| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC60601 | GLP-1-MK-801 Featured | GLP-1-MK-801 is a GLP-1-directed NMDA receptor antagonist for targeting to achieve cell-specifc ionotropic receptor modulation and highlights the therapeutic potential of unimolecular mixed GLP-1 receptor agonism and NMDA receptor antagonism. |
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| DC60602 | Jun12682 Featured | Jun12682 is a SARS-CoV-2 papain-like protease (PLpro) inhibitor with Ki of 37.7 nM and displays EC50 of 1.1 μM in the FlipGFP PLpro assay, more than 20-fold improved from GRL0617 (EC50=22.4 μM). |
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| DC66455 | Stanolone Featured |
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| DC60604 | CDD-2807 Featured | CDD-2807 is a potent serine/threonine kinase 33 (STK33) inhibitor with Kd of 0.02 nM and IC50 of 9.2 nM, respectively. CDD-2807 shows >9-fold selectivity versus other kinases and demonstrates excellent metabolic stability with T1/2 >60 min in MLM and HLM. |
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| DC60605 | Lipid 119-23 Featured | Lipid 119-23 is an ionizable lipid for mRNA delivery. 119-23 LNP exhibits an enhanced capability to express functional mCre in several categories of immune cells, spanning the liver, spleen and lung. |
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| DC60606 | KL-50 Featured | KL-50 is a selective toxin toward tumors that lack the DNA repair protein O6-methylguanine-DNA-methyltransferase (MGMT), which reverses the formation of O6-alkylguanine lesions. KL-50 is the first reported compound to overcome acquired temozolomide resistance while maintaining high selectivity for MGMT-cells. |
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| DC60607 | SL-25.1188 Featured | SL-25.1188 is a monoamine oxidase B (MAO-B) inhibitor potentially for treatment of Alzheimer's dementia and smoking cessation. SL-25.1188 is characterized in vivo by reversible binding, high brain uptake, and very slow plasma metabolism. |
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| DC66456 | TLR7/8 agonist 1 Featured | TLR7/8 agonist 1 is a toll-like receptor (TLR7)/TLR8 dual-agonistic imidazoquinoline. |
|
| DC66457 | FAP-IN-2 (FAPI) Featured | FAP-IN-2 is a derivative of 99mTc-labeled isonitrile-containing fibroblast activation protein (FAPI) inhibitor, that can be used for tumor imaging. |
|
| DC66458 | FAPI -14 Featured |
|
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| DC60608 | SL25.1188 precursor Featured | SL25.1188 precursor is the precursor of SL25.1188. |
|
| DC66459 | NOTA-FAPI Featured | NOTA-FAPI is a fibroblast activation protein (FAP) inhibitor. NOTA-FAPI can be used as a probe for FAP-targeted tumour imaging. NOTA-FAPI has good tumour detection efficacy and excellent imaging quality. |
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| DC66460 | FAPI-4 Featured | FAPI-4 is a potent fibroblast activation protein (FAP) inhibitor for the targeting FAP. FAPI-4 can be used in cancer research. 68Ga-FAPI-4 PET/CT is a promising new diagnostic method for imaging various kinds of cancer, with good tumor-to-background contrast ratios. |
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| DC66461 | SH-FAPI-4 Featured |
|
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| DC66462 | HYINC-FAPI-4 (FAP-IN-2) Featured | HYINC-FAPI-4 is a derivative of 99mTc-labeled isonitrile-containing fibroblast activation protein (FAPI) inhibitor, that can be used for tumor imaging. |
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| DC66463 | FAPI-46-NOTA Featured |
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| DC66464 | 3BP-3940 Featured | 3BP-3940 is a highly potent fibroblast activation protein (FAP)-targeting peptide for theranostics. 3BP-3940 is often coupled with radionuclides for tumor diagnosis and treatment. |
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| DC66465 | Pentanedioate Featured | Pentanedioate is a starting material for the synthesis of specific PSMAM inhibitors. |
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| DC66467 | F-PSMA 1007 Featured |
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| DC66468 | NOTA-octreotide Featured | NOTA-octreotide is a ligand for making [18F]AlF-NOTA-octreotide, which is a PET/CT imaging agent for somatostatin receptor imaging in neuroendocrine tumor patients |
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| DC66469 | DOTA-NOC Featured | DOTA-NOC (DOTA-Nal3-octreotide) is a high-affinity ligand of somatostatin receptor subtypes 2, 3 and 5. DOTA-NOC can be used for labeling with various radiometals, and development of radiopeptide imaging. |
|
| DC66470 | KN-93 phosphate Featured | KN-93 phosphate is a novel membrane-permeant synthetic inhibitor of purified neuronal CaMK-II, with Ki of 370 nM. |
|
| DC66471 | 4-chloro-1-benzothiophene-2-carboxylic acid Featured |
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| DC66472 | 6-bromo-1,2-dimethyl-1H-benzo[d]imidazole Featured |
|
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| DC66473 | SI-80 Featured |
|
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| DC66474 | Benzobthien-2-yl Ketone (Zileuton Impurity) Featured |
|
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| DC66475 | 2-Chloro-5-(methylthio)pyrimidine Featured |
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| DC66476 | Clevidipine Impurity 21 Featured |
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| DC66477 | 5,6,7,8-TETRAHYDRO-4 H-CYCLOHEPTA[ D ]ISOXAZOLE-3-CARBOXYLIC ACID Featured |
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| DC66478 | WAY-312778 Featured | altering the lifespan of a eukaryotic organism |
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