Cat. No. | Product name | CAS No. |
DC22696 |
BRL 44408
Featured
A potent, selective α2A-adrenoceptor antagonist with Ki of 1.7 nM, 80-fold selectivity over α2B-adrenergic receptors. |
118343-19-4 |
DC22695 |
BRL 44408 maleate
A potent, selective α2A-adrenoceptor antagonist with Ki of 1.7 nM, 80-fold selectivity over α2B-adrenergic receptors. |
681806-46-2 |
DC22694 |
ARC 239 dihydrochloride
A potent, selective α2B adrenoceptor antagonist with pKd of 8.8, 200-fold selectivity over α2A, and α2D receptors. |
55974-42-0 |
DC22536 |
CFMTI
Featured
A potent, selective, allosteric and oral mGluR1 antaognist with IC50 of 2.6 and 2.3 nM for human and rat mGluR1, respectively. |
864864-17-5 |
DC22753 |
NS13001
Featured
A potent, selective, allosteric and orally acitve positive modulator of small-conductance calcium-activated K+ channel KCa2.2 and KCa2.3 with EC50 of 1.6 and 0.14 uM, respectively. |
1063331-94-1 |
DC21316 |
ML400
A potent, selective, allosteric LMPTP inhibitor with IC50 of 1.68 uM, displays good selective against other phosphatases. |
1908414-42-5 |
DC22916 |
JNJ-10397049
A potent, selective, and bioavailable OX2 receptor antagonist with Kb of 4.5 nM. |
708275-58-5 |
DC23971 |
LY450108
A potent, selective, and centrally active positive allosteric modulator of AMPAR-mediated neurotransmission, which increase ion channel flux in the presence of agonist by suppressing desensitization and/or deactivation of the receptors.. |
376594-67-1 |
DC24030 |
LY451395
A potent, selective, and centrally active positive allosteric modulator of AMPAR-mediated neurotransmission, which increase ion channel flux in the presence of agonist by suppressing desensitization and/or deactivation of the receptors.. |
375345-95-2 |
DC23963 |
QL-47
A potent, selective, and irreversible BTK inhibitor with IC50 of 7 nM. |
1469988-75-7 |
DC21545 |
PXS-4681A
A potent, selective, and irreversible inhibitor of SSAO/VAP-1 (AOC3) with Ki of 37 nM, IC50 of <10 nM. |
1478364-87-2 |
DC21254 |
LY-517717
A potent, selective, and orally bioavailable factor Xa (FXa) inhibitor for prevention and treatment of thromboembolic diseases.. |
313489-71-3 |
DC21487 |
PF-05190457
Featured
A potent, selective, and orally bioavailable ghrelin receptor (GHSR) inverse agonist with binding pKi of 8.36. |
1334782-79-4 |
DC23541 |
IRAK4-IN-16
A potent, selective, and orally bioavailable inhibitor of interleukin-1 receptor-associate kinase-4 (IRAK4) with IC50 of 2.8 nM, 217- and 892-fold selectivity over IRAK-1 and TAK1, respectively. |
509093-72-5 |
DC23949 |
CX-6258 hydrochloride hydrate
A potent, selective, and orally efficacious pan-Pim inhibitor with IC50 of 5/25/16 nM for Pim1/2/3, respectively. |
1353858-99-7 |
DC23036 |
BI-69A11
A potent, selective, ATP competitive AKT inhibitor with IC50 of 2.3 uM for Akt1. |
1233322-09-2 |
DC22651 |
PF-4950834
A potent, selective, ATP-competitive and orally acitve Rho kinase inhibitor with IC50 of 33.1 and 8.5 nM for ROCK1 and ROCK2, respectively. |
1256264-62-6 |
DC23867 |
PF-00337210
A potent, selective, ATP-competitive and orally bioavailable inhibitor of VEGFR-2 with Ki of 0.7 and 8.8 nM for unactivated and fully phosphorylated VEGFR-2, respectively. |
854514-88-8 |
DC23930 |
Bay 65-1942
A potent, selective, ATP-competitive inhibitor of IKKβ kinase with Ki of 2 nM. |
600734-02-9 |
DC22500 |
Bay 65-1942 hydrochloride
A potent, selective, ATP-competitive inhibitor of IKKβ kinase with Ki of 2 nM. |
600734-06-3 |
DC23070 |
MAP4K4-IN-11e
A potent, selective, ATP-competitive inhibitor of MAP4K4 with IC50 of 1.9 uM, without effect on other stress pathway related kinases. |
1774346-60-9 |
DC23964 |
BMS-509744
A potent, selective, ATP-competitive ITK inhibitor with IC50 of 19 nM. |
439575-02-7 |