| Cas No.: | 140926-75-6 |
| Chemical Name: | NSC 5844; NSC-5844; RE 640; RE-640; RE640 |
| Synonyms: | NSC 5844; NSC-5844; RE 640; RE-640; RE640 |
| SMILES: | C1=CC2=C(C=CN=C2C=C1Cl)NCCNC3=C4C=CC(=CC4=NC=C3)Cl |
| Formula: | C20H16Cl2N4 |
| M.Wt: | 383.27 |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | NSC5844 is a 4-aminoquinoline derivative, with antitumor and antimalarial activity. |
| In Vitro: | NSC5844 (Compound 10) is a 4-aminoquinoline derivative, and has antitumor activity with GI50s of 7.35 ± 0.10 μM and 14.80 ± 0.35 μM against MDA-MB-468 and MCF-7 cells, respectively[1]. NSC5844 (Compound 1) is cytotoxic to P. falciparum, inhibits the growth of chloroquine-sensitive (D-6) and -resistant (W-2) clones of P. falciparum, with IC50s of 17 and 27 nM, respectively[2]. |
MSDS
COA
| LOT NO. | DOWNLOAD |
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| 2018-0101 |
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| 2018-0101 |
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