| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC66596 | Bartsiosid Featured | Bartsioside is an anti-inflammatory agent which can be extracted from C. deserticola. Bartsioside exerts no significant cytotoxicity under 40 μM to BV-2 cells. |
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| DC66597 | 1-O-palmityl-D-glucuronic acid Featured |
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| DC66598 | Octadecyl β-D-glucopyranosiduronic acid Featured |
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| DC66599 | β-D-Glucopyranosiduronic acid, tetradecyl Featured |
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| DC66600 | BLU-222 Featured | BLU-222 is an investigational, oral, potent, and selective CDK2 inhibitor. BLU-222 has shown robust anti-tumor activity in preclinical models of CCNE-aberrant ovarian, breast and gastric cancer. |
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| DC66601 | Zoniporide Featured |
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| DC66602 | Gepotidacin mesylate Featured | Gepotidacin, also known as GSK-2140944, is a potent Type II DNA topoisomerase inhibitor. Gepotidacin is a novel antibacterial drug candidate. Gepotidacin Demonstrates Absence of Fluoroquinolone-Like Arthropathy in Juvenile Rats. Gepotidacin is efficacious in a nonhuman primate model of pneumonic plague. When tested against Gram-negative (n = 333) and Gram-positive (n = 225) anaerobes by agar dilution, gepotidacin inhibited 90% of isolates at concentrations of 4 and 2 μg/mL, respectively. |
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| DC66603 | IWY357 Featured |
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| DC66604 | EOS-984 Featured |
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| DC66605 | NDI-101150 Featured |
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| DC66606 | TYRA-300 Featured | TYRA-300 is the first oral selective FGFR3 inhibitor with IC50 of 11 nM in Ba/F3 cells, and shows selectivity over FGFR1, FGFR2 and FGFR4 in Ba/F3 cells was 25-, 14-, and 36-fold, respectively. TYRA-300 demonstrates equivalent potency for FGFR3 WT and V555M/L gatekeeper mutations in enzymatic assays and in engineered RT112/84 and UM-UC-14 bladder cancer cell lines containing the V555M mutation. |
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| DC66607 | BAY2925976 Featured |
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| DC66608 | BMS-986397 Featured |
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| DC66609 | PLX-4545 Featured |
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| DC66610 | Castadifan Featured |
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| DC66611 | PF-07328948 Featured |
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| DC66612 | VVD-130037 Featured | VVD-130037 is an oral covalent activator of KEAP/NRF2 degrader. |
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| DC66613 | BMS-986308 Featured | BMS-986308 is a selective and orally active renal outer medullary potassium (ROMK) channel inhibitor. BMS-986308 is selective for ROMK over hERG. BMS-986308 can be used for heart failure research. |
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| DC60636 | Acid-degradable Cationic Lipid (ADC) Featured | Acid-degradable Cationic Lipid (ADC) composed of cationic lipid is synthesized with the azido-acetal linker and used to generate RD-LNPs, which significantly improves the performance of LNP-mRNA complexes in vitro and in vivo. |
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| DC60637 | BI-9508 Featured | BI-9508 is a potent and selective, brain-penetrant GPR88 agonist with EC50 of 47 nM. |
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| DC66614 | Vc-seco-duba Featured | Vc-seco-DUBA (SYD985) is a agent-linker conjugate for ADC with potent antitumor activity by using DUBA (DNA alkylating agent), linked via the ADC linker Vc-seco. |
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| DC66615 | Glucocorticoid receptor agonist-1 phosphate Gly-Glu-Br Featured | Glucocorticoid receptor agonist-1 phosphate Gly-Glu-Br is an ADC linker that can be used to synthesize ABBV-154, ABBV-927, ABBV-368 or their analogs. |
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| DC66616 | Sulfo-PDBA-DM4 Featured | Sulfo-PDBA-DM4 is a agent-linker conjugate composed of a potent a tubulin inhibitor DM4 and a linker Sulfo-PDBA to make antibody agent conjugate (ADC). Sulfo-PDBA is a gluthatione cleavable linker. |
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| DC66617 | Mal-amido-PEG6-NHS ester Featured | Mal-amido-PEG6-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
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| DC66618 | 4-(pyridin-2-yldisulfanyl)-2-sulfobutanoic acid DIEA Salt Featured |
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| DC66619 | Val-Ala-PAB Featured | Val-Ala-PAB is a cleavable ADC linker that can be used for ADCs synthesis. |
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| DC66620 | Fomc-Gly-Gly-Phe-Gly-OH Featured | Fomc-Gly-Gly-Phe-Gly-OH (compound D5) can be used as an intermediate in the synthesis of ADC dual-drug-linker. Fomc-Gly-Gly-Phe-Gly-OH synthetic intermediate GGFGE further forms an important ADC dual-drug link assembly unit. |
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| DC66621 | Fmoc-GGFL-OH Featured |
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| A050 | Licaminlimab Biosimilar(Anti-TNFSF2 / TNFa Reference Antibody ) Featured | Licaminlimab (OCS-02) is a single-chain anti-TNF alpha antibody fragment. TNF alpha is an inflammatory cytokine produced by macrophages and monocytes during inflammation. |
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| A051 | Gremubamab Biosimilar (Anti-PcrV Reference Antibody ) Featured | Gremubamab (MEDI3902) is a humanized IgG1 kappa anti-PcrV/Psl monoclonal antibody. Gremubamab binds to the PA PcrV protein and Psl exopolysaccharide. Gremubamab has the potential for the research of pseudomonas aeruginosa infections. |
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