A253 |
Centocor patent anti-IL-25 Biosimilar(Anti-IL-25 Reference Antibody)
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A254 |
Dacliximab Biosimilar(Anti-IL-2Ra / CD25 Reference Antibody)
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Daclizumab (Zenapax) is a humanized, monoclonal antibody that blocks CD25 (α-subunit of the high-affinity interleukin-2 receptor (IL-2R-HA)). Daclizumab (Zenapax) reversibly binds to CD25and prevents the interaction of IL-2 with the IL-2R-HA. Daclizumab (Zenapax) can be used for multiple sclerosis research. |
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A255 |
Camidanlumab Biosimilar(Anti-IL-2Ra / CD25 Reference Antibody)
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Camidanlumab (HuMax-TAC) is a CD25 monoclonal antibody. Camidanlumab targets the cell-surface antigen CD25, which is over-expressed on a variety of hematological tumors and shows limited expression on normal tissues. Camidanlumab can be used for synthesis of antibody agent conjugates (ADCs) to research several diseases including lymphoma and leukemia. |
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A256 |
Singapore ASTR patent anti-IL-2R beta / IL-2R gamma Biosimilar(Anti-IL-2Rb / CD122 Reference Antibody)
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A257 |
Nemolizumab Biosimilar(Anti-IL-31Ra Reference Antibody)
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Nemolizumab (CIM331) is a humanized antihuman interleukin-31 receptor A monoclonal antibody that inhibits the binding of interleukin-31 (IL-31) to its receptor and subsequent signal transduction. Nemolizumab can used be in research of atopic dermatitis (AD). |
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A258 |
Itepekimab Biosimilar(Anti-IL-33 Reference Antibody)
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Itepekimab (REGN-3500) is an IgG4 monoclonal antibody against IL-33. Itepekimab reduced airway inflammation and related tissue damage in preliminary clinical studies. Itepekimab has potential effects in asthma, chronic obstructive pulmonary disease (COPD), and atopic dermatitis (AD). |
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A259 |
Tozorakimab Biosimilar(Anti-IL-33 Reference Antibody)
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Tozorakimab (MEDI-3506) is a human immunoglobulin G1 monoclonal antibody targeting interleukin-33. Tozorakimab reduces inflammation and epithelial dysfunction. Tozorakimab can be used to research chronic obstructive pulmonary disease. |
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A260 |
Torudokimab Biosimilar(Anti-IL-33 Reference Antibody)
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A261 |
Etokimab Biosimilar(Anti-IL-33 Reference Antibody)
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Etokimab (Antibody ANB 020) is a humanized monoclonal antibody that targets IL-33. Etokimab can be used for the research of atopic dermatitis. |
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A262 |
Talacotuzumab Biosimilar(Anti-IL-3Ra / CD123 Reference Antibody)
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Talacotuzumab (JNJ 56022473; CSL 362) is an IgG1-type fully humanized, CD123-neutralizing monoclonal antibody containing a modified Fc structure. Talacotuzumab has KDs of 0.43 nM, 188 nM, 46 nM, 16.8 nM for CD123, CD32b/c, CD16-158F, CD16-158V, respectively. Talacotuzumab inhibits IL-3 binding to CD123, antagonizing IL-3 signaling in target cells. Talacotuzumab has mutated the Fc region to increase affinity for CD16 (FcγRIIIa), thereby enhancing antibody-dependent cell-mediated cytotoxicity (ADCC). Talacotuzumab is highly effective in vivo reducing leukemic cell growth in acute myeloid leukemia (AML) xenograft mouse models. |
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A263 |
SNG-CD123A Biosimilar(Anti-IL-3Ra / CD123 Reference Antibody)
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A264 |
MEDI2045 Biosimilar(Anti-IL-4Ra / CD124 Reference Antibody)
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A265 |
Depemokimab Biosimilar(Anti-IL-5 Reference Antibody)
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Depemokimab (GSK-3511294) is a long-acting anti-IL-15 monoclonal antibody. Depemokimab can be used for research of asthma. |
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A266 |
Abgenix anti-IL-5 Biosimilar(Anti-IL-5 Reference Antibody)
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DC66871 |
1-Propanone, 1-(3-chlorophenyl)-3-(methylthio)-
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DC66872 |
4-Hepten-3-one, 1,7-bis(4-hydroxy-3-methoxyphenyl)-
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DC66873 |
4-Hepten-3-one, 1,7-bis(4-hydroxy-3-methoxyphenyl)-, (4Z)-
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DC66874 |
WAY-311207-A
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DC66875 |
CDK1-IN-2
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CDK1-IN-2 is a CDK1 inhibitor (IC50: 5.8 μM). |
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DC66876 |
Rpn11-IN-1
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DC66877 |
New Red
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New Red is a color additive that can be used to dye flour as well as meat products. |
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DC66878 |
9-(dimethylamino)-3-(4-ethylphenyl)pyrido[1,2]thieno[3,4-d]pyrimidin-4-one
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DC66879 |
ST-14328
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DC66880 |
8-Quinolinecarboxamide, 1,2-dihydro-2,2,4-trimethyl-N-[(1S,2E)-3-(methylsulfonyl)-1-(phenylmethyl)-2-propen-1-yl]-
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DC66881 |
WNK1-IN-1
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WNK1-IN-1 is a selective inhibitor of WNK1 with an IC50 value of 1.6 μM. WNK1-IN-1 inhibits OSR1 phosphorylation with an IC50 value of 4.3 μM. WNK1-IN-1 can be used for the research of blood pressure regulation and cancer. |
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DC66882 |
sRANKL inhibitor S3-15
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sRANKL inhibitor S3-15 is a highly potent, orally active inhibitor of soluble RANKL, selectively interrupt soluble RANKL-RANK interaction and without interfering with the membrane RANKL-RANK interaction, shows potent osteoclast inhibition effect with IC50 of 0.19 uM in vitro. |
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DC66883 |
Halosulfuron
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DC66884 |
Clenpenterol Hydrochloride
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DC66885 |
Vitamin K5 hydrochloride
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Vitamin K5 (hydrochloride) is a naphthoquinones compound, shows trichomonacidal activity in vitro. Vitamin K5(hydrochloride) can be used for the research of anti-infection. |
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DC66886 |
7α-Hydroxycholesterol
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7α-Hydroxycholesterol is a cholesterol oxide and is formed by both enzymatic and non-enzymatic oxidation. 7α-Hydroxycholesterol can be used as a biomarker for lipid peroxidation. |
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