| A303 |
ADCT-901 Biosimilar（Anti-KAAG1 Reference Antibody）
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| A304 |
ADCT-901-MMAE Biosimilar(Anti-KAAG1 Reference Antibody)
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| A305 |
Macrogenics patent anti-KID3 Biosimilar(Anti-KID3 Reference Antibody)
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| A306 |
Lirilumab Biosimilar(Anti-KIR Reference Antibody)
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Lirilumab (IPH2102) is an anti-KIR monoclonal antibody, and shows antitumor activity. Lirilumab can be used in Leukemia, squamous cell carcinoma of the head and neck (SCCHN) research. |
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| A307 |
Innate patent anti-KIR2DL Biosimilar(Anti-KIR2DL1 / CD158a Reference Antibody)
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| A308 |
Lacutamab Biosimilar(Anti-KIR3DL2 / CD158k Reference Antibody)
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Lacutamab (IPH4102) is a humanizedized monoclonal antibody (mAb) directed against the immune receptor molecule KIR3DL2, produced by recombinant technology in CHO cells. Lacutamab can be used in research of cutaneous T-cell lymphoma. |
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| A309 |
JNJ-69086420 Biosimilar(Anti-KLK2 / Kallikrein 2 Reference Antibody)
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| A310 |
Genentech patent anti-KLK5 Biosimilar(Anti-KLK5 / Kallikrein 5 Reference Antibody )
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| A311 |
NGM313 Biosimilar(Anti-Klotho Beta Reference Antibody)
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| A312 |
RG7992 Biosimilar(Anti-Klotho Beta Reference Antibody)
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| A313 |
Fianlimab Biosimilar(Anti-LAG3 / CD223 Reference Antibody)
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Fianlimab (REGN3767) is a human monoclonal antibody that targets the immune checkpoint receptor LAG-3 on T cells and has anti-tumour activity. |
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| A314 |
Favezelimab Biosimilar(Anti-LAG3 / CD223 Reference Antibody)
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Favezelimab (MK-4280) is a humanized anti-LAG-3 monoclonal antibody that blocks the interaction between LAG-3 and its ligand MHC class II. Favezelimab has the potential for colorectal cancer (CRC) research combined with the PD-L1 inhibitor Pembrolizumab (HY-P9902). |
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| A315 |
Ieramilimab Biosimilar(Anti-LAG3 / CD223 Reference Antibody)
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Ieramilimab (LAG525; IMP701) is a humanized IgG4 monoclonal antibody that binds to LAG-3, resulting in inhibition of LAG-3 interaction with MHC-II molecules. |
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| A316 |
Encelimab Biosimilar(Anti-LAG3 / CD223 Reference Antibody)
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Encelimab is an anti-LAG3 antibody. Encelimab blocks the interaction between LAG-3 and MHC II, and enhances T-cell activation. Encelimab alone or in combination with an anti-PD-1 antibody reduces tumor size in a lymphoma mice model (A20 cell xenograft). |
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| A317 |
Relatlimab Biosimilar(Anti-LAG3 / CD223 Reference Antibody)
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Relatlimab (BMS-986016) is a human monoclonal antibody anti-LAG-3 antibody generated by immunization of transgenic mice bearing human immunoglobulin miniloci with recombinant LAG-3 protein. Relatlimab blocks LAG-3/MHC II interaction with an IC50 value of 0.67 nM and LAG-3/FGL1 interaction with an IC50 value of 0.019 nM. Relatlimab can be used in research of cancer. |
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| A318 |
Miptenalimab Biosimilar(Anti-LAG3 / CD223 Reference Antibody)
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Miptenalimab (BI-754111) is an anti-human LAG-3 antibody (KD: 88.6 nM for h LAG-3). Miptenalimab blocks the interaction of LAG-3 with its ligand MHC-II. |
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| A319 |
SAR428926 Biosimilar(Anti-LAMP1 / CD107a Reference Antibody)
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| A320 |
Brigham and Womens anti-LAP Biosimilar(Anti-LAP Reference Antibody)
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| A321 |
Mibavademab Biosimilar(Anti-LEPR / CD295 Reference Antibody)
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| A322 |
MB-311 Biosimilar(Anti-Lewis Y Reference Antibody)
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| A323 |
MSC-1 Biosimilar(Anti-LIF Reference Antibody)
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| DC66946 |
Patulin
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Patulin (Terinin) is a mycotoxin produced by fungi including the Aspergillus, Penicillium, and Byssochlamys species, causes chromosome breakage, mutation, teratogenic and cytotoxic. Patulin induces autophagy-dependent apoptosis through lysosomal-mitochondrial axis, and causes DNA damage. |
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| A324 |
Polzastobart Biosimilar（Anti-LILRB2 / ILT4 / CD85d Reference Antibody）
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Polzastobart (JTX-8064) is a humanized IgG4 monoclonal antagonist antibody that selectively binds LILRB2 and prevents it from binding its ligands, classical and non-classical MHC I molecules. Polzastobart enhances pro-inflammatory cytokine production in macrophages by blocking the ability of LILRB2 to bind HLA-A/B and/or HLA-G, a marker of immunotolerance on cancer cells. Polzastobart is a macrophage immune checkpoint inhibitor. |
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| A325 |
Merck patent anti-ILT3 complex Biosimilar（Anti-LILRB4 / ILT3 / CD85k Reference Antibody）
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| A326 |
U.Texas patent anti-LILRB4 Biosimilar（Anti-LILRB4 / ILT3 / CD85k Reference Antibody）
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| A327 |
Opicinumab Biosimilar（Anti-LINGO1 Reference Antibody）
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Opicinumab (BIIB033) is a monoclonal antibody against LINGO-1 and has potential application in acute optic neuritis and relapse multiple sclerosis. |
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| A328 |
Ladiratuzumab Biosimilar（Anti-LIV-1 / SLC39A6 Reference Antibody）
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Ladiratuzumab (hLIV22) is an anti-LIV-1/ZIP6 humanized monoclonal antibody. Ladiratuzumab, conjugated with the microtubule disrupting agent, MMAE (HY-15162) to compose SGN-LIV1A, an antibody-drug conjugate (ADC). Ladiratuzumab can be used for research of breast cancer. |
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| DC66951 |
Aflatoxin M2
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Aflatoxin M2 is a major metabolite of Aflatoxin B1. Aflatoxin M2 is a mycotoxin produced by the fungi Aspergillus flavus and Aspergillus parasiticus. The level of toxicity associated with Aflatoxin is Aflatoxin B1>Aflatoxin M1>Aflatoxin G1>Aflatoxin B2>Aflatoxin M2>Aflatoxin G2. |
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| A329 |
Simtuzumab Biosimilar（Anti-LOXL2 Reference Antibody）
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Simtuzumab (AB 0024; GS 6624) is a monoclonal antibody directed against Lysyl oxidase like-2 (LOXL2). Simtuzumab can be used for the research of primary sclerosing cholangitis (PSC). |
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| A330 |
RG7841 Biosimilar（Anti-Ly6E Reference Antibody）
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