| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC9169 | Chloroquine diphosphate | Chloroquine diphosphate is an antimalarial drug and autophagy/lysosome inhibitor; inhibits Toll-like receptor (TLR) signalling in plasmacytoid dendritic cells (pDCs). |
|
| DCAPI1270 | Chlorothiazide | Chlorothiazide |
|
| DC9111 | Chlorpheniramine Maleate | Chlorpheniramine maleate is an histamine H1 receptor antagonist with IC50 of 12 nM. |
|
| DC9082 | Chlorpromazine HCl Featured | Chlorpromazine Hydrochloride is a dopamine and potassium channel inhibitor used as the prototypical phenothiazine antipsychotic drug. |
|
| DC9062 | Chlorprothixene | Chlorprothixene has strong binding affinities to dopamine and histamine receptors, such as D1, D2, D3, D5, H1, 5-HT2, 5-HT6 and 5-HT7, with Ki of 18 nM, 2.96 nM, 4.56 nM, 9 nM, 3.75 nM, 9.4 nM, 3 nM and 5.6 nM, respectively. |
|
| DCAPI1339 | Chlorthalidone (Chlortalidone) | Chlortalidone is a diuretic drug used to treat hypertension. |
|
| DC9194 | Chlorzoxazone | Chlorzoxazone is a centrally acting muscle relaxant used to treat muscle spasm and the resulting pain or discomfort. It acts on the spinal cord by depressing reflexes.Chlorzoxazone is currently being used as a marker substrate in vitro/vivo studies to qua |
|
| DC20623 | CHMFL-ABL-053 | CHMFL-ABL-053 is a potent, selective and orally available Bcr-Abl/Src/p38 kinase inhibitor with IC50 of 70/62/90 nM. |
|
| DC10467 | CHMFL-BMX-078 Featured | CHMFL-BMX-078 is a highly potent and selective type II irreversible BMX kinase inhibitor with an IC50 of 11 nM. |
|
| DC20339 | CHMFL-KIT-031 | CHMFL-KIT-031 is a highly selective KIT kinase primary V559D mutant inhibitor with IC50/Kd of 28/266 nM, 10-20 fold selectivity over KIT wt. |
|
| DC20069 | CHMFL-PI3KD-317 | CHMFL-PI3KD-317 is a highly potent, selective and orally active PI3Kδ inhibitor, with an IC50 of 6 nM, and exhibits over 10-1500 fold selectivity over other class I, II and III PIKK family isoforms, such as PI3Kα (IC50, 62.6 nM), PI3Kβ (IC50, 284 nM), PI3 |
|
| DC12199 | Cholestenone | Cholestenone is the intermediate oxidation product of cholesterol. |
|
| DC20181 | Choline Fenofibrate;ABT-335 | Choline fenofibrate is a newly developed choline salt of fenofibric acid, a synthetic phenoxy-isobutyric acid derivate with antihyperlipidemic activity that acts as an PPARα agonist. |
|
| DC8116 | Tosedostat (CHR2797) Featured | CHR-2797 is an aminopeptidase inhibitor, with IC50 values of 100 nM for LAP3 (LAP), 150 nM for PSAP (PuSA) and 220 nM for CD13 (Aminopeptidase N). |
|
| DC22173 | CHR-3996 | CHR-3996 (Nanatinostat, VRx-3996, CHR3996, Tractinostat) is a potent, class I-selective, orally active HDAC inhibitor with IC50 of 3-7 nM for HDAC1/2/3. |
|
| DC9460 | CHR-6494 Featured | CHR-6494 is a potent and selective Haspin (Haploid Germ Cell-Specific Nuclear Protein Kinase) inhibitor that blocks H3T3ph phosphorylation. |
|
| DC8139 | GMX1778(CHS-828) Featured | CHS-828 is a pyridyl cyanoguanidine anti-tumor agent that has been identified as a competitive inhibitor of Nampt as well as an inhibitor of NF-κB pathway activity. |
|
| DC12329 | ChX710 | ChX710 could prime the type I interferon response to cytosolic DNA, which induces the ISRE promoter sequence, specific cellular Interferon-Stimulated Genes (ISGs), and the phosphorylation of Interferon Regulatory Factor (IRF) 3. |
|
| DC10341 | CHZ868 | CHZ868 is a type II JAK2 inhibitor with an IC50 of 0.17 μM in EPOR JAK2 WT Ba/F3 cell. |
|
| DC2088 | CI-1040 (PD184352) Featured | CI-1040 (PD 184352) is an ATP non-competitive MEK1/2 inhibitor with IC50 of 17 nM. |
|
| DC20893 | CI-1044 | CI-1044 is a potent, selective and orally bioavailable PDE4 inhibitor with IC50 of 0.27 uM, displays high selectivity for PDE4 versus PDE1/3/5, and no PDE4 subtype (4A-D) selectivities. |
|
| DC21462 | CI-966 | CI-966 (PD 126141) is a potent, selective inhibitor of the GABA transporter GAT-1 with IC50 of 0.26 and 1.2 uM for human and rat GAT-1, respectively. |
|
| DC20894 | CI-966 hydrochloride | CI-966 is a potent, selective inhibitor of the GABA transporter GAT-1 with IC50 of 0.26 and 1.2 uM for human and rat GAT-1, respectively. |
|
| DC21463 | CI-976 Featured | CI-976 (PD 128042) is a potent, selective, orally bioavailable inhibitor of ACAT-1 (Acetyl-CoA acetyltransferase 1) with IC50 of 73 nM. |
|
| DC2060 | CI994 (Tacedinaline) Featured | CI994 (Tacedinaline) is an anti-cancer drug which inhibits HDAC1 with IC50 of 0.57 μM. |
|
| DC12412 | cIAP1 E3 ligase inhibitor D19 | cIAP1 E3 ligase inhibitor D19 (cIAP1 inhibitor D19) is a small-molecule inhibitor of E3 ligase activity of cIAP1, inhibits cIAP1 auto-ubiquitination with IC50 of 14.1 uM, shows no effect on autoubiquitination of BRCA1/BARD1. |
|
| DC12413 | cIAP1 E3 ligase inhibitor D19-14 | cIAP1 E3 ligase inhibitor D19-14 (cIAP1 inhibitor D19-14) is an improved analog of D19, demonstrates significantly increased ability to inhibit cIAP1 autoubiquitination and reduce protein levels of c-MYC in vitro. |
|
| DC9176 | Ciclesonide | Ciclesonide(RPR251526) is a glucocorticoid used to treat obstructive airway diseases. |
|
| DCAPI1143 | Ciclopirox (Penlac) | Ciclopirox (Penlac) |
|
| DC12285 | CID 1375606 Featured | CID 1375606 is a surrogate agonist of orphan G protein-coupled receptor GPR27. |
|
