RO-9187| CAS 876708-03-1|DC Chemicals

Cas No.:	876708-03-1
Chemical Name:	2(1H)-Pyrimidinone, 4-amino-1-(4-C-azido-β-D-arabinofuranosyl)-
Synonyms:	RO 9187;RO9187
SMILES:	[N-]=[N+]=N[C@@]1(O[C@@H](N2C=CC(N)=NC2=O)[C@@H](O)[C@@H]1O)CO
Formula:	C₉H₁₂N₆O₅
M.Wt:	284.2288
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

A potent HCV NS5B RNA polymerase inhibitor; inhibits HCV replication in the replicon system with IC50 of 171 nM; RNA synthesis by HCV polymerases from either HCV genotypes 1a and 1b or containing S96T or S282T point mutations (IC50=600-1100 nM); shows good oral bioavailability in rats and no toxicologically significant findings.

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101
2018-0101

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