| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC11771 | AZ-27 | A potent non-nucleoside RSV L-protein polymerase inhibitor with EC50 of 0.01 uM and 1.3 uM for RSV A2 and RSV B-WST, respectively. |
|
| DC11773 | BI Compound D | A potent non-nucleoside RSV L-protein polymerase inhibitor with IC50 of 89 nM. |
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| DC22714 | GR-159897 | A potent non-peptide antagonist of tachykinin NK2 receptor with pKi of 9.5 in CHO cells. |
|
| DC24033 | CDDO-EA Featured | A potent Nrf2 activator that upregulates Nrf2 expression and resulted in translocation of Nrf2 into the nucleus.. |
|
| DC11786 | THPN Featured | A potent nuclear receptor TR3 (Nur77)-specific targeting compound that can induce melanoma autophagy through a mitochondrial signaling pathway. |
|
| DCAPI1443 | Lamivudine | A potent nucleoside analog reverse transcriptase inhibitor (nRTI). An analog of cytidine that can inhibit both types (1 and 2) of HIV reverse transcriptase as well as the reverse transcriptase of hepatitis B. Needs to be phosphorylated to its triphosphate |
|
| DC22591 | BMS-690514 | A potent pan HER/VEGFR inhibitor with IC50 of 5/20/60/50 nM for EGFR/HER2/ERBB4/VEGFR2 respectively. |
|
| DC21112 | AR-42 | A potent pan-HDAC inhibitor with IC50 of 16-30 nM, inhibits cell proliferation of P815, C2, and BR cells with IC50 of 0.65, 0.30, and 0.23 uM, respectively. |
|
| DC22925 | BMS-1001 hydrochloride Featured | A potent PD-1/PD-L1 interaction inhibitor with IC50 of 2.25 nM in a homogenous time-resolved fluorescence binding assay.. |
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| DC22928 | BMS-1001 Featured | A potent PD-1/PD-L1 interaction inhibitor with IC50 of 2.25 nM in a homogenous time-resolved fluorescence binding assay.. |
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| DC22936 | BMS-242 | A potent PD-1/PD-L1 interaction inhibitor with IC50 of 6-100 nM in a homogenous time-resolved fluorescence binding assay.. |
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| DC22935 | BMS-200 | A potent PD-1/PD-L1 interaction inhibitor with IC50 of 80 nM in a homogenous time-resolved fluorescence binding assay.. |
|
| DC22510 | AN-3199 | A potent PDE4 inhibitor with IC50 of 94.5 nM.. |
|
| DC22850 | Genz 669178 | A potent PfDHODH inhibitor that exhibits low nanomolar in vitro potency against DHODH from P falciparum, P vivax, and P berghei. |
|
| DC22976 | PDE12-IN-3 | A potent phosphodiesterase 12 (PDE12) with Ki of 17.5 nM, with no activity for related enzyme CNOT6 (Ki>10 uM). |
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| DC22588 | PK-14105 | A potent photoaffinity ligand for the peripheral-type benzodiazepine binding site with Ki of 4 nM. |
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| DC25092 | Wortmannin Featured | A potent PI3K inhibitor with IC50 3 nM, does not inhibit PI4K activity. |
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| DC23322 | Vacuolin-1 Featured | A potent PIKfyve inhibitor that inhibits autophagy by impairing lysosomal maturation, potently and reversibly inhibits autophagosome-lysosome fusion by activating RAB5A. |
|
| DC25048 | CGP-53716 | A potent protein tyrosine kinase inhibitor that shows selectivity for PDGFR in vitro and in cells. |
|
| DC22624 | Asenapine | A potent psychopharmacologic agent that shows high affinity for 5-HT, dopamine, histamine and adrenoceptors. |
|
| DC11772 | AZD-4316 | A potent respiratory syncytial virus (RSV) fusion inhibitor.. |
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| DC22929 | KIN-1400 | A potent RIG-I-like receptor (RLR) agonist that triggers IRF3-dependent innate immune antiviral genes and IFN-β expression. |
|
| DC11647 | JNJ-2408068 Featured | JNJ 2408068 is a potent RSV (respiratory syncytial virus) inhibitor. JNJ2408068 significantly inhibits replication of RSV A and B subtypes in the lungs of cotton rats without any evidence of toxicity. The minimum protective dose of JNJ 2408068 appears to be approximately 0.39 mg/kg[1]. |
|
| DC22791 | Kinase inhibitor C1 | A potent small molecule inhibitor of MELK kinase activity with IC50 of 42 nM. |
|
| DC11830 | WK-298 | A potent small molecule inhibitor that binds and disrupts the MDM2/MDMX-p53 interaction with IC50 of 0.19 uM and 19.7 uM, respectively.. |
|
| DC21417 | NSC 141562 | A potent small-molecule inhibitor of the MIR155 host gene/miR-155 axis. |
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| DC5132 | Tropisetron HCL | A potent SR-3 antagonist |
|
| DC22530 | WEHI-345 analog | A potent Src inhibitor extracted from patent WO/2012003544A1.. |
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| DC20416 | Imipramine Blue | A potent STAT5 inhibitor with a dual mechanism of action, potently inhibits STAT5 through liberation of endogenous phosphatase activity following NADPH oxidase (NOX) inhibition at 200-300 nM. |
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| DC22933 | TLR7-Agonist-31 | A potent TLR7 agonist with EC50 of 59 nM.. |
|
