7 receptor antagonist with IC50 of 1.4 nM (inhibition of the release of lL-1b from monocytes stimulated by ATP).

724424-43-5
DC20881 CE-245677

CE-245677 is a potent, selective, orally active, dual Tie2/Trk kinase inhibitor with IC50 of 4.7 nM, 1 nM for Tie2 and TrkA/B, respectively.

717899-97-3
DC20336 CE3F4 Featured

CE3F4 is a potent, noncompetitive EPAC1 inhibitor that blocks EPAC1-induced Rap1 activation both in cell-free systems and in intact cells and did not influence protein kinase A holoenzyme activity.

143703-25-7
DC23912 Cecropin B

Cecropin B is an antimicrobial peptide with MICs(0.5 to 16 ug/ml) against Gramnegative strains.

80451-05-4
DC20987 Cedazuridine Featured

Cedazuridine (E7727) is a novel cytidine deaminase inhibitor, and a componet of ASTX727 for treatment of hematologic malignancies..

1141397-80-9
DCAPI1386 Cefdinir (Omnicef)

Cefdinir (Omnicef)

91832-40-5
DC8686 Cefetamet pivoxil hydrochloride

Cefetamet pivoxil hydrochloride is an oral third generation cephalosporin antibiotic.

111696-23-2
DC9358 Cefmenoxime (hydrochloride)

Cefmenoxime hydrochloride is a third-generation cephalosporin antibiotic.

75738-58-8
DCAPI1038 Cefoselis sulfate

Cefoselis sulfate

122841-12-7
DC20190 Cefoxitin

Cefoxitin is a beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity.

35607-66-0
DC8067 Cefozopran Featured

Cefozopran (SCE-2787) is a new parenteral cephalosporin, against experimental infections in mice.

113359-04-9
DC9356 Cefpiramide (sodium)

Cefpiramide sodium (SM-1652; Wy-44635) is a new Pseudomonas-active cephalosporin with a broad spectrum of antibacterial activity.

74849-93-7
DC8687 Cefpirome sulfate

Cefpirome Sulfate is a fourth generation cephalosporin antibiotic.

98753-19-6
DCAPI1033 Cefprozil hydrate (Cefzil)

Cefprozil hydrate (Cefzil)

121123-17-9
DC9355 Ceftibuten (dihydrate)

Ceftibuten dihydrate is a third-generation cephalosporin antibiotic.

118081-34-8
DC12245 Ceftizoxime

Ceftizoxime is a bacterial inhibitor which acts by interfering with bacterial cell wall synthesis and inhibiting cross-linking of the peptidoglycan.

68401-81-0
DC7569 Z-LEHD-FMK

Cell permeable fluoromethyl ketone (FMK)-derivatized peptides act as effective irreversible Caspase inhibitors with no cytotoxic effects and, therefore, are useful tools for studying Caspase activity.

210345-04-3
DC23359 CeMMEC2

CeMMEC2 is a novel potent BRD4 inhibitor with IC50 of 0.9 uM, binds to both bromodomains of BRD4, comparably to (S)-JQ1..

902955-25-3
DC10316 Cenicriviroc Featured

Cenicriviroc is an orally active, dual CCR2/CCR5 antagonist, and displays potent anti-inflammatory and aninfective activity.

497223-25-3
DC21554 AS 703569

Cenisertib (AS 703569;R763) is a novel potent, orally available inhibitor of Aurora kinases, exhibits signifficant anti-proliferative activity against a wide range of tumor cells both in vitro and in vivo (A549 EC50=9 nM).

871357-89-0
DC12318 Centanafadine hydrochloride (EB-1020 (hydrochloride))

Centanafadine (hydrochloride) is dual norepinephrine (NE)/dopamine (DA) transporter inhibitor, also inhibits serotonin transporter, with IC50s of 6 nM, 38 nM and 83 nM for human NE, DA and serotonin transporter , respectively.

923981-14-0
DC12319 Centanafadine (EB-1020)

Centanafadine is dual norepinephrine (NE)/dopamine (DA) transporter inhibitor, also inhibits serotonin transporter, with IC50s of 6 nM, 38 nM and 83 nM for human NE, DA and serotonin transporter , respectively.

924012-43-1
DC22796 CEP-1347

CEP-1347 (KT-7515) is a potent and selective MLK inhibitor that completely rescues motoneurons and inhibits JNK1 activation with IC50 of 20 nM.

156177-65-0
DC23856 CEP-7055

CEP-7055 is a potent, orally active, pan inhibitor of VEGFR, CEP-7055 is the dimethylglycine ester prodrug of CEP-5214, which inhibits human VEGFR2/KDR kinase, VEGFR1/FLT-1 kinase, and VEGFR3/FLT-4 kinase with IC50 of 18 nM, 12 nM, and 17 nM.

402857-58-3
DC7347 Cephalosporin C Na salt Featured

Cephalosporin C Na salt is used to study the effect of transpeptidase expression, binding, and inhibition on bacterial cell wall mucopeptide synthesis.

74970-31-3
DC7346 Cephalosporin C zinc salt Featured

Cephalosporin C zinc salt is used to study the effect of transpeptidase expression, binding, and inhibition on bacterial cell wall mucopeptide synthesis.

59143-60-1
DC9649 Cephalotaxlen Featured

Cephalotaxine is an antiviral as well as antitumor agent.

24316-19-6
DC10226 Cefradine

Cephradine is a semi-synthetic cephalosporin antibiotic.

38821-53-3
DC9500 Cevimeline (hydrochloride hemihydrate) Featured

Cevimeline hydrochloride hemihydrate, a novel muscarinic receptor agonist, is a candidate therapeutic drug for xerostomia in Sjogren's syndrome.

153504-70-2
DC7899 Cevipabulin(TTI 237)

Cevipabulin, also known as TTI-237, an antimicrotubule agent, is a small synthetic molecule of triazolopyrimidine derivative with potential antitumor activity.

849550-05-6
DC22052 CFI02

CFI02 (CFI-02) is a specific inhibitor of human cytomegalovirus (HCMV) glycoprotein B-mediated fusion with IC50 of 40 nM against laboratory adapted HCMV strain AD169.

273735-28-7
DC10069 CFI-400437 Featured

CFI-400437 is potent against PLK4 (IC50 = 0.6 nM) and selective against other members of the PLK family (>10 uM).

1247000-76-5
DC23338 CFI-401980

CFI-401980 is a potent, selective, novel class TTK (Tyrosine Threonine Kinase) inhibitor with Ki of 0.8 nM, HCT116 GI50 of 13 nM.

1610676-27-1
DC11133 CFM-4.16

CFM-4.16 is a CARP-1 functional mimetic (CFM) compound bind with CARP-1, stimulates CARP-1 expression and apoptosis.

1426415-28-2
DC22809 c-FMS-IN-8 Featured

c-FMS-IN-8 is a potent, selective c-FMS kinase inhibitor with IC50 of 0.8 nM, shows activity in collagen-induced model of arthritis in mice..

885704-21-2
DC12580 CG-806 Featured

CG-806 (CG806, CG'806) is a novel potent, pan-FLT3/BTK multi-kinase inhibitor with impressive inhibition of leukemic cell proliferation with IC50 at sub-nanomolar or low nanomolar levels.

1370466-81-1
DC7101 CGK733 Featured

CGK 733 is a potent and selective inhibitor of ATM/ATR with IC50 of ~200 nM.

905973-89-9
DC10722 CGP-71683A Featured

CGP 71683A is a potent and highly selective non-peptide antagonist of the NPY Y(5) receptor in the study of obesity.

192322-50-2
DC23919 CGP-42112 Featured

CGP-42112 (CGP42112A) is a highly potent, selective Angiotensin-II subtype 2 receptor(AT2 receptor) agonist with Ki of 0.24 nM.

127060-75-7
DC23830 CGP-53353

CGP-53353 (DAPH-7) is a selective inhibitor of PKCβII with IC50 of 0.41 uM, shows weak activity on PKCβI with IC50 of 3.8 uM.

145915-60-2
DC20887 CGP-74514A hydrochloride

CGP-74514A hydrochloride is a potent CDK1 inhibitor with IC50 of 25 nM.

481724-82-7
DC24112 CGS 21680

CGS 21680 is a specific adenosine A2A subtype receptor agonist with Ki of 27 nM.

120225-54-9
DC21331 CGS 27023A

CGS 27023A (MMI 270) is a potent, orally active MMP inhibitor with Ki of 8-43 nM for MMP1/2/3/9.

169799-04-6
DC7102 CH5132799 Featured

CH5132799 selectively inhibits class I PI3Ks, such as PI3Kα, PI3Kβ, PI3Kδ, and PI3Kγ with IC50 values of 0.014, 0.12, 0.50, and 0.36 uM, respectively; shows less inhibition of class II PI3Ks, class III PI3ks, and mTOR.

1007207-67-1
DC22054 CH5447240 Featured

CH5447240 is a novel potent, selective, orally active hPTHR1 agonist with EC20 of 3.0 nM and EC50 of 12 nM.

1253919-92-4
DC12415 CH7057288 Featured

CH7057288 (CH-7057288) is a novel potent and selective pan-TRK inhibitor with IC50 of 1.1/7.8/5.1 nM for TRKA/TRKB/TRKC, respectively.

2095616-82-1
DC20337 Chaetocin

Chaetocin is a potent, specific, SAM-competitive inhibitor of histone H3K9 methyltransferase (HMT) SU(VAR)3-9 with IC50 of 0.6 uM, no actiivty against H4 Lys20-specific HMT PRSET7 and SET7/9.

28097-03-2
DC5135 Chaetominine

Chaetominine , an alkaloidal metabolite with a new framework, was characterized from the solid-substrate culture of Chaetomium sp.

918659-56-0
DC12545 CHDI-390576

CHDI-390576 (CHDI390576) is a potent, cell permeable and CNS penetrant class IIa HDAC inhibitor with IC50 of 54/60/31/50 nM for HDAC4/5/7/9, respectively.

1629729-98-1
DC23101 Chelerythrine chloride Featured

Chelerythrine is a potent, cell permeable inhibitor of protein kinase C (IC50 = 660 nM) that does not inhibit tyrosine protein kinases, cAMP-dependent protein kinase, or calcium/calmodulin-dependent protein kinase.

3895-92-9
DC20266 Chelerythrine Featured

Chelerythrine is a well-known protein kinase C inhibitor, can inhibit telomerase activity, it also can block the human P2X 7 receptor.

34316-15-9
DC20100 Chelidonic acid Featured

Chelidonic acid is a component of Chelidonium majus L., used as a mild analgesic, an antimicrobial, an acentral nervous system sedative. Chelidonic acid also shows anti-inflammatory activity. Chelidonic acid has potential to inhibit IL-6 production by blo

99-32-1
DC12205 CHEMBL333994 (FK-480)

CHEMBL333994 is a potent and orally effective Cholecystokinin A (CCK-A) antagonist, with an IC50 of 0.67 nM.

167820-10-2
DC20338 Chemocoxib A

Chemocoxib A is a highly potent, selective, cytotoxic COX-2 inhibitor with IC50 of 290 nM and 90 nM for wt mCOX-2 and R120Q COX-2 mutant respectively.

960214-84-0
DC21405 Chetomin Featured

Chetomin (NSC 289491) is a natural product isolated from Chaetomium species which shows antibacterial and antifungal properties, disrupts the interaction of HIF-1α/p300 at low nanomolar concentrations, strongly increases retinal pigment epithelial cells d

1403-36-7
DC12515 Chiglitazar

Chiglitazar (CS-038, CS038) is a potent, dual PPARα/γ dual agonist with EC50 of 1.2, 0.08, 1.7 uM for PPARα, PPARγ and PPARδ, respectively.

1959588-75-0
DC9292 CHIR-090 Featured

CHIR-090 is a potent LpxC inhibitor, displays two-step time-dependent inhibition and kills a wide range of Gram-negative pathogens as effectively as ciprofloxacin or tobramycin.

728865-23-4
DC12323 CHK1-IN-2

CHK1-IN-2 is a checkpoint kinase 1 (CHK1) inhibitor, with an IC50 of 6 nM

912367-45-4
DC9048 Chloroambucil

Chlorambucil(WR-139013; CB-1348) is a chemotherapy drug that has been mainly used in the treatment of chronic lymphocytic leukemia.

305-03-3
DCAPI1255 Chloramphenicol (Chloromycetin)

Chloramphenicol (Chloromycetin)

56-75-7
DC12124 Chlorantraniliprole

Chlorantraniliprole is an insecticide that potently and selectively activates insect ryanodine receptor, with EC50s of 40 nM and 50 nM for Drosophila melanogaster and H. virescens ryanodine receptor, and ∼300-fold more potent than that in the mouse myobla

500008-45-7
DCAPI1167 Chlorhexidine HCl

Chlorhexidine hydrochloride is an antiseptic effective against a wide variety of gram-negative and gram-positive organisms.

3697-42-5
DCAPI1354 Chlormezanone (Trancopal)

Chlormezanone (Trancopal)

80-77-3
DCAPI1270 Chlorothiazide

Chlorothiazide

58-94-6
DCAPI1339 Chlorthalidone (Chlortalidone)

Chlortalidone is a diuretic drug used to treat hypertension.

77-36-1
DC9194 Chlorzoxazone

Chlorzoxazone is a centrally acting muscle relaxant used to treat muscle spasm and the resulting pain or discomfort. It acts on the spinal cord by depressing reflexes.Chlorzoxazone is currently being used as a marker substrate in vitro/vivo studies to qua

95-25-0
DC20623 CHMFL-ABL-053

CHMFL-ABL-053 is a potent, selective and orally available Bcr-Abl/Src/p38 kinase inhibitor with IC50 of 70/62/90 nM.

1808287-83-3
DC20339 CHMFL-KIT-031

CHMFL-KIT-031 is a highly selective KIT kinase primary V559D mutant inhibitor with IC50/Kd of 28/266 nM, 10-20 fold selectivity over KIT wt.

DC20069 CHMFL-PI3KD-317

CHMFL-PI3KD-317 is a highly potent, selective and orally active PI3Kδ inhibitor, with an IC50 of 6 nM, and exhibits over 10-1500 fold selectivity over other class I, II and III PIKK family isoforms, such as PI3Kα (IC50, 62.6 nM), PI3Kβ (IC50, 284 nM), PI3

2244992-76-3
DC12199 Cholestenone

Cholestenone is the intermediate oxidation product of cholesterol.

601-57-0
DC20181 Choline Fenofibrate;ABT-335

Choline fenofibrate is a newly developed choline salt of fenofibric acid, a synthetic phenoxy-isobutyric acid derivate with antihyperlipidemic activity that acts as an PPARα agonist.

856676-23-8
DC22173 CHR-3996

CHR-3996 (Nanatinostat, VRx-3996, CHR3996, Tractinostat) is a potent, class I-selective, orally active HDAC inhibitor with IC50 of 3-7 nM for HDAC1/2/3.

1256448-47-1
DC9460 CHR-6494 Featured

CHR-6494 is a potent and selective Haspin (Haploid Germ Cell-Specific Nuclear Protein Kinase) inhibitor that blocks H3T3ph phosphorylation.

1333377-65-3
DC12329 ChX710

ChX710 could prime the type I interferon response to cytosolic DNA, which induces the ISRE promoter sequence, specific cellular Interferon-Stimulated Genes (ISGs), and the phosphorylation of Interferon Regulatory Factor (IRF) 3.

2438721-44-7
DC20893 CI-1044

CI-1044 is a potent, selective and orally bioavailable PDE4 inhibitor with IC50 of 0.27 uM, displays high selectivity for PDE4 versus PDE1/3/5, and no PDE4 subtype (4A-D) selectivities.

197894-84-1
DC21462 CI-966

CI-966 (PD 126141) is a potent, selective inhibitor of the GABA transporter GAT-1 with IC50 of 0.26 and 1.2 uM for human and rat GAT-1, respectively.

110283-79-9
DC20894 CI-966 hydrochloride

CI-966 is a potent, selective inhibitor of the GABA transporter GAT-1 with IC50 of 0.26 and 1.2 uM for human and rat GAT-1, respectively.

110283-66-4
DC21463 CI-976 Featured

CI-976 (PD 128042) is a potent, selective, orally bioavailable inhibitor of ACAT-1 (Acetyl-CoA acetyltransferase 1) with IC50 of 73 nM.

114289-47-3
DC12412 cIAP1 E3 ligase inhibitor D19

cIAP1 E3 ligase inhibitor D19 (cIAP1 inhibitor D19) is a small-molecule inhibitor of E3 ligase activity of cIAP1, inhibits cIAP1 auto-ubiquitination with IC50 of 14.1 uM, shows no effect on autoubiquitination of BRCA1/BARD1.

380640-76-6
DC12413 cIAP1 E3 ligase inhibitor D19-14

cIAP1 E3 ligase inhibitor D19-14 (cIAP1 inhibitor D19-14) is an improved analog of D19, demonstrates significantly increased ability to inhibit cIAP1 autoubiquitination and reduce protein levels of c-MYC in vitro.

DC9176 Ciclesonide

Ciclesonide(RPR251526) is a glucocorticoid used to treat obstructive airway diseases.

126544-47-6
DCAPI1143 Ciclopirox (Penlac)

Ciclopirox (Penlac)

29342-05-0
DC12285 CID 1375606 Featured

CID 1375606 is a surrogate agonist of orphan G protein-coupled receptor GPR27.

313493-80-0
DC22056 CID 9998128

CID 9998128 is a potential multi-target drug for the Alzheimer's disease (AD), inhibits the Aβ42 amyloid fibrillization and is capable to clear Aβ42 fibrils.

733807-13-1
DC12243 CID-1067700

CID-1067700 is a pan GTPase inhibitor, and competitively inhibits Ras-related in brain 7 (Rab7) with a Ki of 13 nM.

314042-01-8
DC7253 CID-2011756 Featured

CID-2011756 is a cell-active ATP competitive and specific PKD1 inhibitor that inhibits phorbol ester-induced endogenous PKD1 activation in LNCaP prostate cancer cells.

638156-11-3
DC8849 CID-2858522 Featured

CID-2858522 is a selectively inhibits protein kinase C (PKC)-induced activation of the NF-κB pathway (IC50 < 0.1 μM for PMA-stimulated IL-8 production).

758679-97-9
DC20895 CID3528206

CID3528206 is a potent, small molecule yeast TORC1 inhibitor that inhibits TORC1 activity both in vitro and in vivo with IC50 of 150 nM and 3.9 uM, respectively.

674359-78-5
DC7976 CID 797718 Featured

CID-797718 is a compound with unknown details.

370586-05-3
DC23753 CID888706

CID888706 is a small molecule, pan activator of Rho-family GTPases..

496775-95-2
DC20904 CIDD 0067106

CIDD 0067106 is a novel natural product-based diaryloxazole that potent and selective antiproliferative activities against androgen receptor-positive breast cancer cells (MDA-MB-453 cell GI50=0.8 uM).

2151865-39-1
<Prev1...1617181920...127Next>