| DC21345 |
Contezolid |
Contezolid (MRX I) is an orally active oxazolidinone agent with antibacterial activity Gram-positive pathogens, including MRSA, penicillin-PRSP, PISP, and vancomycin-resistant enterococci (VRE) with MIC of 0.25-4 ug/mL. |
|
| DC11048 |
Contilisant |
Contilisant is a neuroprotective, non-toxic, antioxidant, permeable ligand, showing in vitro pharmacological properties on the selected biological targets (hAChE IC50=0.53 uM. |
|
| DC10776 |
Cordycepin
Featured
|
Cordycepin is an adenosine analogue, which is readily phosphorylated to its mono-, di-, and triphosphate intracellularly. It has a very potent anti-cancer, anti-oxidant and anti-inflammatory activities. |
|
| DC12098 |
Corin
Featured
|
Corin is a dual inhibitor of histone lysine specific demethylase (LSD1) and histone deacetylase (HDAC), with a Ki(inact) of 110 nM for LSD1 and an IC50 of 147 nM for HDAC1. |
|
| DC11104 |
Tildacerfont
Featured
|
corticotropin releasing factor (CRF) antagonist. |
|
| DC22488 |
Corticotropin-releasing factor (human)
Featured
|
Corticotropin-releasing hormone (CRH) is a peptide hormone involved in the stress response.. |
|
| DC22479 |
Cortisone acetate |
Cortisone acetate (Cortisone 21-acetate) is a synthetic glucocorticoid corticosteroid and corticosteroid ester. |
|
| DC23908 |
Cortisone
Featured
|
Cortisone is a pregnane (21-carbon) steroid hormone, one of the main hormones released by the adrenal gland in response to stress. |
|
| DC8694 |
Cortodoxone |
Cortodoxone is a glucocorticoid steroid hormone that can be oxygenated to cortisol (Hydrocortisone). |
|
| DC10686 |
Cosan-528
Featured
|
Cosan-528 is a bioactive chemical. |
|
| DC9554 |
Cot inhibitor-1 |
Cot inhibitor-1 is a COT/Tpl2 inhibitor. |
|
| DC9555 |
Cot inhibitor-2 |
Cot inhibitor-2 is a COT/Tpl2 inhibitor. |
|
| DC10657 |
COTI-2
Featured
|
COTI-2 is a small molecule candidate anti-cancer drug which can convert mutant p53 to wild-type conformation. |
|
| DC20933 |
Cotylimide-VI |
Cotylimide-VI (CTL-VI) is a small molecule that perturbs plant hormone strigolactone accumulation and inhibits hypocotyl growth.. |
|
| DC10363 |
Coumestrol
Featured
|
Coumestrol, a phytoestrogen present in soybean products, exhibits activities against cancers, neurological disorders, and autoimmune diseases. It suppresses proliferation of ES2 cells with an IC50 of 50 μM. |
|
| DC21413 |
Cowanin |
Cowanin is a novel natural product from Garcinia speciosa that inhibits the Notch signaling pathway with IC50 of 2.4 uM. |
|
| DC10528 |
CP 376395
Featured
|
CP 376395 is a potent and selective CRF1 receptor antagonist (Ki values are 12 and >10000 nM for CRF1 and CRF2 receptors respectively). |
|
| DC8543 |
CP465022 HCl |
CP 465022 hydrochloride is a selective GluR (AMPA) antagonist which is non-competitive. |
|
| DC7389 |
CP-673451
Featured
|
CP 673451 is a selective inhibitor of PDGFRα/β with IC50 of 10 nM/1 nM, exhibits >450-fold selectivity over other angiogenic receptors, has antiangiogenic and antitumor activity. |
|
| DC12046 |
CP 105696
Featured
|
CP-105696 is a potent and selective Leukotriene B4 Receptor antagonist, with an IC50 of 8.42 nM. |
|
| DC9726 |
CP21 (CP21R7)
Featured
|
CP21R7 is a potent and selective GSK-3β inhibitor. |
|
| DC23320 |
CP 31398 dihydrochloride
Featured
|
CP-31398 is a small molecule p53 reactivator that protects p53 from thermal denaturation, not only reactivates mutant p53 but also induces stabilization of wild type p53. |
|
| DC23610 |
CP-339818 hydrochloride
Featured
|
CP-339818 is a potent, selective, non-peptide KV1.3 channel antagonist with IC50 of 200 nM. |
|
| DC4112 |
CP466722
Featured
|
CP-466722 is an potent and reversible ATM inhibitor. |
|
| DC23415 |
CP-481715 |
CP-481715 is a potent and selective CCR1 antagonist with Ki of 9.2 nM and IC50 of 74 nM, lacks intrinsic agonist activity and . |
|
| DC9303 |
Taprenepag(CP-544326)
Featured
|
CP-544326 is a selective prostaglandin EP(2) agonist on intraocular pressure in preclinical models of glaucoma. |
|
| DC4132 |
CP-547632
Featured
|
CP-547632 is as a potent inhibitor of the VEGFR-2 and basic fibroblast growth factor (FGF) kinases (IC50 11 and 9 nM, respectively). |
|
| DC9265 |
CP-640186 hydrochloride
Featured
|
CP-640186 Hcl is an isozyme-nonselective acetyl-CoA carboxylase (ACC) inhibitor with IC50s of 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively; with improved metabolic stability vs CP-610431. |
|
| DC7975 |
CP 640186
Featured
|
CP-640186 is an isozyme-nonselective acetyl-CoA carboxylase inhibitor with IC50s of 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively. |
|
| DC11410 |
CP-671305
Featured
|
CP-671305 is a potent and selective inhibitor of phosphodiesterase 4. |
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