DC10873 |
CID16020046
Featured
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CID 16020046 is a potent and selective GPR55(LPI receptor) antagonist; inhibitsGPR55 constitutive activity with IC50 of 0.15 uM. |
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DC22056 |
CID 9998128 |
CID 9998128 is a potential multi-target drug for the Alzheimer's disease (AD), inhibits the Aβ42 amyloid fibrillization and is capable to clear Aβ42 fibrils. |
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DC12243 |
CID-1067700 |
CID-1067700 is a pan GTPase inhibitor, and competitively inhibits Ras-related in brain 7 (Rab7) with a Ki of 13 nM. |
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DC7253 |
CID-2011756
Featured
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CID-2011756 is a cell-active ATP competitive and specific PKD1 inhibitor that inhibits phorbol ester-induced endogenous PKD1 activation in LNCaP prostate cancer cells. |
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DC8849 |
CID-2858522
Featured
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CID-2858522 is a selectively inhibits protein kinase C (PKC)-induced activation of the NF-κB pathway (IC50 < 0.1 μM for PMA-stimulated IL-8 production). |
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DC20895 |
CID3528206 |
CID3528206 is a potent, small molecule yeast TORC1 inhibitor that inhibits TORC1 activity both in vitro and in vivo with IC50 of 150 nM and 3.9 uM, respectively. |
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DC9955 |
BCL6 inhibitor(CID5721353)
Featured
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CID5721353 is a B-Cell Lymphoma 6 Inhibitor (BCL6 inhibitor). |
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DC7385 |
CID-755673
Featured
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CID755673 is a potent and selective cell-active small molecule inhibitor for PKD with an IC50 of 182 nM; exhibits selective PKD1 inhibition when compared with AKT, PLK1, CAK, CAMKIIα, and PKC isoforms. |
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DC7976 |
CID 797718
Featured
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CID-797718 is a compound with unknown details. |
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DC23753 |
CID888706 |
CID888706 is a small molecule, pan activator of Rho-family GTPases.. |
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DC20904 |
CIDD 0067106 |
CIDD 0067106 is a novel natural product-based diaryloxazole that potent and selective antiproliferative activities against androgen receptor-positive breast cancer cells (MDA-MB-453 cell GI50=0.8 uM). |
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DCAPI1021 |
Cidofovir(Vistide)
Featured
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Cidofovir(Vistide) |
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DC10839 |
CIL56(CA3)
Featured
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CIL56 is a small molecule that induces cellular ferroptosis through production of iron-dependent reactive oxygen species (ROS). |
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DC11374 |
Cilastatin |
Cilastatin is an inhibitor of dipeptidase (dehydropeptidase I), a renal dipeptidase. |
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DCAPI1569 |
Cilostazol |
Cilastazol is a 2-oxo-quinoline with vasodilator, antimitogenic, antithrombotic, and cardiotonic properties. This compound has been shown to cause inhibition of adenosine uptake, eventually resulting in changes to cAMP levels. Studies have shown Cilostazo |
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DC9325 |
Cilazapril (monohydrate)
Featured
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Cilazapril Monohydrate is a angiotensin-converting enzyme (ACE) inhibitor used for the treatment of hypertension and congestive heart failure.
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DC7561 |
Cilengitide (TFA salt)
Featured
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Cilengitide is a potent integrin inhibitor for αvβ3 receptor and αvβ5 receptor with IC50 of 4.1 nM and 79 nM, respectively; ~10-fold selectivity against gpIIbIIIa. Phase 2. |
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DC9875 |
Ciliobrevin A(HPI4)
Featured
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Ciliobrevin A(HPI-4) is a Hedgehog pathway inhibitor and ciliogenesis inhibitor. |
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DC20341 |
Ciliobrevin D
Featured
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Ciliobrevin D is a cell-permeable, reversible, specific inhibitor of cytoplasmic dynein, blocks dynein-dependent microtubule gliding and ATPase activity while sparing kinesin dependent cellular trafficking. |
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DC9160 |
Cilnidipine
Featured
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Cilnidipine(FRC8653) is a dual L- and N-type calcium channel blocker and displays antihypertensive, sympatholytic and neuroprotective activity. |
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DC10868 |
Cilofexor
Featured
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Cilofexor (GS-9674, GS9674) is novel specific, non-steroidal farnesoid X receptor (FXR) agonist that reduces liver fibrosis and ameliorates portal hypertension in rat NASH models. |
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DC9582 |
Cilomilast |
Cilomilast(SB 207499; Ariflo) is a potent PDE4 inhibitor with IC50 of about 110 nM, has anti-inflammatory activity and low central nervous system activity. |
|
DC22028 |
Ciluprevir |
Ciluprevir (BILN2061) is a potent HCV NS3/4A protease inhibitor with Ki of 0.66 and 0.30 nM for NS3-NS4A protease of HCV 1b and HCV 1a, respectively. |
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DC9002 |
Cimetidine |
Cimetidine is a histamine-2 (H2) receptor antagonist. |
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DC12134 |
Cimiside B |
Cimiside B, a glycoside alkaloid, isolated from the rhizome of Cimicifuga dahurica. |
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DC8801 |
Cinacalcet (AMG-073)
Featured
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Cinacalcet(AMG-073) is an orally active, second-generation calcimimetic compound; AMG 073 represents a new class of compounds for the treatment of hyperparathyroidism. |
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DC12369 |
Cinaciguat (hydrochloride)
Featured
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Cinaciguat is an activator of sGC that binds to a regulatory site, resulting in activation in an NO-independent manner (Kd = 3.2 nM). |
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DC20093 |
Cinchonine ((8R,9S)-Cinchonine; LA40221)
Featured
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Cinchonine is a natural compound present in Cinchona bark. Cinchonine activates endoplasmic reticulum stress-induced apoptosis in human liver cancer cells. |
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DC9174 |
Cinepazide maleate |
Cinepazide Maleate is a vasodilator. |
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DC9896 |
Cinnarizine
Featured
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Cinnarizine is a medication derivative of piperazine, and characterized as an antihistamine and a calcium channel blocker. |
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